Overview of Tetanus by https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua 2020FL-BIOL-2420-20403: Microbiology Non-Sci Majors en-us 2020-12-03 15:34:28 UTC 2025-07-01 01:24:44 UTC hello@padlet.com What is Tetanus? jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984164793 Is it a disease? A virus?
Most people have heard of tetanus but don't know what it actually is. The CDC states that "Tetanus is an infection caused by a bacterium called Clostridium tetani.". Clostridium tetani exists in the environment as spores.

]]> 2020-12-03 15:36:17 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984164793 Disease transmission jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984387003 The CDC notes that tetanus "...bacteria are usually found in soil, dust, and manure and enter the body through breaks in the skin"]]> 2020-12-03 16:18:55 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984387003 Signs and symptoms jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984388682
  • Jaw cramping
  • muscle spasms
  • painful muscle stiffness
  • trouble swallowing
  • seizures
  • headache
  • fever
  • changes in blood pressure
    • ]]>     2020-12-03 16:19:15 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984388682     Virulence factor jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984389904 We've already discussed one of the virulence factors: Tetanospasmin; One other is "Tetanolysin" which causes "a local necrotizing effect" allowing for increased spread.]]> 2020-12-03 16:19:30 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984389904 Being diagnosed jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984391630 Tetanus is usually diagnosed through "...physical exam, medical and immunization history" as opposed to laboratory tests.]]> 2020-12-03 16:19:50 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984391630 Treatments jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984392962 Treatments for lockjaw include:
    • antibiotics to kill the bacteria
    • muscle relaxers
    • a tetanus vaccine
    • wound care
    ]]>     2020-12-03 16:20:05 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984392962     Long term effects (Sequelae) jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984394395
  • "Studies have linked neonatal tetanus to neurological disabilities"
  • One study compared 40 patients to 40 controls and found "significantly more muscle fatigue and cramps, nervousness, decreased mental capacity and difficulties in balance, speech and memory" in the patients.
    • ]]>     2020-12-03 16:20:22 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984394395     Prevention jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984395968 Tetanus can be prevented. The WHO states that "Tetanus can be prevented through immunization with tetanus-toxoid-containing vaccines (TTCV)"]]> 2020-12-03 16:20:39 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984395968 Epidemiology and statistics jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984397623 I'm interactive!

    ]]>     2020-12-03 16:20:55 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984397623     Did you know?💭 #1 jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984398651 Tetanus is also known as lockjaw]]> 2020-12-03 16:21:08 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984398651 Explanations from the creator jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984401347 Video link : Click pop out ]]> 2020-12-03 16:21:39 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984401347 Research citations and links jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984403818 2020-12-03 16:22:08 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984403818 Clostridium tetani jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984538413 2020-12-03 16:47:47 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984538413 3D Interactive model jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984554457 Click me!]]> 2020-12-03 16:50:48 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984554457 What does Tetanus actually do to the body? jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984610545 Once Clostridium tetani has actually gotten a foothold in the body it produces a toxin called " tetanospasmin" that interferes with the communication between your nervous system and your muscles.]]> 2020-12-03 17:01:43 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984610545 Tetanospasmin jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984642256 2020-12-03 17:07:22 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984642256 3D interactive model jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984665147 2020-12-03 17:11:52 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984665147 What is Tetanospasmin? jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984678955 Tetanospasmin is a nerve toxin that "...impairs the nerves that control your muscles (motor neurons)." More specifically it "interfer[es] with the release of neurotransmitters (glycine and γ-aminobutyric acid)".

    ]]>     2020-12-03 17:14:33 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984678955     Want to know even more? jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984731020 2020-12-03 17:24:51 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984731020 About Clostridium tetani jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984751875
  • Gram positive
  • Obligate anaerobe
  • Saprophytic
  • Spore-former
  • Extremely environmentally resilient
    • ]]>     2020-12-03 17:29:02 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/984751875     Did you know?💭 #2 jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/985375173 There are "...at least 209 species" of clostridium]]> 2020-12-03 19:33:59 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/985375173 Did you know?💭 #3 jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/985466830 This kind of model is known as a 

    "Ribbon Diagram"

    ]]>     2020-12-03 19:54:56 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/985466830     Did you know? 💭# 4 jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/985488913 Rust and tetanus are often associated because items left to nature tend to rust and accumulate Clostridium tetani bacteria]]> 2020-12-03 20:00:34 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/985488913 Have a question? jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/985527282 Email: jacob.vondrasek@my.tccd.edu]]> 2020-12-03 20:10:07 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/985527282 Tetanus toxoid vaccines jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/985778313 The Tetanus vaccine is a toxoid vaccine, a vaccine that uses a toxin produced by the bacteria. This makes a person immune to the toxin as opposed to the bacteria. For the pharmacology information go here:]]> 2020-12-03 21:27:20 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/985778313 Vaccines in use jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/985814202 4 available: 
    • DT (diphtheria and tetanus) used for <7yrs
    • DTaP(diphtheria, tetanus, and pertussis) used for <7yrs
    • TD (tetanus and diphtheria)
    • Tdap (Tetanus, diphtheria, and pertussis)

    ]]>     2020-12-03 21:40:43 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/985814202     More visual look at transmission jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/985853937 Made by a bad artist(me)]]> 2020-12-03 21:54:55 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/985853937 Did you know?💭 #5 jacobvondrasek https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/988567999 Anti-vaccination is a factor in the spread of diseases!
    More info here:]]>     2020-12-04 17:58:26 UTC https://padlet.com/jacobvondrasek/d4cq6hwzaie07zua/wish/988567999