https://padlet.com/jack_song2/gxix4ohflaoc Jack and Andy en-us 2018-03-13 23:36:32 UTC 2023-05-18 03:18:59 UTC hello@padlet.com jack_song2 https://padlet.com/jack_song2/gxix4ohflaoc/wish/241664711 2018-03-13 23:40:05 UTC https://padlet.com/jack_song2/gxix4ohflaoc/wish/241664711 seongjun_lee https://padlet.com/jack_song2/gxix4ohflaoc/wish/241666507 Yes, because Sam's father had the same type of the cancer with Sam.]]> 2018-03-13 23:51:19 UTC https://padlet.com/jack_song2/gxix4ohflaoc/wish/241666507 seongjun_lee https://padlet.com/jack_song2/gxix4ohflaoc/wish/241667802 'Benign' defines as harmless and 'malignant' defines as dangerous or deadly.]]> 2018-03-13 23:59:01 UTC https://padlet.com/jack_song2/gxix4ohflaoc/wish/241667802 seongjun_lee https://padlet.com/jack_song2/gxix4ohflaoc/wish/241667812 Benign tumor does not affect near by tissues or spread while malignant tumor may be cancerous.]]> 2018-03-13 23:59:06 UTC https://padlet.com/jack_song2/gxix4ohflaoc/wish/241667812 seongjun_lee https://padlet.com/jack_song2/gxix4ohflaoc/wish/241669159 Make someone liable to get a cancer.]]> 2018-03-14 00:08:14 UTC https://padlet.com/jack_song2/gxix4ohflaoc/wish/241669159 seongjun_lee https://padlet.com/jack_song2/gxix4ohflaoc/wish/241669940 People that are predisposed to getting cancer does not definitely get cancer, but is at a higher chance of getting cancer]]> 2018-03-14 00:13:26 UTC https://padlet.com/jack_song2/gxix4ohflaoc/wish/241669940 seongjun_lee https://padlet.com/jack_song2/gxix4ohflaoc/wish/241670686 When we compared Sam's APC sequence to the normal APC sequence, only one base was different. ]]> 2018-03-14 00:17:52 UTC https://padlet.com/jack_song2/gxix4ohflaoc/wish/241670686 seongjun_lee https://padlet.com/jack_song2/gxix4ohflaoc/wish/243273357 One possible consequence is the change of amino acids. The second possible consequence can be no change. The last possible consequence can have a STOP codon in DNA structure. ]]> 2018-03-18 23:17:29 UTC https://padlet.com/jack_song2/gxix4ohflaoc/wish/243273357 seongjun_lee https://padlet.com/jack_song2/gxix4ohflaoc/wish/243273415 Jane and Sam's mutation will decrease the ability of the APC protein to bind to B-catenin..]]> 2018-03-18 23:17:47 UTC https://padlet.com/jack_song2/gxix4ohflaoc/wish/243273415 seongjun_lee https://padlet.com/jack_song2/gxix4ohflaoc/wish/243273424 If the APC gene is damaged, then it will not be able to bind with the B-catenin. If not bound to APC and degraded, B-catenin accumulates and can enter the nucleus and bind to T-cell factor(TCF). Binding to TCF triggers the transcription of genes that promote cell division.]]> 2018-03-18 23:17:51 UTC https://padlet.com/jack_song2/gxix4ohflaoc/wish/243273424 seongjun_lee https://padlet.com/jack_song2/gxix4ohflaoc/wish/243273434 2018-03-18 23:17:55 UTC https://padlet.com/jack_song2/gxix4ohflaoc/wish/243273434 seongjun_lee https://padlet.com/jack_song2/gxix4ohflaoc/wish/243273443 2018-03-18 23:17:59 UTC https://padlet.com/jack_song2/gxix4ohflaoc/wish/243273443 seongjun_lee https://padlet.com/jack_song2/gxix4ohflaoc/wish/243273447 2018-03-18 23:18:02 UTC https://padlet.com/jack_song2/gxix4ohflaoc/wish/243273447 jack_song2 https://padlet.com/jack_song2/gxix4ohflaoc/wish/243276525 Sam's APC protein is much shorter than the normal APC protein.]]> 2018-03-18 23:39:56 UTC https://padlet.com/jack_song2/gxix4ohflaoc/wish/243276525 jack_song2 https://padlet.com/jack_song2/gxix4ohflaoc/wish/243276571 The amino acid changing into a STOP codon is the consequence of the mutation ]]> 2018-03-18 23:40:09 UTC https://padlet.com/jack_song2/gxix4ohflaoc/wish/243276571 jack_song2 https://padlet.com/jack_song2/gxix4ohflaoc/wish/243276694 The DNA may overlap or ]]> 2018-03-18 23:40:57 UTC https://padlet.com/jack_song2/gxix4ohflaoc/wish/243276694