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      <title>Immune Response to  the Chikungunya Virus by Emily Coulter</title>
      <link>https://padlet.com/coulterek/dgdycnbzjnm6</link>
      <description>Half of the immune response was virtually impossible to find so I used my imagination</description>
      <language>en-us</language>
      <pubDate>2019-03-03 21:20:48 UTC</pubDate>
      <lastBuildDate>2026-01-25 16:54:47 UTC</lastBuildDate>
      <webMaster>hello@padlet.com</webMaster>
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         <title>Step ONE:
Contraction</title>
         <author>coulterek</author>
         <link>https://padlet.com/coulterek/dgdycnbzjnm6/wish/337278861</link>
         <description><![CDATA[<div>The act that kicks off the infection of the Chikungunya virus is getting bitten by a mosquito. Mosquitoes are known to carry a lot of viruses, it just so happens that Chikungunya is one of them. Since the mosquito pearces the skin, this is how the virus overcomes the external barrier of skin.</div>]]></description>
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         <pubDate>2019-03-03 21:30:00 UTC</pubDate>
         <guid>https://padlet.com/coulterek/dgdycnbzjnm6/wish/337278861</guid>
      </item>
      <item>
         <title>Step TWO: Breaking In</title>
         <author>coulterek</author>
         <link>https://padlet.com/coulterek/dgdycnbzjnm6/wish/337279203</link>
         <description><![CDATA[<div>The Chikingunya virus is of course... a virus, so it has a replication process that it will be eager to begin. Now, the immune systems first line of defense (after the skin) is the <mark>macrophages</mark> (white blood cell which specializes in engulfing and destroying foreign invaders), so they attempt to shut down the virus before it gets any worse, however they do not succeed. The interaction between the virus and the macrophages end up causing inflammation within the body they reside in, this is caused by the macrophages beginning to attack themselves. This distraction allows the virus to multiply. (Everything after this point is pretty much fictional).</div>]]></description>
         <enclosure url="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564112/" />
         <pubDate>2019-03-03 21:33:30 UTC</pubDate>
         <guid>https://padlet.com/coulterek/dgdycnbzjnm6/wish/337279203</guid>
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      <item>
         <title>Step THREE: After Surpassing the Macrophages</title>
         <author>coulterek</author>
         <link>https://padlet.com/coulterek/dgdycnbzjnm6/wish/337279351</link>
         <description><![CDATA[<div>After the macrophages had been so heavily distracted the next step is to include the <mark>helper t-cells</mark> (white blood cells that specialize in identifying the intruder by recognizing their antigen). The helper t-cells identify the virus and call for the proper reinforcements; B-Cells</div>]]></description>
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         <pubDate>2019-03-03 21:35:04 UTC</pubDate>
         <guid>https://padlet.com/coulterek/dgdycnbzjnm6/wish/337279351</guid>
      </item>
      <item>
         <title>About Chikungunya (pathogen)</title>
         <author>coulterek</author>
         <link>https://padlet.com/coulterek/dgdycnbzjnm6/wish/337279382</link>
         <description><![CDATA[<div><strong><mark>What Is It?:</mark></strong> An infectious disease/virus (pathogen).<br><strong><mark>Cause:</mark></strong> Mosquito Bites<br><strong><mark>Symptoms: </mark></strong>Fever, join pain, headache, muscle  pain, joint swelling, and rash formation. In more serious cases it can be disabling, and even cause death.<br><strong><mark>Risk of death:</mark></strong> 1 in 1000<br><strong><mark>Those at most risk:</mark></strong> Children, elderly, and people with a bad medical history.<br><strong><mark>Incubation Period:</mark></strong> Can show up any time between 2 to 12 days. <br><strong><mark>Where In The World:</mark></strong><strong> </strong>Outbreaks occur in Africa, Asian, Europe, and the Indian and Pacific Oceans.<strong><br></strong><strong><mark>Prevention:</mark></strong> There is no vaccine so the only way to avoid it is to avoid mosquito bites.</div>]]></description>
         <enclosure url="" />
         <pubDate>2019-03-03 21:35:22 UTC</pubDate>
         <guid>https://padlet.com/coulterek/dgdycnbzjnm6/wish/337279382</guid>
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      <item>
         <title>Step FOUR: Failure of Antibody attempt</title>
         <author>coulterek</author>
         <link>https://padlet.com/coulterek/dgdycnbzjnm6/wish/337285673</link>
         <description><![CDATA[<div>After the<mark> B-cells</mark> are called they immediately start making antibodies to match the invader's <mark>antigen</mark> (kind of acts as an ID for an invader and induces the creation of antibodies). This <mark>antibody </mark>(blood protein produced to contrast an invader antigen) is soon released to bond to the antigen and in turn neutralizes the invader. However, since Chikungunya is a virus this does not work. Since it is replicating so fast and can not be taken down quite as easily due to it taking over existing cells in the body, <mark>Killer T-Cells</mark> (white blood cells specialized to kill host cells of the viruses and attempt to elimate the virus as well) are called. </div>]]></description>
         <enclosure url="" />
         <pubDate>2019-03-03 22:24:04 UTC</pubDate>
         <guid>https://padlet.com/coulterek/dgdycnbzjnm6/wish/337285673</guid>
      </item>
      <item>
         <title>Step FIVE: Killer T-Cells</title>
         <author>coulterek</author>
         <link>https://padlet.com/coulterek/dgdycnbzjnm6/wish/337285704</link>
         <description><![CDATA[<div>After eliminating the host cell, the antibodies that were being released for the viruses antigen can finally grasp the virus and make the virus vulnerable to the macrophages once again. Therefore, making it so the macrophages can successfully engulf the virus.</div>]]></description>
         <enclosure url="https://padlet-uploads.storage.googleapis.com/361527007/e7898c2dc61cf3d21a7543439bdc513c/dust_macrophage.jpg" />
         <pubDate>2019-03-03 22:24:18 UTC</pubDate>
         <guid>https://padlet.com/coulterek/dgdycnbzjnm6/wish/337285704</guid>
      </item>
      <item>
         <title>Step SIX: Suppressing</title>
         <author>coulterek</author>
         <link>https://padlet.com/coulterek/dgdycnbzjnm6/wish/337285726</link>
         <description><![CDATA[<div>After the "violent" part of the process is over with, the <mark>supresser t-cells</mark> appear on site to end the process, signifying that the virus has been defeated.</div>]]></description>
         <enclosure url="" />
         <pubDate>2019-03-03 22:24:26 UTC</pubDate>
         <guid>https://padlet.com/coulterek/dgdycnbzjnm6/wish/337285726</guid>
      </item>
      <item>
         <title>FINAL Step: Lest We Forget</title>
         <author>coulterek</author>
         <link>https://padlet.com/coulterek/dgdycnbzjnm6/wish/337287860</link>
         <description><![CDATA[<div>After the whole process is done and over with, the immune system goes back to normal and every cell takes up their normal line of defense, but the <mark>memory t-cells</mark> stay and remember how to defeat this specific virus.</div>]]></description>
         <enclosure url="" />
         <pubDate>2019-03-03 22:41:10 UTC</pubDate>
         <guid>https://padlet.com/coulterek/dgdycnbzjnm6/wish/337287860</guid>
      </item>
      <item>
         <title>Largest Source</title>
         <author>coulterek</author>
         <link>https://padlet.com/coulterek/dgdycnbzjnm6/wish/337288188</link>
         <description><![CDATA[<div>Magic doctor haha</div>]]></description>
         <enclosure url="https://www.youtube.com/watch?v=LqLuHnCOWTk" />
         <pubDate>2019-03-03 22:44:13 UTC</pubDate>
         <guid>https://padlet.com/coulterek/dgdycnbzjnm6/wish/337288188</guid>
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