A father can never pass on a mitochondrial condition ,because he  does not pass on his mitochondrial genes. If a mother is affected ,regasrdless of whether they are male or female, because she always passes her mitochondrial genes to all her children.

Because mitochondrial diseases (diseases due to malfunction of mitochondria) can be inherited both maternally and through chromosomal inheritance, the way in which they are passed on from generation to generation can vary greatly depending on the disease. Mitochondrial genetic mutations that occur in the nuclear DNA can occur in any of the chromosomes (depending on the species). Mutations inherited through the chromosomes can be autosomal dominant or recessive and can also be sex-linked dominant or recessive.


The number of affected mtDNA molecules inherited by a specific offspring can vary greatly because

The cross between flowers from white, green, and variegated plants showed maternal inheritance, a form of inheritance wherein the traits of the offspring are maternal in origin due to the expression extranuclear DNA present in the ovum during fertilisation. This indicated that the colour of the seed plant determined the colour of the offspring. The seed plants that are white or green will produced only offspring that are white or green, respectively. Furthermore, seed plants that are variegated can produce all three types of offspring in unpredictable ratios.

For instance, a mother with a disease caused by mitochondrial mutation may lack normal mitochondria. Thus, she will pass on mutation-bearing mitochondria to her children.

Maternal inheritance, a type of inheritance in which the features of the offspring are maternal in origin due to the expression of extranuclear DNA present in the ovum during fertilisation, was demonstrated by the cross between flowers from white, green, and variable colour plants. This demonstrated that the coloration was determined by the colour of the seef plant. Only offspring that are white or green, respectively, will be produced by the seed plants. Variegated seed plants can also give rise to all three sorts of progeny in erratic proportions.

This is so that a father cannot pass on mitochondrial diseases or his own mitochondrial DNA to his offspring. However, regardless of the gender of her children, if a mother is affected, she can still carry and pass the mitochondrial DNA to all of them.

    Mitochondria are vital organelles within cells that are responsible for producing energy in the form of adenosine triphosphate (ATP). Mutations or abnormalities in mtDNA can lead to mitochondrial disorders, which are genetic conditions that primarily affect the energy-producing function of cells.
      One example of a mitochondrial disorder is Leigh syndrome, also known as Leigh disease or subacute necrotizing encephalomyelopathy. It is a progressive neurological disorder that primarily affects infants and children. Leigh syndrome is caused by mutations in mitochondrial DNA or nuclear DNA that affect the function of mitochondria.