https://padlet.com/ehtikam_hassan/gh80lfjth5m2 WHAT IS SICKLE CELL ANAEMIA? en-us 2018-02-26 14:42:13 UTC 2023-05-19 09:41:46 UTC hello@padlet.com ehtikam_hassan https://padlet.com/ehtikam_hassan/gh80lfjth5m2/wish/236613574 sickle cell anemia is the result of mutant beta globin (HBB; 141900) in which the mutation causes sickling of hemoglobin. 

More common in African .

The alleles for this trait exhibit co-dominance.

Sickle cell disease is an inherited condition. Two genes for the sickle hemoglobin must be inherited from one's parents in order to have the disease. A person who receives a gene for sickle cell disease from one parent and a normal gene from the other has a condition called "sickle cell trait."



]]> 2018-02-28 19:13:31 UTC https://padlet.com/ehtikam_hassan/gh80lfjth5m2/wish/236613574 ehtikam_hassan https://padlet.com/ehtikam_hassan/gh80lfjth5m2/wish/236619926 2018-02-28 19:22:29 UTC https://padlet.com/ehtikam_hassan/gh80lfjth5m2/wish/236619926 ehtikam_hassan https://padlet.com/ehtikam_hassan/gh80lfjth5m2/wish/236708150 Signs and symptoms of sickle cell disease usually begin in early childhood. Characteristic features of this disorder include a low number of red blood cells (anemia), repeated infections, and periodic episodes of pain.]]> 2018-02-28 22:36:07 UTC https://padlet.com/ehtikam_hassan/gh80lfjth5m2/wish/236708150 ehtikam_hassan https://padlet.com/ehtikam_hassan/gh80lfjth5m2/wish/236708257 A genetic blood disorder due to single point mutation. It causes red blood cells to be misshapen.]]> 2018-02-28 22:36:36 UTC https://padlet.com/ehtikam_hassan/gh80lfjth5m2/wish/236708257 ehtikam_hassan https://padlet.com/ehtikam_hassan/gh80lfjth5m2/wish/236708994 Hemoglobin consists of 4 protein subunits, typically, two subunits called alpha-globin and two subunits called beta-globin. The HBB gene provides instructions for making beta-globin. Various versions of beta-globin result from different mutations in the HBB gene. ]]> 2018-02-28 22:40:04 UTC https://padlet.com/ehtikam_hassan/gh80lfjth5m2/wish/236708994