Unit 2 assignment by Vivian Sanchez https://padlet.com/viviansanchez/cyob4zg7iq54xfip Pharmacology ANS en-us 2020-10-13 02:03:36 UTC 2020-10-15 06:25:30 UTC hello@padlet.com https://padlet.net/icons/png/1f913.png Divisions of the Autonomic Nervous System (aka Visceral Division) viviansanchez https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823401446 ~Parasympathetic division
AKA craniosacral
rest and digest

~Sympathetic division
AKA thoracolumbar division
fight or flight]]> 2020-10-13 02:12:39 UTC https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823401446 Parasympathetic Division Neurotransmitter: viviansanchez https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823458018 Acetylcholine (ACH)

Released from: ACH from ganglia and post-ganglionic nerve ending]]> 2020-10-13 02:42:54 UTC https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823458018 Sympathetic Division Neurotransmitters: viviansanchez https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823463798 Acetylcholine (ACH)
Norepinephrine (NE)

Released from: Adrenal medulla releases EPI from ganglia and NE from post-ganglionic nerve]]> 2020-10-13 02:46:18 UTC https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823463798 Receptors of each division: viviansanchez https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823570698 Parasympathetic-
cholinergic (muscarinic & nicotinic) receptors
located on cardiac, smooth muscle and glands

Sympathetic-
adrenergic (alpha & beta) receptors
located on the arteries]]> 2020-10-13 03:55:51 UTC https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823570698 Parasympathetic Organ and Stimulus response: viviansanchez https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823571465 Pupil - constriction
Heart - slight drop in contractility, decrease in heart rate, AV conduction slows
Respiratory passages - bronchoconstriction
Intestines/GI tract - increased digestion/motility
Urinary bladder - contracts
Urinary sphincter - relaxes]]> 2020-10-13 03:56:24 UTC https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823571465 Drug classification for Sympathetic division: viviansanchez https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823579956 Sympathomemetics (alpha & beta agonists)
Alpha drugs > a1 receptor > vasocontriction
                         a2 receptor > decrease release of NE

Nonselective beta drugs > b1 > increase heart rate/contraction
                                                b2 > bronchodilation of lungs
Selective beta drugs > b2 > bronchodilation of lungs

Sympatholytics (alpha, beta, & neuronal antagonists)
Selective alpha-1 blockers > a1 > vasodilation
Nonselective beta blockers > b1 > decrease heart rate/contraction
                                                    b2 >  smooth muscle contraction 
Selective beta-1 blockers > b1 > decrease heart rate and contraction
Neuronal blockers > adrenergic nerve ending > interrupts formation/release of NE, drops BP, decreases cardiac function

]]> 2020-10-13 04:02:04 UTC https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823579956 Specific Drug Examples: viviansanchez https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823581656 Alpha drugs:
-  phenylephrine (Neo-Synephrine®) 
-  ephedrine

Nonselective beta drugs:
- nadolol (Corgard®)
- propanolol (Inderol®)

Selective beta drugs: 
- atenolol (Tenormin®)
-  metoprolol (Lopressor®)

Selective alpha-1 blockers:
- doxazosin (Cardura®)
-  terazosin (Hytrin®) 

Direct acting cholinergic agonists:
- pilocarpine (Pilocarterazosin®) 
- bethanecol (Urencholineterazosin®)

Indirect acting cholinergic agents:
- neostigmine (Prostigmin®)

Anticholinergic:
- dicyclomine (Bentyl®)]]> 2020-10-13 04:03:04 UTC https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823581656 Alternate terms: viviansanchez https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823583660 Agonist: adrenergics, agonists

Antagonist: adrenergic blocking, inhibitors]]> 2020-10-13 04:04:18 UTC https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823583660 Sympathetic Organ and Stimulus response: viviansanchez https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823587346
Adrenal medulla - release of epinephrine
Pupil - dilation
Heart - increase in heart rate and conduction
Arteries - vasoconstriction
Lungs - bronchodilation
Intestines/GI tract - decreased motility/excretion
Urinary bladder - relaxes
Urinary sphincter - contracts]]> 2020-10-13 04:06:44 UTC https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823587346 Sources: viviansanchez https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823598388 Unit 2 Lecture notes part 1
Unit 2 Lecture notes part 2
Hitner, Henry, and Barbara Nagle. Pharmacology for Health Professions. McGraw-Hill, 2012. ]]> 2020-10-13 04:13:51 UTC https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/823598388 Drug classification for Parasympathetic division: viviansanchez https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/830476099 Parasympathomimetics:
Direct acting cholinergic drugs > muscarinic receptor > decrease in heart rate (negative feedback), bronchoconstriction

Indirect acting cholinergic drugs > muscarinic receptors > contraction of smooth muscles, bronchoconstriction, vasodilation, increase in bodily secrection, decrease in heart rate

Anticholinergic drugs > nocotinic receptors > increased heart rate and contractility, pupil dilation, decrease in sweat gland secretions, ]]> 2020-10-14 23:13:34 UTC https://padlet.com/viviansanchez/cyob4zg7iq54xfip/wish/830476099