Biochemistry & Blood Sciences - essay plan for assessment 1 by PINNINGTON Aimee https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5 Contributions from group discussion - all posts are anonymous and you can add constructive feedback to other groups, which I encourage you to do! en-us 2022-10-05 11:11:13 UTC 2022-12-16 22:23:01 UTC hello@padlet.com Anaemia https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327389039 2022-10-05 11:14:06 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327389039 AML https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327389310 2022-10-05 11:14:22 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327389310 Daily QCs https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327389541 2022-10-05 11:14:37 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327389541 Diabetes https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327389566 2022-10-05 11:14:38 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327389566 Calibration https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327390069 2022-10-05 11:14:57 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327390069 Internal QC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327390095 2022-10-05 11:14:58 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327390095 Non-alcoholic fatty liver disease https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327390176 2022-10-05 11:15:03 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327390176 UKAS https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327390292 2022-10-05 11:15:09 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327390292 Selection and procurement of POCT equipment https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327390544 2022-10-05 11:15:24 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327390544 Kidney Disease https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327390690 2022-10-05 11:15:31 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327390690 IQC/EQA performance for both lab based and POCT assay https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327390712 2022-10-05 11:15:32 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327390712 https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327390716 Any maintenance that is performed and how this may affect the test/disease?]]> 2022-10-05 11:15:32 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327390716 Cardiovascular disease https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327391127 Diabetes
Cardiovascular disease
PE/DVT]]> 2022-10-05 11:15:53 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327391127 NEQAS https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327391302 2022-10-05 11:16:05 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327391302 COVID https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327393079 2022-10-05 11:17:29 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327393079 https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327393095 Are we supposed to compare the pros/cons of a POC test vs the same in house lab test?]]> 2022-10-05 11:17:30 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327393095 Different methods of testing. Eg. Hb result on lab analyser vs POCT. Any differentials? How is that monitored to ensure no fluctuations in results. https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327393112 2022-10-05 11:17:32 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327393112 Thrombosis https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327393522 D-dimer
PT/INR]]> 2022-10-05 11:17:59 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327393522 Quality of service https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327394111 2022-10-05 11:18:36 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327394111 EQA/IQC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327394123 procedural
COSHH
protocol review
audit
Risk assessment
maintenance]]> 2022-10-05 11:18:37 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327394123 Use of quality management system. https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327394389 Storing of SOPs, previous QC results, batch numbers of QC material, health and safety regs]]> 2022-10-05 11:18:53 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327394389 If a test may not be suitable in other settings/limitations of a test https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327395293 2022-10-05 11:19:46 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327395293 comparing both hospital and POCT quality assurance, pros and cons? https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327395496 2022-10-05 11:19:59 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327395496 Looking at the amount of support from the laboratory to ensure the quality testing and accreditation requirements are met for POCT https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327395811 2022-10-05 11:20:13 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327395811 Comparisons of accuracy, reliability, and timeliness of the test process and results. https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327396017 2022-10-05 11:20:25 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327396017 Analysing point of care testing data can show the quality trends before it can affects results. https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327396616 2022-10-05 11:20:49 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327396616 How good results are and how these can associate with any treatment https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327397717 2022-10-05 11:21:52 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327397717 Service provided, enough? https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327398236 control of the disease
Effectiveness of diagnosis and monitoring
side affects
methodology ]]> 2022-10-05 11:22:13 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327398236 iron deficiency anaemia https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327398337 2022-10-05 11:22:20 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327398337 sickle cell disease https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327399401 2022-10-05 11:23:22 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327399401 Limitations of POCT - less precise and specific compared to a clinical lab setting https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327399422 2022-10-05 11:23:23 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327399422 UKAS AND ISO standards for laboratory testing vs POCT. https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327400082 2022-10-05 11:24:02 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327400082 Annual testing to monitor the progression of the diease (E.g. hypertension, dyslipidaemia, type 2 diabetes using hbA1c for NAFLD) https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327400504 2022-10-05 11:24:27 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327400504 use of uncontrolled equipment https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327401191 2022-10-05 11:25:06 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327401191 is POCT where it can be done at home or where the test is done in front of patient? and if so would sexual health diseases count as people can request at home kits and can have hospital tests too?... https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327401252 2022-10-05 11:25:09 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327401252 Cost per test https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327402284 Some POCT is more expensive per test but required due to speed of results. Can labs afford to provide more point of care testing if the same assay is available in automation for cheaper?]]> 2022-10-05 11:26:03 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327402284 cost effectiveness https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327402486 2022-10-05 11:26:14 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327402486 Clarification community based and hospital based? involving both. https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327402693 Treat like an audit ? review of process and documentation?
How much detail on the actual disease and other aspects?
How to lay out?]]> 2022-10-05 11:26:25 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327402693 https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327403143 Cost, accuracy, speed, availability.]]> 2022-10-05 11:26:50 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327403143 Limitations https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327403867 Harder to control?
Who is carrying out the POCT? Is training sufficient? - is sample quality an issue?
More Expensive?
Often used on an indiviudual basis - less batch work]]> 2022-10-05 11:27:23 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327403867 Strengths https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327404981 Quicker turnaround time
More focused testing
Usually quicker]]> 2022-10-05 11:28:28 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327404981 Sample quality difficult to control as clinical staff sometimes unaware of limitations https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327405984 2022-10-05 11:29:26 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327405984 Can you write about glucose? https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327406090 2022-10-05 11:29:31 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327406090 There isn't a need for highly trained clinical staff to carryout POCT https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327406277 2022-10-05 11:29:41 UTC https://padlet.com/aimeepinnington/g4t9h77rlysdq1l5/wish/2327406277