Coimbra3: A new research group plan to carry out vasectomy surgery on 10 mice, as part of their GA breeding program by Paul Flecknell https://padlet.com/ratvet/Coimbra3 When could pain and distress occur, what measures would you propose to prevent or alleviate pain? en-us 2020-11-17 17:43:28 UTC 2026-03-17 08:36:03 UTC hello@padlet.com https://padlet.net/icons/png/1f42d.png Alterations in their enviroment https://padlet.com/ratvet/Coimbra3/wish/936802712 2020-11-18 14:26:35 UTC https://padlet.com/ratvet/Coimbra3/wish/936802712 handling https://padlet.com/ratvet/Coimbra3/wish/936808367 2020-11-18 14:27:33 UTC https://padlet.com/ratvet/Coimbra3/wish/936808367 restraint https://padlet.com/ratvet/Coimbra3/wish/936809416 2020-11-18 14:27:43 UTC https://padlet.com/ratvet/Coimbra3/wish/936809416 The protocol has been used before? https://padlet.com/ratvet/Coimbra3/wish/936812544 2020-11-18 14:28:13 UTC https://padlet.com/ratvet/Coimbra3/wish/936812544 Handling https://padlet.com/ratvet/Coimbra3/wish/936816000 2020-11-18 14:28:44 UTC https://padlet.com/ratvet/Coimbra3/wish/936816000 Habituation https://padlet.com/ratvet/Coimbra3/wish/936816863 2020-11-18 14:28:52 UTC https://padlet.com/ratvet/Coimbra3/wish/936816863 Surgery https://padlet.com/ratvet/Coimbra3/wish/936818049 2020-11-18 14:29:03 UTC https://padlet.com/ratvet/Coimbra3/wish/936818049 Is the animal used to the investigator? https://padlet.com/ratvet/Coimbra3/wish/936818430 2020-11-18 14:29:06 UTC https://padlet.com/ratvet/Coimbra3/wish/936818430 Analgesia https://padlet.com/ratvet/Coimbra3/wish/936825530 2020-11-18 14:30:13 UTC https://padlet.com/ratvet/Coimbra3/wish/936825530 Short period interventions https://padlet.com/ratvet/Coimbra3/wish/936826484 2020-11-18 14:30:23 UTC https://padlet.com/ratvet/Coimbra3/wish/936826484 positive reinforcement https://padlet.com/ratvet/Coimbra3/wish/936827841 2020-11-18 14:30:35 UTC https://padlet.com/ratvet/Coimbra3/wish/936827841 When did the animals arrive at the housing facility? https://padlet.com/ratvet/Coimbra3/wish/936833918 2020-11-18 14:31:41 UTC https://padlet.com/ratvet/Coimbra3/wish/936833918 What are the characteristics of the animals? Strain, weight, time of their arrival at the facilities? https://padlet.com/ratvet/Coimbra3/wish/936833941 2020-11-18 14:31:41 UTC https://padlet.com/ratvet/Coimbra3/wish/936833941 Since the animal are going through surgery the health screening must be checked (heart rate, respiratory rate, coat condition, etc) https://padlet.com/ratvet/Coimbra3/wish/936841075 2020-11-18 14:32:54 UTC https://padlet.com/ratvet/Coimbra3/wish/936841075 Severe procedure https://padlet.com/ratvet/Coimbra3/wish/936842603 2020-11-18 14:33:10 UTC https://padlet.com/ratvet/Coimbra3/wish/936842603 Transportation and acclimatization https://padlet.com/ratvet/Coimbra3/wish/936843473 2020-11-18 14:33:18 UTC https://padlet.com/ratvet/Coimbra3/wish/936843473 https://padlet.com/ratvet/Coimbra3/wish/936844397 What is the goal of this project, from the scientific point of view?

]]> 2020-11-18 14:33:27 UTC https://padlet.com/ratvet/Coimbra3/wish/936844397 several injections https://padlet.com/ratvet/Coimbra3/wish/936845456 2020-11-18 14:33:37 UTC https://padlet.com/ratvet/Coimbra3/wish/936845456 What is the result of clinical examination (physical examination, heart rate, respiratory rate, coat condition and appearance) https://padlet.com/ratvet/Coimbra3/wish/936850473 2020-11-18 14:34:30 UTC https://padlet.com/ratvet/Coimbra3/wish/936850473 What analgesic or anaestetic will be used? https://padlet.com/ratvet/Coimbra3/wish/936850568 2020-11-18 14:34:31 UTC https://padlet.com/ratvet/Coimbra3/wish/936850568 Can the animal be kept in group or have to be isolated? https://padlet.com/ratvet/Coimbra3/wish/936851409 2020-11-18 14:34:40 UTC https://padlet.com/ratvet/Coimbra3/wish/936851409 loss of effect of the anesthesia/analgesia https://padlet.com/ratvet/Coimbra3/wish/936851499 2020-11-18 14:34:41 UTC https://padlet.com/ratvet/Coimbra3/wish/936851499 husbandry conditions https://padlet.com/ratvet/Coimbra3/wish/936852459 2020-11-18 14:34:51 UTC https://padlet.com/ratvet/Coimbra3/wish/936852459 Some procedures https://padlet.com/ratvet/Coimbra3/wish/936853197 2020-11-18 14:34:58 UTC https://padlet.com/ratvet/Coimbra3/wish/936853197 https://padlet.com/ratvet/Coimbra3/wish/936858205 What are the secondary effects after the surgery?]]> 2020-11-18 14:35:49 UTC https://padlet.com/ratvet/Coimbra3/wish/936858205 Does the project license cover the procedure? https://padlet.com/ratvet/Coimbra3/wish/936860964 2020-11-18 14:36:14 UTC https://padlet.com/ratvet/Coimbra3/wish/936860964 Have the procedure been approved by the ORBEA/DGAV? https://padlet.com/ratvet/Coimbra3/wish/936862736 2020-11-18 14:36:30 UTC https://padlet.com/ratvet/Coimbra3/wish/936862736 Has the protocol been approved by the animal wellfare body https://padlet.com/ratvet/Coimbra3/wish/936865366 2020-11-18 14:36:56 UTC https://padlet.com/ratvet/Coimbra3/wish/936865366 What will be the surgical approach - transabdominal (via laparotomy) or by scrotothomy (through a scrotum incision)? https://padlet.com/ratvet/Coimbra3/wish/936866563 2020-11-18 14:37:09 UTC https://padlet.com/ratvet/Coimbra3/wish/936866563 Post-surgical complications https://padlet.com/ratvet/Coimbra3/wish/936866749 2020-11-18 14:37:11 UTC https://padlet.com/ratvet/Coimbra3/wish/936866749 https://padlet.com/ratvet/Coimbra3/wish/936867513 Can you send the project documents that you submitted for approval?]]> 2020-11-18 14:37:19 UTC https://padlet.com/ratvet/Coimbra3/wish/936867513 if possible perform the scrotum incision than the abdominal surgery https://padlet.com/ratvet/Coimbra3/wish/936869028 2020-11-18 14:37:35 UTC https://padlet.com/ratvet/Coimbra3/wish/936869028 not acclimatized with the facility or handlers https://padlet.com/ratvet/Coimbra3/wish/936874988 2020-11-18 14:38:38 UTC https://padlet.com/ratvet/Coimbra3/wish/936874988 continuous observation of the pain and distress signals of the animals https://padlet.com/ratvet/Coimbra3/wish/936875388 2020-11-18 14:38:42 UTC https://padlet.com/ratvet/Coimbra3/wish/936875388 Lack of environmental enrichment https://padlet.com/ratvet/Coimbra3/wish/936878698 2020-11-18 14:39:18 UTC https://padlet.com/ratvet/Coimbra3/wish/936878698 doses of analgesic and administration time https://padlet.com/ratvet/Coimbra3/wish/936878857 2020-11-18 14:39:20 UTC https://padlet.com/ratvet/Coimbra3/wish/936878857 Enrichment https://padlet.com/ratvet/Coimbra3/wish/936880969 2020-11-18 14:39:42 UTC https://padlet.com/ratvet/Coimbra3/wish/936880969 Score sheets to evaluate pain and distress beatrizrdias0 https://padlet.com/ratvet/Coimbra3/wish/936881674 2020-11-18 14:39:49 UTC https://padlet.com/ratvet/Coimbra3/wish/936881674 Post-surgical handling https://padlet.com/ratvet/Coimbra3/wish/936882139 2020-11-18 14:39:54 UTC https://padlet.com/ratvet/Coimbra3/wish/936882139 Post-operation recovery measures (incubation in the warm place) https://padlet.com/ratvet/Coimbra3/wish/936883468 2020-11-18 14:40:07 UTC https://padlet.com/ratvet/Coimbra3/wish/936883468 Isolation https://padlet.com/ratvet/Coimbra3/wish/936886650 2020-11-18 14:40:41 UTC https://padlet.com/ratvet/Coimbra3/wish/936886650 Increase environmental enrichment https://padlet.com/ratvet/Coimbra3/wish/936892151 2020-11-18 14:41:37 UTC https://padlet.com/ratvet/Coimbra3/wish/936892151 animal training https://padlet.com/ratvet/Coimbra3/wish/936894343 2020-11-18 14:41:58 UTC https://padlet.com/ratvet/Coimbra3/wish/936894343 Will the mice be aware or have clinical signs of having gone through a vasectomy? https://padlet.com/ratvet/Coimbra3/wish/936899299 2020-11-18 14:42:50 UTC https://padlet.com/ratvet/Coimbra3/wish/936899299 Post-procedure supplementation of diet https://padlet.com/ratvet/Coimbra3/wish/936914012 2020-11-18 14:45:20 UTC https://padlet.com/ratvet/Coimbra3/wish/936914012 https://padlet.com/ratvet/Coimbra3/wish/936914626 Acclimatisation]]> 2020-11-18 14:45:27 UTC https://padlet.com/ratvet/Coimbra3/wish/936914626 Using proper monitorization of temperature, respiration and fluid administration? https://padlet.com/ratvet/Coimbra3/wish/936916018 2020-11-18 14:45:42 UTC https://padlet.com/ratvet/Coimbra3/wish/936916018 Were there 3R measures implemented in the procedure? https://padlet.com/ratvet/Coimbra3/wish/936917442 2020-11-18 14:45:58 UTC https://padlet.com/ratvet/Coimbra3/wish/936917442 Using heating pads during surgery https://padlet.com/ratvet/Coimbra3/wish/936919818 2020-11-18 14:46:24 UTC https://padlet.com/ratvet/Coimbra3/wish/936919818 How long does the surgery normaly takes? https://padlet.com/ratvet/Coimbra3/wish/936920988 2020-11-18 14:46:36 UTC https://padlet.com/ratvet/Coimbra3/wish/936920988 Tagging of the animals? https://padlet.com/ratvet/Coimbra3/wish/936929008 2020-11-18 14:48:00 UTC https://padlet.com/ratvet/Coimbra3/wish/936929008 Let mice recover in a heating incubator https://padlet.com/ratvet/Coimbra3/wish/937082590 2020-11-18 15:14:00 UTC https://padlet.com/ratvet/Coimbra3/wish/937082590