JC2: Genealogy Questions by Sarah I Bases https://padlet.com/sbases1/eryrj5s6aix9rs2k What do you think? en-us 2022-09-21 15:37:06 UTC 2026-01-13 18:14:36 UTC hello@padlet.com https://padlet.net/icons/png/1f914.png Genes Genes Genes https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317595863 Yes, I think it is interesting to learn about who we are. Although there are privacy issues, consumers should be made aware of these possible data breaches and know of the risks. ]]> 2022-09-28 14:17:33 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317595863 https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317597109 I would still participate (and have already) because I am a very curious person that would love to learn the information gained from these companies. Additionally, I feel like in our age of technology we do not have much privacy anyways so might as well learn more about my ancestry if privacy is already a risk anyways. ]]> 2022-09-28 14:18:11 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317597109 https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317598421 I would still do 23andMe and Ancestry, but would not do GEDMatch or similar companies. The lack of database protection to opt for a simple genealogical analysis is not something I trust from GEDMatch.]]> 2022-09-28 14:18:53 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317598421 https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317598451 I would still participate in 23 and Me. I am not afraid of getting convicted of a crime and if any of my family members did I would want them to get convicted as well]]> 2022-09-28 14:18:54 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317598451 Maybe https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317598635 I might still participate in a genealogy database, I would have to look specifically into the policy and privacy standards of whichever company I was considering using to access my genetic information ]]> 2022-09-28 14:18:59 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317598635 https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317598683 I don’t think it would change if I participated in a genealogy database, but it definitely makes me consider it more carefully. It doesn’t seem there are enough privacy factors in place]]> 2022-09-28 14:19:00 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317598683 https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317599277 Yes, but only if it’s a private database. Since only DTC uploads would be allowed on the database, I would trust that only real data is being uploaded.]]> 2022-09-28 14:19:18 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317599277 Yes https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317601159 Knowing what I know now, I would take part in this. I think it’s beneficial to know your background and I believe the risks aren’t too bad for me to not want to do this. There are risks for everything in life. I think it depends on how much one wants to know about their DNA.

]]> 2022-09-28 14:20:19 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317601159 https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317602159 1. Yes, I would still participate. I know the risks but am still interested in what my genome has to tell me.
2. I would keep them transparently aware of potential data breaches, especially if my budget was too thin to cover all forms of protection. ]]> 2022-09-28 14:20:41 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317602159 https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317602678 1. I would probably participate but have done a lot more research into how data breaching occurs and what different companies do to limit these occurrences. It would have been nice if 23andMe had provided information about these issues to consumers or any other DTC companies for that matter ]]> 2022-09-28 14:20:59 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317602678 https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317603322 I don’t think that I would upload my genomic information to a public database like GEDmatch. It doesn’t seem like the privacy of participants who upload their data onto their website is a priority. Privacy concerns outweigh the service that GEDmatch provides. ]]> 2022-09-28 14:21:19 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317603322 https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317603470 I don’t mind using or not using it. I think that based on these papers and presentation, I wouldn’t necessarily want to participate in a database such as GEDmatch because of their phase-unaware detection methods, so I might use a different one, such as 23&me but not in order to find relatives.]]> 2022-09-28 14:21:23 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317603470 1. I would not participate in these public databases like GED match, until better encryption is put in place. https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317605808 2. I think if just limiting the interface and information available to the user would be a great inhibitor to hackers etc.]]> 2022-09-28 14:22:37 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317605808 I would let the world see my genome! https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317606791 not worried about crime for me or my family.
health risks are a bit more of an issue but.. complex traits.. not sure how much information would be useful

]]> 2022-09-28 14:23:08 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317606791 https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317609608 Block uploads of publicly available genomes]]> 2022-09-28 14:24:32 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317609608 Require a cryptographic signature because it protects against tiling, probing, and baiting so it’s the most efficient. https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317609870 2022-09-28 14:24:40 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317609870 https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317610267 I would require a cryptographic signature, because it is the most effective in protection. Although it might be the most expensive, it could bring in more customers who we’ve gained the trust of.]]> 2022-09-28 14:24:52 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317610267 https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317610837 I would block uploads with long runs of heterozygosity. We’ve already discussed in class that we are homozygous at most SNPs. ]]> 2022-09-28 14:25:08 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317610837 use phase-aware algorithms https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317611205 2022-09-28 14:25:16 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317611205 https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317611324 I would definitely try to use my funds to require cryptographic signatures since it protects against tiling, probing, and baiting, so even if it cost more than some other methods it would probably be simpler than trying to combine methods in order to allow for the same coverage ]]> 2022-09-28 14:25:20 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317611324 https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317611796 If I was the CEO of a company like 23 and me I would use cryptographic signature. This would possibly bring more customers to try 23 and me, since they feel more secure.]]> 2022-09-28 14:25:34 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317611796 https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317612998 2. I would look over different methods that would help with data breaches and use the one that would best limit breaches within our company. Also just being honest with customers up front of the possibility of data breach. If I had a budget to worry about I’d have to choose the cheapest but most reliable method. ]]> 2022-09-28 14:26:06 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317612998 2. https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317614447 I’d ensure only our own DTC data, straight from the spit tube, to the lab, to the computer, ends up in our databases. You can’t put fake DNA into the spit tube, the lab would probably return some weird failed result. Then, I’d only allow internal company access to the database. Don’t allow the typical customer to see the exact genotypes or segments of chromosomes where they could be related to people, just report that they seem to be related to person X.]]> 2022-09-28 14:26:46 UTC https://padlet.com/sbases1/eryrj5s6aix9rs2k/wish/2317614447