https://padlet.com/sarahd59/h3s4uanhgofw2byn Management of patients experiencing GIT and cellular dysfunction en-us 2023-08-27 07:12:24 UTC 2023-08-28 01:18:10 UTC hello@padlet.com sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005979 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005979 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005980 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005980 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005981 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005981 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005982 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005982 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005983 What were your significant risks Tamoxifen? Are you able to group these risks? Why are they significant?
Do you understand the MoA of how the patient might develop the risks?
Did you need to go and look them up again? ]]> 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005983 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005984 How / why does it occur?
What are they and what signs and symptoms would we see?
What do we as nurses do;
- prevent and/ or manage these?]]> 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005984 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005985 Naproxen

Class: NSAID
MOA: Inhibit production of prostaglandins by blocking COX enzymes, reducing inflammation and producing analgesic effects  
Signs and symptoms:
- GIT bleeding 
- NSAID induced renal impairment 
- Increase risk of cardiovascular events 
- Changes in blood pressure 
Drug to drug interactions:
- None on drug chart 
How to prevent, assess or manage risks/nursing considerations:
- Monitor complete blood count to assess kidney and liver function
- Taken with food 
- Use lowest effective dose for the shortest period of time to reduce complications ]]> 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005985 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005986 Tamoxifen
Class:
sex hormone/ cancer treatment
MOA:
Acts  on estrogen receptor sites in breast tissue to stop the growth of tumours growing in breast tissue.
Signs and symptoms:
hot flushes, sweating, vaginal discharge, nausea, oedema,  fatty liver, uterine polyps
Drug to drug interactions:
warfarin - Tamoxifen increases Wararin anticoagulant effect and increases bleeding.
How to prevent, assess or manage risks/nursing considerations:
careful risk assessment should be done by specialist to ensure drug is correct for patient, especially menopause patients as it can cause an increase in endometrial cancer developing.

]]> 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005986 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005987 Panadol Osteo

Class: Analgesic
MOA: inhibits prostaglandin synthesis, provides mild to moderate pain and fever
Signs and symptoms: skin rash, wheezing, tightness in chest, difficulty breathing, swelling, nausea
Drug to drug interactions:
Warfarin, Metoclopramide, Chloraphenicol, Alcohol, Probenecid, Cholestyramine
How to prevent, assess or manage risks/nursing considerations: take with water, can be taken with or without food, caplets must not be crushed, max daily dose (4g), should not be used with other paracetamol-containing drugs ]]> 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005987 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005988 Morphine

Class: opioid analgesic
MOA: Opioid analgesics act on receptors in the CNS and GIT producing analgesia, respiratory depression, sedation and constipation
Signs and symptoms:
- respiratory depression
- blurred visoon
- sedation
- GIT upset
- restlessness
Drug to drug interactions:
- rifampicin (antibiotic) increases metabolism which decreases effect

How to prevent, assess or manage risks/nursing considerations:
- dependence 
- monitor BLs 
- pain assessment 
- monitor mental status 
- monitor for respiratory depression
- use with caution for patients with head injuries 
- take blood pressure before administration
- assistance with mobilisation (falls risk)]]> 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005988 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005989 Esomeprazole

Class: proton pump inhibitors
MOA: Bind to the hydrogen/potassium ATPase enzyme system, inhibiting both stimulated and basal acid secretion.
Signs and symptoms: headache, n + v, diarrhoea, abdo pain, constipation, flatulence
Drug to drug interactions: apalutamide, enzalutamide,
How to prevent, assess or manage risks/nursing considerations: notify doctors if pt develops black stools or vomit that looks like coffee grounds, advice pt to avoid alcohol and foods that cause an increase in GI irritation ]]> 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005989 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005990 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005990 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005991 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005991 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005992 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005992 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005993 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005993 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005994 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005994 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005995 Note: Always consider:
Is there anything in the patient's condition/ past history that may increase the risks?]]> 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005995 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005996 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005996 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005997 Mrs Marple now has constipation. What medication/s will you give her to relieve this?
Deakin Hospital Protocol needs to be considered for this decision]]> 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005997 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005998 What factors may result in impaired medication effects in these patients?]]> 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005998 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005999 Decreased renal and liver function in elderly, so absorption, distribution, metabolism and excretion is inhibited. Therefore, drugs accumulate in their systems longer and at higher levels than younger people. Also altered body composition (more fat, less water), decreased body size. Increases adverse effects of drugs. Polypharmacy causing dehydration and other med errors ]]> 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674005999 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674006000 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674006000 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674006001 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674006001 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674006002 Decrease the body's ability to break down or remove medication from the system due to:
-increased body fat
- decreased body water
-decreased muscle mass
 -changes in renal and liver function]]> 2023-08-27 07:12:24 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674006002 sarahd59 https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674437476 2023-08-28 01:12:43 UTC https://padlet.com/sarahd59/h3s4uanhgofw2byn/wish/2674437476