Genetic Engineering by payton defina

paytondefina — 2024-01-26 20:55:13 UTC

paytondefina — 2024-01-26 20:58:02 UTC

I plan to explore the ethical concerns behind human genome editing and understand the science behind its potential benefits and dangers.

paytondefina — 2024-01-26 21:05:45 UTC

Risks and benefits of human germline genome editing: An ethical analysis- PubMed

paytondefina — 2024-01-26 21:11:27 UTC

One of the biggest concerns is that scientists don't have enough information on the future generations of someone who has a manufactured gene. not to mention, they also do not know much about the risks of the individual as they age.

Human Genome Editing : Science, Ethics, and Governance

paytondefina — 2024-01-26 21:13:00 UTC

“Gene therapy is the introduction of exogenous genes into cells with the goal of ameliorating a disease condition. This is most efficiently done using viral vectors that take advantage of a virus’s natural ability to enter cells.”

The technical risks of human gene editing- PubMed

paytondefina — 2024-01-26 21:25:33 UTC

Scientists have been able to successfully prevent muscular dystrophy by intruding a manufactured nuclease, restoring normal gene expression.

Benefits

paytondefina — 2024-01-26 21:25:49 UTC

Dangers

paytondefina — 2024-01-26 21:54:21 UTC

A potential danger of CRISPR gene editing — and why base editing may be safer- Boston Children's Hospital

paytondefina — 2024-01-26 21:55:03 UTC

"They found that CRISPR increased the chance of large rearrangements of DNA. While this was uncommon — occurring up to 5 to 6 percent of the time in the study’s experimental model — such rearrangements can theoretically trigger cancer."

What are the ethical issues surrounding gene therapy?

paytondefina — 2024-01-26 22:18:31 UTC

How can “good” and “bad” uses of these technologies be distinguished?
Who decides which traits are normal and which constitute a disability or disorder?
Will the high costs of gene therapy make it available only to the wealthy?
Could the widespread use of gene therapy make society less accepting of people who are different?
Should people be allowed to use gene therapy to enhance basic human traits such as height, intelligence, or athletic ability?
Because people who would be affected by germline gene therapy are not yet born, they can’t choose whether to have the treatment.
- Medline Plus

Ethical concerns temper optimism about gene-editing for human diseases

paytondefina — 2024-01-26 22:25:16 UTC

The most dramatic advance has been for sickle cell disease and a related condition known as beta thalassemia. The summit highlighted Victoria Gray, a Mississippi sickle cell patient who NPR has been following for years. Gray and several dozen other patients have essentially been cured. And the treatment she got could be the first gene-editing treatment to get approved this year.