https://padlet.com/jjones146/g2u7spparjne en-us 2018-04-03 14:48:13 UTC 2026-02-12 14:48:41 UTC hello@padlet.com https://padlet.com/jjones146/g2u7spparjne/wish/248225368 In places which the the disease of malaria is present, the sickle cell anemia is present. this is due to the fact that sickle cell gives organisms an edge against malaria, allowing them to be resistant to malaria. The downside is that you have sickle cell. Therefore being a heterozygote is an advantage because you won't have sickle cell, and you'll still be resistant to malaria.]]> 2018-04-03 17:30:17 UTC https://padlet.com/jjones146/g2u7spparjne/wish/248225368 https://padlet.com/jjones146/g2u7spparjne/wish/248535161 Sickle cell anemia is a genetic disease that prevents oxygen from being transported. Scientist Anthony Allison studied this disease and discovered that there were more cases of sickle cell near coast lines. He found that malaria is connected to sickle cell anemia and near coast lines there are mosquitos that carry malaria parasites. In no malaria areas, sickle cell is chosen against but in areas with malaria people that had sickle cell were given protection against malaria. Heterozygote advantage protects you against malaria and you do not get sickle cell.]]> 2018-04-04 15:11:38 UTC https://padlet.com/jjones146/g2u7spparjne/wish/248535161 https://padlet.com/jjones146/g2u7spparjne/wish/248535533 In areas where malaria is more common, more people have sickle cell anemia. In an experiment done by Mr. Allison, he realized that people with sickle cell anemia had less parasites then those without. He eventually came up with the conclusion that people without sickle (and not carriers) were most vulnerable to malaria, and people who were carriers had a resistance to malaria.]]> 2018-04-04 15:12:06 UTC https://padlet.com/jjones146/g2u7spparjne/wish/248535533 https://padlet.com/jjones146/g2u7spparjne/wish/248535661 2018-04-04 15:12:17 UTC https://padlet.com/jjones146/g2u7spparjne/wish/248535661 https://padlet.com/jjones146/g2u7spparjne/wish/248535777 In areas of Africa where there are high incidents of sickle cell anemia there are also high incidents of malaria. People that did not have sickle cell genes are more likely to get malaria. Carriers of the sickle cell gene have resistance  to malaria. This is due to the fact that carriers of the sickle cell gene had a lower parasite count, so as evolution occurred, through mutation, the sickle gene became protected from malaria. ]]> 2018-04-04 15:12:32 UTC https://padlet.com/jjones146/g2u7spparjne/wish/248535777 https://padlet.com/jjones146/g2u7spparjne/wish/248536022 Sickle cell anemia is a genetic disease where the red blood cells in a human become misshapen. This disease is particular among African descent. A scientist discovered that sickle cell anemia and malaria were directly related. Where there was a truly high incidence of sickle cell, there was a high incidence of malaria. They discovered that if the parents were both heterozygous, the odds of 1/4 sickle cell homozygous, 2/4 heterozygous, & 1/4 normal. The absence of malaria would create a strong selection against the sickle gene; however, in a malarial environment, individuals born with 2 copies of the sickle cel gene and those born with 2 copies of the normal gene are both at a disadvantage - 1 gets sickle, 1 vulnerable to malaria.]]> 2018-04-04 15:13:00 UTC https://padlet.com/jjones146/g2u7spparjne/wish/248536022 https://padlet.com/jjones146/g2u7spparjne/wish/248536562 When you have one sickle cell and one non affected (heterozygous); there is a higher immunity to malaria. Being a carrier because of heterozygote you don't have sickle cell anemia and you will be resistant to malaria. I would like to learn what other genetic and infectious diseases are linked. I'd also like to learn how we can use being a carrier of sickle cell anemia as an antibiotic and medicine to malaria. ]]> 2018-04-04 15:14:01 UTC https://padlet.com/jjones146/g2u7spparjne/wish/248536562 islam21 https://padlet.com/jjones146/g2u7spparjne/wish/248536589 In areas where malaria is more common, there is also a strong presence of sickle cell anemia. Both diseases are frequent near places with large bodies of water. The heterozygote advantage in that area is that the carriers of sickle cell anemia (since it's recessive) are resistant to malaria but still carry the disease, so they aren't affected by it. If the person is homozygous, they have either no resistance to malaria or are affected by sickle cell anemia. ]]> 2018-04-04 15:14:03 UTC https://padlet.com/jjones146/g2u7spparjne/wish/248536589 https://padlet.com/jjones146/g2u7spparjne/wish/248537012 Those who are either a carrier for or are affected by Sickle Cell Anemia have an innate resistance to Malaria. However, those with Sickle Cell Anemia were unlikely to live to adulthood. However, in areas with lots of mosquitos that carry Malaria, those who are either a carrier for or are affected by Sickle Cell Anemia have a higher chance of surviving in these areas. Thus, in areas with a high incidence of Malaria, those who are heterozygous for Sickle Cell Anemia are positively selected for. ]]> 2018-04-04 15:14:55 UTC https://padlet.com/jjones146/g2u7spparjne/wish/248537012 https://padlet.com/jjones146/g2u7spparjne/wish/248537127 Tony Allison discovered that where there was malaria, there was sickle cell. He found out that sickle cell is able to resist malaria, which is a benefit, however sickle cell is still a genetic disease. Being heterozygote is beneficial because it will help you resist malaria and sickle cell.]]> 2018-04-04 15:15:11 UTC https://padlet.com/jjones146/g2u7spparjne/wish/248537127 https://padlet.com/jjones146/g2u7spparjne/wish/248537213 Sickle Cell Anemia gives an advantage to people heterozygous for it who live in areas where malaria is common. A person carrying one gene for it has a resistance to malaria without getting the full disease, but someone homozygous not for it will not be protected and someone homozygous for it will get the full effects of the disease. I would like to learn if there are other diseases like this that can actually prove an advantage in certain situations. ]]> 2018-04-04 15:15:20 UTC https://padlet.com/jjones146/g2u7spparjne/wish/248537213 schetw21 https://padlet.com/jjones146/g2u7spparjne/wish/248537227 Sickle cell anemia is prevalent in regions where malaria is prevalent as well. Sickle cell anemia provides resistance against the infection of malaria. If one is a carrier for sickle cell anemia, they do not have sickle cell anemia but are still resistant to malaria, making it the ideal genotype in these regions where malaria is prevalent.]]> 2018-04-04 15:15:22 UTC https://padlet.com/jjones146/g2u7spparjne/wish/248537227 https://padlet.com/jjones146/g2u7spparjne/wish/248538108 Sickle cell anemia, in some amount is able to combat against malaria, giving the person some resistance to malaria. However, if the person is homozygous for sickle cell anemia, then they will just be anemic and die from anemia. However, if the person is homozygous for normal blood cells, then they will get malaria easier. Therefore, the heterozygote has the advantage because they possess both the normal blood cell gene and the sickle cell gene , allowing for the person to combat against malaria without getting sickle cell malaria. This is why the map of malaria and sickle cell anemia coincide.

]]> 2018-04-04 15:17:20 UTC https://padlet.com/jjones146/g2u7spparjne/wish/248538108 https://padlet.com/jjones146/g2u7spparjne/wish/248538650 Sickle Cell Anemia is a genetic disease that prevents oxygen from being transported. Often those with this disease do not live long. Sickle Cell Anemia also has the ability to block malaria from infecting the person who has Sickle Cell Anemia. It is advantageous to be both have the dominant gene which prevents the Sickle Cell Anemia from affecting the person, but also have the receive gene preventing the infection of malaria.]]> 2018-04-04 15:18:32 UTC https://padlet.com/jjones146/g2u7spparjne/wish/248538650 https://padlet.com/jjones146/g2u7spparjne/wish/248539387 Sickle Cell Anemia is a genetic disease compared to Malaria being an infectious disease. In places where Malaria exists, typically in Africa, the people who are heterozygous for Sickle Cell Anemia are positively selected for. Sickle Cell Anemia causes resistance against Malaria.]]> 2018-04-04 15:20:07 UTC https://padlet.com/jjones146/g2u7spparjne/wish/248539387