Elexacaftor by Julia Pickard https://padlet.com/juliaslp/d7cv8tzjk94n My selected medication en-us 2020-03-27 13:53:26 UTC 2025-09-30 12:02:02 UTC hello@padlet.com Elexacaftor juliaslp https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478426000 Most commonly combined with tezacaftor and ivacaftor to create the combination drug Tricafta]]> 2020-03-27 13:56:48 UTC https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478426000 Class juliaslp https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478429424 Cystic fibrosis transmembrane conductance regulator (CFTR) corrector]]> 2020-03-27 13:58:27 UTC https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478429424 Uses juliaslp https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478435895 Only used in the treatment of cystic fibrosis (CF) patients 12 years of age or older who have at least one F508del mutation in the CTFR gene]]> 2020-03-27 14:01:25 UTC https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478435895 Common side effects juliaslp https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478438363 Body aches, chills, cough, diarrhea, fever, headache, sneezing, sore-throat, tiredness, ear congestion, rash/itchiness.]]> 2020-03-27 14:02:37 UTC https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478438363 Rare and emergent side effects juliaslp https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478442094 Bladder pain, bloody or cloudy urine, blurred vision, coma, painful urination, nightmares, shakiness, slurred speech.

]]> 2020-03-27 14:04:20 UTC https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478442094 Mechanism of action juliaslp https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478444726  increases the amount of mature CFTR proteins present on the surface of cells, resulting in improved ion transport. Helps to improve lung function, nutritional status, and overall quality of life.]]> 2020-03-27 14:05:33 UTC https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478444726 Safe dose range juliaslp https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478448863 Elexacaftor is dosed by 200 mg/dose BID only in patients > 12 years of age.


]]> 2020-03-27 14:07:24 UTC https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478448863 Nursing implications juliaslp https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478453072 Assess kidney function labs, collect urine samples if patient experiences urinary symptoms, educate the patient on importance of hydration and UTI prevention. Educate patient to avoid grapefruit juice and to not drive or operate machinery until they know how the drug affects them. Monitor liver enzymes.

]]> 2020-03-27 14:09:16 UTC https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478453072 juliaslp https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478473190 2020-03-27 14:17:59 UTC https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478473190 juliaslp https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478475531 2020-03-27 14:19:05 UTC https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478475531 juliaslp https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478481189 2020-03-27 14:21:37 UTC https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478481189 juliaslp https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478484171 2020-03-27 14:22:51 UTC https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478484171 juliaslp https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478486894 2020-03-27 14:24:06 UTC https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478486894 juliaslp https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478489738 2020-03-27 14:25:20 UTC https://padlet.com/juliaslp/d7cv8tzjk94n/wish/478489738