Research/Library resources by

Staff publications list on PubMed

susanfranks1 — 2022-09-02 15:13:42 UTC

Check out the latest MFT staff publications here!

STAFF PAPER! A combined qSOFA-lactate model for sepsis-related mortality prediction: a small step towards an elusive answer? by Rahuldeb Sarkar

susanfranks1 — 2022-09-02 15:17:26 UTC

Sepsis, or dysregulated host immune response to infection, is a major killer worldwide, responsible for nearly 20% of all deaths globally. Therefore, early identification of patients at increased risk of developing sepsis is important for initiation of appropriate care pathways, and to reduce preventable deaths. However, this identification process requires additional resource allocation, which even high-income countries (HICs) struggle with and contemplate upon.

Efficient prediction tools like the Sequential Organ Failure Assessment (SOFA) score, involving multiple laboratory parameters, have consistently shown high precision, but are challenging to implement in low-income and middle-income countries (LMICs) due to logistical and operational issues. The Sepsis-3 task force showed the quick SOFA (qSOFA) score to have good predictive validity in identifying patients with suspected infection at high risk of mortality in patients outside intensive care units in a HIC setting. This has been subsequently corroborated in LMIC settings.

However, the most recent Surviving Sepsis Guideline strongly recommends against using qSOFA as a single screening tool for sepsis because of low sensitivity.

Therefore, the search for a simplistic effective tool for resource-limited settings continues.

STAFF PAPER! Acupuncture Based on Regulating Autonomic Nerves for the Prevention of Migraine without Aura: A Prospective, Double-Dummy, Randomized Controlled Clinical Trial [Letter] by Mingrui Xie

susanfranks1 — 2022-09-02 15:20:43 UTC

Research & Innovation - interactive graphic

susanfranks1 — 2022-09-02 15:25:26 UTC

Lots of links to useful information and resources...just click on the flashing icons to learn more!

Research & Innovation website

susanfranks1 — 2022-09-02 15:26:41 UTC

Take a look to learn about all aspects of research at MFT

Books, books, books!

susanfranks1 — 2022-09-02 15:29:08 UTC

Check out our collection of books on research - we also cover academic writing, critical appraisal, QI....

Research skills - YouTube

susanfranks1 — 2022-09-02 15:31:25 UTC

Take a look at our YouTube playlist for research skills

The research process at MFT

susanfranks1 — 2022-09-02 15:33:46 UTC

Watch this short video to learn all about the different stages of getting a research idea off the ground and into print

NHS Knowledge & Library Hub

susanfranks1 — 2022-09-02 15:35:56 UTC

Log in with your Athens account for the best experience. You can search across multiple resources and retrieve full text articles where available

Sign up for an OpenAthens account!

susanfranks1 — 2022-09-02 15:37:57 UTC

Registration is easy - use your NHS email for instant access to a wide range of resources including journal articles, e-books and resources such as BMJ Best Practice, and Clinical Skills

susanfranks1 — 2022-09-02 15:39:22 UTC

KLS video

susanfranks1 — 2022-09-02 15:46:42 UTC

Watch our short welcome video to discover more about our service - what can we do for you?

Resources for researchers - Library leaflet

susanfranks1 — 2022-09-06 14:28:34 UTC

Lots of useful links and websites for all things research

STAFF PAPER! Out at the College, by Ginny Bowbrick

susanfranks1 — 2022-09-06 14:36:31 UTC

Ginny Bowbrick talks to the Bulletin about how celebrating our differences is so important for the future of our workforce and how it can ultimately lead to better care for out patients.

JournalTOCs - where researchers keep up to date

susanfranks1 — 2022-10-05 13:12:52 UTC

JournalTOCs is the largest, free collection of scholarly journal Tables of Contents (TOCs): 31,485 journals including 15,083 selected Open Access journals and 11,821 Hybrid journals, from 3333 publishers.

JournalTOCs is for researchers, students, librarians and anyone looking for the latest scholarly articles.
JournalTOCs alerts you when new issues of your Followed journals are published.

STAFF PAPER! A Clinico-Radiographic Study to Gauge the Correlation between the Remaining Interdental Bone Height and Early Site of Furcation Involvement, by Angel Fenol et al

2022-10-06 07:58:27 UTC

Background: Periodontal disease is an inflammatory disease affecting the supporting tissues of teeth; triggered by host response to periodontal pathogens. There occurs connective tissue attachment loss first slowly progressing to alveolar bone loss later on. Early bone loss occurring at the furcal area of multirooted teeth are difficult to diagnose clinically alone. Combination of clinical probing and a diagnostic investigation helps in identifying the early bone loss in such areas much easier. Objective: This study aims to investigate the remaining interdental bone height on mesial and distal sides of maxillary and mandibular permanent first molars and to correlate it with early site of furcation involvement. Materials and methods: Fifty Intraoral Periapical Radiographs (IOPARs) of both maxillary and mandibular permanent first molars of subjects with moderate to severe periodontitis (3-4 millimeters (mm) and >5 mm of clinical attachment loss respectively) were evaluated for remaining interdental bone height on mesial and distal aspects. Clinically, the grade of furcation involvement (grade 1 and early grade 2) was assessed using the Naber’s Probe and radiographically interdental bone loss was assessed. Results: The results show that there is statistically significant involvement of the mesial furcation first when there is distal root displaying bone loss. Also, there is statistically significant involvement of the lingual furcation first when there is mesial root showing more bone loss. Conclusion: Assessment of interdental bone levels using radiographic aids can provide a reliable investigatory method to identify early furcation involvement. A thorough clinical and radiographic examination is essential for a successful treatment outcome.

Knowledge mobilisation

2022-10-06 09:44:23 UTC

Find out if anyone else has had the same research/Qi project idea. If they have, we can put you in touch so you can find out what went well, what didn't, and pick up lots of tips! Watch this short video to find out more.

Staff papers April-September 2022

susanfranks1 — 2022-10-07 12:24:19 UTC

See our top 5 authors and the top 5 articles in journals with the highest impact factor

Staff publications April-September 2022

susanfranks1 — 2022-10-07 12:27:43 UTC

Full report of all staff papers logged for April-September 2022

STAFF PAPER! Effects and Proposed Countermeasures ofAbortion Bans and Restrictions on People With Uteruses and Society, by Oluwateniayo Okpaise et al

susanfranks1 — 2022-10-10 15:00:15 UTC

With the recent overturning of Roe V. Wade by the Supreme Court, access to abortions in many regions across the United States will become very limited as laws regarding fetal termination will be determined by state legislators rather than on a federal level. This article highlights the effects of Roe V. Wade’s abolishment on individuals that can get pregnant, how unwanted pregnancies will affect society in general, and reasonable steps forward following the ban. We conducted an electronic search using PubMed, Google, and Google Scholar. The search was retrospective, and the preliminary results focused on articles about the rationale behind pregnancy termination and the overall effects of abortion and the ban. Review papers, original papers, and newspaper articles were eligible for use. Sample size and region of publication were not exclusionary criteria. Each author independently reviewed and extracted data to write up each assigned section, and group collaborations occurred to create the final draft. Out of the 93 resources reviewed, 32 sources were deemed eligible and used in this article. These resources included 23 journal articles, eight websites, and one book.. The data gathered showed that while abortions have many potential complications even when performed under regulated conditions, taking away the choice of those with a uterus is also not without consequence. The economic, familial, and societal implications should be considered moving forward as safety nets will need to be implemented for people with uterus and children involved.

Improving engagement with research

trustlibrary — 2022-11-02 11:33:59 UTC

Abstract

Background: Increasing pressure to publicise research findings and generate impact, alongside an expectation from funding bodies to go beyond publication within academic journals, has generated interest in alternative methods of science communication. Our aim is to describe our experience of using a variety of creative communication tools, reflect on their use in different situations, enhance learning and generate discussion within the systematic review community.

Methods: Over the last 5 years, we have explored several creative communication tools within the systematic review process and beyond to extend dissemination beyond traditional academic mechanisms. Central to our approach is the co-production of a communication plan with potential evidence users which facilitates (i) the identification of key messages for different audiences, (ii) discussion of appropriate tools to communicate key messages and (iii) exploration of avenues to share them. We aim to involve evidence users in the production of a variety of outputs for each research project cognisant of the many ways in which individuals engage with information.

Results: Our experience has allowed us to develop an understanding of the benefits and challenges of a wide range of creative communication tools. For example, board games can be a fun way of learning, may flatten power hierarchies between researchers and research users and enable sharing of large amounts of complex information in a thought provoking way, but they are time and resource intensive both to produce and to engage with. Conversely, social media shareable content can be quick and easy to produce and to engage with but limited in the depth and complexity of shareable information.

Discussion: It is widely recognised that most stakeholders do not have time to invest in reading large, complex documents; creative communication tools can be a used to improve accessibility of key messages. Furthermore, our experience has highlighted a range of additional benefits of embedding these techniques within our project processes e.g. opening up two-way conversations with end-users of research to discuss the implications of findings.

STAFF PAPER! Development, implementation and evaluation of a seven‑day clinical pharmacy service in a tertiary referral teaching hospital during surge‑2 of the COVID‑19 pandemic, by S Matthews et al

trustlibrary — 2022-11-15 09:01:49 UTC

Abstract Background Seven-day clinical pharmacy services in the acute sector of the National Health Service are limited. There is a paucity of evidential patient beneft. This limits investment and infrastructure, despite United Kingdom wide calls. Aim To optimise medicines seven-days a week during surge-2 of the COVID-19 pandemic through implementation of a seven-day clinical pharmacy service. This paper describes service development, evaluation and sustainability. Setting A tertiary-referral teaching hospital, London, United Kingdom. Development The seven-day clinical pharmacy service was developed to critical care, acute and general medical patients. Clinical leads developed the service specifcation and defned priorities, targeting complex patients and transfer of care. Contributing staf were briefed and training materials developed. Implementation The service was implemented in January 2021 for 11 weeks. Multidisciplinary team communication brought challenges; strategies were employed to overcome these. Evaluation A prospective observational study was conducted in intervention wards over two weekends in February 2021. 1584 beds were occupied and 602 patients included. 346 interventions were reported and rated; 85.6% had high or moderate impact; 56.7% were time-critical. The proportion of medicines reconciliation within 24-h of admission was analysed across the hospital between November 2020 and May 2021. During implementation, patients admitted Friday-Sunday were more likely to receive medicines reconciliation within 24-h (RR 1.41 (95% CI 1.34–1.47), p<0.001). Rostered services were delivered sustainably in terms of shift-fll rate and medicines reconciliation outcome. Conclusion Seven-day clinical pharmacy services beneft patient outcome through early medicines reconciliation and intervention. Investment to permanently embed the service was sustained

STAFF PAPER! Preterm and term pre-eclampsia: Relative burdens of maternal and perinatal complications

trustlibrary — 2023-04-04 08:09:50 UTC

Objective: To determine the relative burdens of maternal and perinatal complica-tions for preterm and term pre-eclampsia.
Design: Prospective observational cohort study.
Setting: Two English maternity units.
Population: Unselected women with singleton pregnancies who developed pre- eclampsia (International Society for the Study of Hypertension in Pregnancy def inition).
Methods: Outcomes were ascertained by health record review and compared be-tween pregnancies with preterm (versus term) pre-eclampsia.
Main outcome measures: Severe maternal hypertension, maternal mortality or major maternal morbidity, perinatal mortality or major neonatal morbidity, neonatal unit (NNU) admission ≥48 hours, and birthweight <3rd percentile.
Results: Among 40 241 singleton pregnancies, 298 (0.7%, 95% confidence interval [CI] 0.66–0.83) and 1194 (3.0%, 95% CI 2.8–3.1) developed preterm and term pre- eclampsia, respectively. Women with preterm (versus term) pre-eclampsia more commonly experienced adverse maternal or perinatal events: severe hypertension 18.5% (95% CI 14.5–23.3) versus 13.6% (95% CI 11.7–15.6); maternal mortality/major morbidity 7.4% (95% CI 4.9–10.9) versus 2.2% (95% CI 1.5–3.2); perinatal mortal-ity/major neonatal morbidity 29.5% (95% CI 24.6–34.9) versus 2.2% (95% CI 1.5– 3.2); and birthweight <3rd percentile 54.4% (95% CI 48.7–59.9) versus 14.2% (95% CI 12.4–16.3). However, in absolute terms, most maternal complications occurred in women with term pre-eclampsia, as did a large proportion of perinatal compli-cations: severe hypertension 74.7% (95% CI 68.5–80.0); maternal mortality/major morbidity 54.2% (95% CI 40.3–67.4); perinatal mortality/major neonatal morbidity 22.8% (95% CI 16.1–31.3); NNU admission ≥48 hours 38.1% (95% CI 32.4–44.1); and birthweight <3rd percentile 51.2% (95% CI 45.8–56.5).
Conclusions: Although adverse event risks are greater with preterm (versus term) pre-eclampsia, term disease is associated with at least equivalent total numbers of maternal, and a significant proportion of perinatal, adverse events. Increased efforts should be made to decrease the incidence of term pre-eclampsia.