Inflammatory arthritis by Maisie Roberts https://padlet.com/kcr20auu/ii6sxkw7vyvtscos PBL week 5 LO's en-us 2021-10-29 09:27:46 UTC 2023-03-08 10:22:25 UTC hello@padlet.com https://padlet.net/icons/png/1f9b5.png georgiaemeny1 https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1855304042 2021-10-30 09:19:51 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1855304042 Olivia https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1859927863 https://www.youtube.com/watch?v=ld8PhyAHov8&t=4s - great video to help understand the physiology of RA

I also used the crash course book in rheumatology and orthopaedics ]]> 2021-11-01 21:56:29 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1859927863 Olivia https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1859930558 Here is a an old powerpoint I found from my uni during my pharmacy degree. I also like to use the BNF, highly recommend starting to use it as a source and getting used to it]]> 2021-11-01 21:58:36 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1859930558 Olivia https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1859931448 https://www.clinicalkey.com/student/content/book/3-s2.0-B9780702073601000032
 
https://www.clinicalkey.com/student/content/book/3-s2.0-B978070207028000024X#hl0006126
 
I used both of the books given on sofia under this LO, they pretty much give the same info but equally as good, to the point and easy to understand.
]]> 2021-11-01 21:59:15 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1859931448 Olivia https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1859933867 Only used the lecture as thought this was sufficient – but thought the below picture summarised it well.]]> 2021-11-01 22:01:22 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1859933867 Olivia https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1861516381 https://www.youtube.com/watch?v=viP5Ta0K-ho


https://www.clinicalkey.com/student/content/book/3-s2.0-B978032364186900039X - I liked the layout of this book, gave all the info needed

]]> 2021-11-02 12:53:21 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1861516381 SARA https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1862686808 I thought that the 2 screencasts provided were sufficient as they were quite in depth but also easy to understand.
I have linked the second chronic inflammation screencast as there is a short animation near the end that is a really good summary of what we need to know for this LO

https://alt-5f47a5775541f.blackboard.com/bbcswebdav/courses/MED-0005Y-YEAR-21E/JG%20MURPHY/UEA%20WEBSITE%203/CHRONIC%20INFLAMMATION%202021/Chronic%20Inflammation%20and%20Wound%20Healing%20Part%202%20%28Published%29/index.html?one_hash=69B363A811576EBDBB877333231A3F6F&f_hash=7641CF0E41426D8A6EAE1857FDEF5E3C]]> 2021-11-02 19:44:13 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1862686808 Aydie https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1864895074 https://my.clevelandclinic.org/health/diseases/4924-rheumatoid-arthritis        

This article outlines what rheumatoid arthritis is, what causes it (genetics, environment etc) how you can treat it with different medication and what the symptoms of the disease is.
 
]]> 2021-11-03 14:46:59 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1864895074 Aydie https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1864897850 https://www.mayoclinic.org/diseases-conditions/lyme-disease/diagnosis-treatment/drc-20374655
https://www.mayoclinic.org/diseases-conditions/lyme-disease/symptoms-causes/syc-20374651

This clearly outlines what Lyme disease is, the early and late symptoms of it, how it is treated and how you can diagnose it.
 

]]> 2021-11-03 14:47:50 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1864897850 Aydie https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1864987950 https://www.youtube.com/watch?v=yTIZpzoaIT0

This YouTube video clearly explained the concepts of acute inflammation, I recommend watching this and then Joe Murphy's lecture as it allows you to build the foundation knowledge you need first.]]> 2021-11-03 15:13:16 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1864987950 Aydie https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1864993773 https://www.mayoclinic.org/diseases-conditions/reactive-arthritis/symptoms-causes/syc-20354838
https://www.mayoclinic.org/diseases-conditions/reactive-arthritis/diagnosis-treatment/drc-20354843

These two links provide a great depth of detail into what Reactive arthritis is, the pathogens that cause it, what the symptoms are and how to diagnose and treat the condition.

]]> 2021-11-03 15:15:00 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1864993773 Aydie https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1864999768 https://www.youtube.com/watch?v=fQCU7rQbovk
https://www.youtube.com/watch?v=a23A3nAaO0E&t=1s
 
This short video states what psoriatic arthritis is, the pathophysiology behind it, the symptoms, investigation and management.
The second link provides relevant information on ankylosing arthritis.
]]> 2021-11-03 15:16:49 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1864999768 Aydie https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865009777 https://www.youtube.com/watch?v=RlCoizT0L3M
 
This video states the obvious and main inflammatory markers and how they show signs of infection/disease. I couldn't find any more detail than this.
]]> 2021-11-03 15:19:56 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865009777 Aydie https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865020217 https://www.nhs.uk/conditions/rheumatoid-arthritis/treatment/

The NHS website states the most common types of medication, e.g., methotrexate, leflunomide etc and the use of JAK inhibitors and biologics.]]> 2021-11-03 15:22:33 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865020217 Aydie https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865042725 https://www.youtube.com/watch?v=7abUCT0hnYY&t=3219s

Very long video but it demonstrates the comparison of inflammatory and degenerative arthritis and how to distinguish between them, it's worth a watch.]]> 2021-11-03 15:25:14 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865042725 Maisie Roberts kcr20auu https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865074124 Table that clearly shows common causes of polyarticular joint pain and they're presentation.  https://www.aafp.org/afp/2003/0915/p1151.html

https://www.msdmanuals.com/en-gb/professional/musculoskeletal-and-connective-tissue-disorders/pain-in-and-around-joints/pain-in-multiple-joints
Really useful website to see pathophysiology and treatment for the different diagnoses.
https://www.nhs.uk/conditions/joint-pain/
To understand how the differential diagnoses present.]]> 2021-11-03 15:34:47 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865074124 Aydie https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865148807 https://www.youtube.com/watch?v=2jEBTeAgtFY

I'm not sure if this entirely covers the question but it does explain very well how the T cells and MHC work together to prevent autoimmunity.]]> 2021-11-03 15:58:20 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865148807 Olivia https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865246278 https://www.youtube.com/watch?v=snjGL2x6Eus 

https://www.ncbi.nlm.nih.gov/books/NBK499831/

I think these to sources give enough info to cover all the points, to the point and easy to understand ]]> 2021-11-03 16:31:36 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865246278 sara https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865386446 Managing people with long-term conditions (kingsfund.org.uk)

page 16-24 has an entire section on Arthritis (OA and RA) and it clearly talks about the role of primary care and how they should treat and support patients with long term illnesses]]> 2021-11-03 17:23:24 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865386446 sara https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865407855 slightly off topic but when aspirating the joint in spetic or crystal arthropathies (which can be polyarticular) this clinical feature table is handy. 

]]> 2021-11-03 17:31:06 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865407855 sara https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865429351 this table is a nice summary of what central tolerance is/how it differs in T and B cells - becasue when the tolerance mechanism breaks down autoimmune effects are shown.

]]> 2021-11-03 17:39:13 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865429351 Maisie kcr20auu https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865461778 https://www.everydayhealth.com/rheumatoid-arthritis/treatment/the-facts-on-methotrexate-for-ra-treatment/
The website I used to understand how MTX works.
Content (uea.ac.uk)
I mainly used Tanya Marshalls lecture on drugs for RA 


]]> 2021-11-03 17:51:36 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865461778 Maisie kcr20auu https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865465040 Content (uea.ac.uk)
I used Tanya Marshalls lecture on Lyme disease found on monoarticular joint pain week.]]> 2021-11-03 17:52:52 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865465040 Maisie kcr20auu https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865546908 Investigations - Crash Course Rheumatology and Orthopaedics - ClinicalKey Student
I used the book for information on areas I wasn't sure on like Anti-CCP and RF. ]]> 2021-11-03 18:25:25 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865546908 Maisie kcr20auu https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865593394 2021-11-03 18:44:36 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1865593394 Florence https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868106066 I thought the RA and radiology lectures provided most of the required knowledge, whilst the pathology crashcourse textbook provided good visual and clear explanation of the pathophysiology of the disease.]]> 2021-11-04 17:46:10 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868106066 Florence https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868115164 I only used the pathology lecture for this one as it was complete and detailed.]]> 2021-11-04 17:49:39 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868115164 Florence https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868121924 *https://www.ncbi.nlm.nih.gov/books/NBK27156/*https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291482/
Two links to help understand the role of MHCs in autoimmunity. (quite long,very in-depth)]]> 2021-11-04 17:52:05 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868121924 Florence https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868130006 Aside from the pathology lecture , I found this video (which figured during the lecture) as it has everything we really need to know:https://www.youtube.com/watch?v=1SvEdg94qUA 
(uni of dundee, v good recap acute inflammation)

For a more detailed recap on inflammation: https://www.youtube.com/watch?v=Fbzb75HA9M8 

More on blood clotting : https://www.youtube.com/watch?v=R8JMfbYW2p4 (best) https://www.youtube.com/watch?v=x8TLTTyyPfI
]]> 2021-11-04 17:55:23 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868130006 Florence https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868134812 Aside from the pathology lecture, I think that the Medical Sciences textbook (https://www.clinicalkey.com/student/content/book/3-s2.0-B9780702073373000067#hl0005374) is fabulous.]]> 2021-11-04 17:57:19 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868134812 Georgia- https://www.mountsinai.org/health-library/tests/c-reactive-protein georgiaemeny1 https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868586520 this website gave a lot of info about the inflammatory markers, you can just use the search bar to look for what you need. otherwise, I just used crash course 4th edition]]> 2021-11-04 22:56:09 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868586520 Georgia georgiaemeny1 https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868588305 https://www.england.nhs.uk/improvement-hub/wp-content/uploads/sites/44/2020/06/Productive-community-hospital-Multi-Team-Working.pdf
this is quite long but some a quick skim read of some slides s beneficial- just covers generic importance of MDT]]> 2021-11-04 22:57:57 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868588305 Georgia georgiaemeny1 https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868591206 https://www.youtube.com/watch?v=s1zOLraHxyc
https://www.youtube.com/watch?v=snjGL2x6Eus
https://patient.info/doctor/reactive-arthritis-pro]]> 2021-11-04 23:00:56 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868591206 Georgia georgiaemeny1 https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868594599 https://bestpractice.bmj.com/topics/en-gb/524?q=Psoriatic%20arthritis&c=suggested]]> 2021-11-04 23:04:22 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868594599 Georgia georgiaemeny1 https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868595573 https://www.youtube.com/watch?v=POV9izM30LU]]> 2021-11-04 23:05:25 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868595573 Georgia georgiaemeny1 https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868597386 https://www.youtube.com/watch?v=BR9_Tka_2PQ]]> 2021-11-04 23:07:19 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868597386 Georgia georgiaemeny1 https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868598935 https://www.youtube.com/watch?v=KeeIrY4BGWE]]> 2021-11-04 23:08:20 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868598935 Georgia georgiaemeny1 https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868600433 https://www.nice.org.uk/guidance/ng95/chapter/Recommendations]]> 2021-11-04 23:09:54 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868600433 Georgia georgiaemeny1 https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868601437 https://pathways.nice.org.uk/pathways/rheumatoid-arthritis]]> 2021-11-04 23:10:54 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868601437 Max https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868650572 This website goes into great detail on the MHC II and immune tolerance]]> 2021-11-04 23:53:45 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868650572 Olivia https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868853538 https://www.niaid.nih.gov/research/immune-tolerance

https://clinicalkeymeded.elsevier.com/reader/books/9780702068010/epubcfi/6/84[%3Bvnd.vst.idref%3Did_chp0028]!/4/2/24/2[s0025]/8/2[s0030]/12[p0155]/1:396[the%2C%20de]

]]> 2021-11-05 01:36:28 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1868853538 Nelson https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1869473806 Used crash course and the lecture
https://www.clinicalkey.com/student/content/book/3-s2.0-B9780702073601000123]]> 2021-11-05 08:25:04 UTC https://padlet.com/kcr20auu/ii6sxkw7vyvtscos/wish/1869473806