Leukemia by Emma Gaskins

LEUKEMIA

caleemcclellan — 2014-10-31 18:28:48 UTC

by Emma Gaskins and Calee McClellan

Internal signals affecting cell cycle

caleemcclellan — 2014-10-31 18:30:26 UTC

The cell cycle is controlled by three internal checkpoints, these checkpoints evaluate the cells condition and genetic information.

These three checkpoints occur near the end of G1, at the G2 transition into M, and during metaphase.

External signals effecting the cell

caleemcclellan — 2014-10-31 18:44:28 UTC

External factors can influence the cell cycle by starting cell division. The death of cells or the presence or lack of hormones can effect the cells cycle: the release or lack of hormones can inhibit cell division. Cell growth initiates cell division because cells must divide as the surface volume ratio increases; cell crowding inhibits cell division.

Organs/organ systems Leukemia affects

caleemcclellan — 2014-10-31 18:56:06 UTC

Once Leukemia starts in the bone marrow and spreads through the blood stream, the Cardiovascular and Hematologic systems are affected (both systems deal with blood).

How Leukemia begins

emmagaskins — 2014-11-02 17:07:05 UTC

With Leukemia, cancerous cells start to develop in the bone marrow. There are two major types of this cancer in the bone marrow: lymphocytic leukemia, when the bone marrow cells that are supposed to form the white blood cells are affected and myelogenous leukemia, when the bone marrow cells responsible for forming the red blood cells are affected. Then, just like any cancerous cells, the cancerous blood cells reproduce and spread through the blood stream.

Symptoms

emmagaskins — 2014-11-02 17:32:57 UTC

Symptoms for Leukemia may vary, but the most common symptoms are headaches, fever, bruising, lack of appetite, swollen spleen or lymph nodes, pain located in the joints, fatigue and unexplained weight loss.

Is Leukemia genetic?

emmagaskins — 2014-11-02 17:40:50 UTC

Leukemia is not hereditary or inherited genetically, though genetics and heredity can contribute to causing leukemia. Therefore, people related to someone suffering from Leukemia have a higher chance of the disease.

Prognosis

emmagaskins — 2014-11-03 01:23:42 UTC

For Chronic Myeloid Leukemia, people in early stages may have a life expectancy of 98 months, and late stage patients may live for 42 months.

People with Acute Myeloid Leukemia have a 20% to 40% chance of survival rate for at least 60 months.

Chronic Lymphocytic Leukemia progresses slowly. If the B-cells are affected, then life expectancy can be anywhere between 10 to 20 years.

Acute Lymphocytic Leukemia is common mainly among children and is treated with chemotherapy. Children have an 80% chance of survival, while adults have a 40% chance.

Symptoms Picture

emmagaskins — 2014-11-03 19:45:31 UTC

Leukemic Blood Cells

emmagaskins — 2014-11-03 19:49:32 UTC

Leukemia in Bone Marrow

emmagaskins — 2014-11-03 19:51:52 UTC