Alexandria Turner by Alexandria Turner https://padlet.com/atturner01/fup9j5mwvkxxo0n1 Sickle Cell Anemia en-us 2020-07-20 01:05:41 UTC 2025-06-27 14:22:53 UTC hello@padlet.com Sickle cell disease is a disorder that affects hemoglobin, the molecule in red blood cells that delivers oxygen to cells in the body. People with this disorder have atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape. atturner01 https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/657998128 2020-07-20 01:32:33 UTC https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/657998128 People with this disorder have atypical hemoglobin molecules, referred to as Hemoglobin S, which can distort the cells into a sickle shape. atturner01 https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/657998963 2020-07-20 01:33:41 UTC https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/657998963 When red blood cells sickle, they break down prematurely, which can lead to anemia, which can cause shortness of breath, fatigue, and inhibit growth in young children. atturner01 https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/658000659 2020-07-20 01:36:00 UTC https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/658000659 Episodes can occur when sickled cells, which are stiff and inflexible, get stuck in small blood vessels and restrict blood flow to organs, causing swelling and pain. atturner01 https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/658002030 2020-07-20 01:37:42 UTC https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/658002030 It is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. Each parent carries one copy of the mutated gene, but typically do not show signs and symptoms of the condition. atturner01 https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/658003921 2020-07-20 01:39:51 UTC https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/658003921 Mutations in the HBB gene cause Sickle Cell Disease. atturner01 https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/658005164 2020-07-20 01:41:31 UTC https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/658005164 Treatments might include medications and blood transfusions. For some children and teenagers, a stem cell transplant might cure the disease. atturner01 https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/658007788 2020-07-20 01:45:00 UTC https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/658007788 atturner01 https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/658012170 2020-07-20 01:50:36 UTC https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/658012170 atturner01 https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/658016517 2020-07-20 01:55:23 UTC https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/658016517 atturner01 https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/658017399 2020-07-20 01:56:24 UTC https://padlet.com/atturner01/fup9j5mwvkxxo0n1/wish/658017399