DNA MUTATIONS by John Miranda

MUTATIONS

johnmiranda — 2021-01-21 19:18:11 UTC

A permanent change in the sequence of a cell's DNA

SINGLE GENE

johnmiranda — 2021-01-21 19:18:25 UTC

Change in a single base pair within a DNA sequence.

CHROMOSOMAL MUTATIONS

johnmiranda — 2021-01-21 19:18:35 UTC

Changes in chromosome structure. It involves many genes.

SILENT MUTATION

johnmiranda — 2021-01-21 19:19:30 UTC

Does not change the amino acid sequence of a protein.
UUA changed to UUG both will give the amino acid Leucine.

FRAMESHIFT MUTATION

johnmiranda — 2021-01-21 19:19:49 UTC

Changes the entire reading frame of a gene when a base is deleted or inserted.
THE CAT ATE THE RAT
THE ATA TET HER AT

POINT MUTATION

johnmiranda — 2021-01-22 00:49:03 UTC

Involves the substitution, deletion, or insertion of a single base pair.

MISSENSE MUTATION

johnmiranda — 2021-01-22 00:49:30 UTC

Results in an altered amino acid sequence.
Good: This mutation has contributed to a great variety of human antibodies.
Bad: Alcaptonuria, a condition resulting in the accumulation of harmful homogentisic acid due to an altered enzyme that breaks it down.

NONSENSE MUTATION

johnmiranda — 2021-01-22 00:49:49 UTC

Mutation that shortens a protein by introducing a stop codon: UGA, UAA, UAG.

DELETION

johnmiranda — 2021-01-22 01:17:19 UTC

Portion of the chromosome is deleted.

DUPLICATION

johnmiranda — 2021-01-22 01:17:28 UTC

Portion of the chromosome is duplicated

INVERSION

johnmiranda — 2021-01-22 01:17:44 UTC

A portion of the chromosome is broken and re-inserted in the opposite direction.

TRANSLOCATION

johnmiranda — 2021-01-22 01:17:53 UTC

A section of one chromosome breaks and fuses onto another chromosome.

gabrieldossantos2_1 — 2024-05-30 13:00:21 UTC