Albinism In Mice by GAEL SARMIENTO https://padlet.com/gasarmiento2/dam706xew523bpob Gael Sarmiento- Effects Of Mutations en-us 2022-03-17 01:37:11 UTC 2022-03-18 03:34:55 UTC hello@padlet.com https://padlet.net/icons/png/1f47e.png DNA & RNA Bases gasarmiento2 https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099120913 2022-03-17 01:49:31 UTC https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099120913 What is a gene? gasarmiento2 https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099126152 -A gene is a basic unit of heredity and a sequence of nucleotides made up from DNA that encodes the synthesis of a gene product]]> 2022-03-17 01:53:03 UTC https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099126152 Which gene is affected? gasarmiento2 https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099144646
-Mice have an enzyme called tyrosinase or TYR for short. The tyrosinase (TYR) is located in the melanocytes.

-The mutated tyrosinase (TYR) gene is responsible for pigment molecules that color the skin, hair, and eyes.]]> 2022-03-17 02:05:23 UTC https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099144646 gasarmiento2 https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099154296 2022-03-17 02:11:57 UTC https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099154296 gasarmiento2 https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099162976 2022-03-17 02:17:29 UTC https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099162976 What mutations occur in albinism mice's? gasarmiento2 https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099176988 -The Mutation that occurs in tyrosinase (TYR) is DELETION meaning a total absence of pigmentation due to a mutation in the tyrosinase gene. Melanocyte (responsible for giving skin, hair and eyes pigmentation) is interfere with their pigment production or their ability to distribute it to the cells in the epidermis, or outer layer of the skin.]]> 2022-03-17 02:26:25 UTC https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099176988 The result affects of the mutation from albinism in mice: gasarmiento2 https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099185382 -OCA1. or TYR results from a genetic defect in an enzyme called tyrosinase. This enzyme helps the body to change the amino acid,tyrosine,into pigment. The result of this physically leaves the mice with snow-white skin, as well as hair, and no pigment in their eyes. This makes their eyes (the iris) a pale bluish pinkish color, while the pupil is red.]]> 2022-03-17 02:32:00 UTC https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099185382 Transcription: gasarmiento2 https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099216959 (Transcription always comes before Translation!)
-Transcription occurs in Cells in the nucleus where DNA is. The DNA is going to be transcribed into a message. In this a enzyme called RNA polymerase will connect complementary RNA bases with the DNA. This in result creates a single stranded mRNA (m=messenger) 
Part Two 
-The mRNA are able to leave the nucleus into the cytoplasm where in the cytoplasm it attaches into a ribosome. Ribosomes make proteins and are made of rRNA(ribosomal RNA)
]]> 2022-03-17 02:53:59 UTC https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099216959 gasarmiento2 https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099218177 2022-03-17 02:54:52 UTC https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099218177 Translation: gasarmiento2 https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099247196 (Translation comes after Transcription)
-In the cytoplasm there are tons of tRNA molecules (transfer RNA), the tRNA carry amino acids. Amino acids are what proteins are made from. The mRNA directs which tRNA come in and which amino acid is transfered, this is why the mRNA is called the messenger. The tRNA are looking for complementary bases and when they do they transfer the
amino acids in threes.
Part Two
-Called the Codon  (Ex: cac uac aac) the tRNA with the required anticodon lets just say for example "UAC" comes to pair with the complementary AUG codon. This transfers the amino acid the tRNA carries, the tRNA will leave while the amino acid attaches to the other tRNA amino acid with the help of peptide bond . Eventually the cycle will continue until the there is a stop codon. This means the protein building is complete. ]]> 2022-03-17 03:15:25 UTC https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099247196 gasarmiento2 https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099249471 2022-03-17 03:17:04 UTC https://padlet.com/gasarmiento2/dam706xew523bpob/wish/2099249471