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      <title>Timeline: Understanding Secondary Hemostasis - Coagulation Cascade Pathways (klineav) by </title>
      <link>https://padlet.com/klineav/ef0fz9d2burbun5h</link>
      <description>Explore the intricate sequence of events in the coagulation cascade through its three main pathways: Intrinsic, Extrinsic, and Common Pathway.</description>
      <language>en-us</language>
      <pubDate>2025-03-23 23:10:23 UTC</pubDate>
      <lastBuildDate>2025-03-23 23:20:31 UTC</lastBuildDate>
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         <title>Prothrombin Activation</title>
         <author>schollli3</author>
         <link>https://padlet.com/klineav/ef0fz9d2burbun5h/wish/3378374502</link>
         <description><![CDATA[The prothrombinase complex converts prothrombin (Factor II) to thrombin (Factor IIa). This reaction requires calcium ions and phospholipid surfaces.]]></description>
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         <pubDate>2025-03-23 23:10:23 UTC</pubDate>
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         <title>Prothrombinase Complex Formation</title>
         <author>schollli3</author>
         <link>https://padlet.com/klineav/ef0fz9d2burbun5h/wish/3378374503</link>
         <description><![CDATA[Factor Xa combines with Factor Va on phospholipid surfaces in the presence of calcium to form the prothrombinase complex.]]></description>
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         <pubDate>2025-03-23 23:10:23 UTC</pubDate>
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         <title>Initial Contact Activation</title>
         <author>schollli3</author>
         <link>https://padlet.com/klineav/ef0fz9d2burbun5h/wish/3378374504</link>
         <description><![CDATA[The intrinsic pathway begins when blood contacts a negatively charged surface, activating Factor XII to XIIa. This process requires no tissue damage.]]></description>
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         <pubDate>2025-03-23 23:10:23 UTC</pubDate>
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         <title>Factor X Activation</title>
         <author>schollli3</author>
         <link>https://padlet.com/klineav/ef0fz9d2burbun5h/wish/3378374505</link>
         <description><![CDATA[The TF-VIIa complex, in the presence of calcium and phospholipids, activates Factor X to Xa, leading to the common pathway.]]></description>
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         <pubDate>2025-03-23 23:10:23 UTC</pubDate>
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         <title>Tissue Factor Exposure</title>
         <author>schollli3</author>
         <link>https://padlet.com/klineav/ef0fz9d2burbun5h/wish/3378374506</link>
         <description><![CDATA[The extrinsic pathway initiates when tissue damage exposes tissue factor (TF/Factor III) to the bloodstream.]]></description>
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         <pubDate>2025-03-23 23:10:23 UTC</pubDate>
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         <title>Cross-linked Fibrin Clot</title>
         <author>schollli3</author>
         <link>https://padlet.com/klineav/ef0fz9d2burbun5h/wish/3378374507</link>
         <description><![CDATA[Thrombin activates Factor XIII to XIIIa, which creates strong covalent bonds between fibrin molecules, forming a stable cross-linked fibrin clot.]]></description>
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         <pubDate>2025-03-23 23:10:23 UTC</pubDate>
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         <title> Fibrinogen to Fibrin Conversion</title>
         <author>schollli3</author>
         <link>https://padlet.com/klineav/ef0fz9d2burbun5h/wish/3378374508</link>
         <description><![CDATA[Thrombin converts fibrinogen (Factor I) to fibrin monomers, which begin to form loose connections.]]></description>
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         <pubDate>2025-03-23 23:10:23 UTC</pubDate>
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         <title>Factor X Activation Complex Formation</title>
         <author>schollli3</author>
         <link>https://padlet.com/klineav/ef0fz9d2burbun5h/wish/3378374509</link>
         <description><![CDATA[Factor IXa combines with Factor VIIIa on phospholipid surfaces in the presence of calcium to form the 'tenase complex' which activates Factor X to Xa. This is a crucial bridge to the common pathway.]]></description>
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         <pubDate>2025-03-23 23:10:23 UTC</pubDate>
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         <title>Factor XI Activation</title>
         <author>schollli3</author>
         <link>https://padlet.com/klineav/ef0fz9d2burbun5h/wish/3378374510</link>
         <description><![CDATA[Activated Factor XIIa converts Factor XI to XIa. This step requires calcium ions (Ca2+) as a cofactor.]]></description>
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         <pubDate>2025-03-23 23:10:23 UTC</pubDate>
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         <title> Factor VII Activation</title>
         <author>schollli3</author>
         <link>https://padlet.com/klineav/ef0fz9d2burbun5h/wish/3378374512</link>
         <description><![CDATA[Tissue Factor combines with Factor VII, converting it to Factor VIIa. This process requires calcium ions.]]></description>
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         <pubDate>2025-03-23 23:10:23 UTC</pubDate>
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         <title>Factor IX Activation</title>
         <author>schollli3</author>
         <link>https://padlet.com/klineav/ef0fz9d2burbun5h/wish/3378374513</link>
         <description><![CDATA[Factor XIa activates Factor IX to IXa, another calcium-dependent step in the cascade.]]></description>
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         <pubDate>2025-03-23 23:10:23 UTC</pubDate>
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