https://padlet.com/as14317/ctopws15zlk24m9t en-us 2022-05-17 13:31:51 UTC 2025-05-20 03:10:15 UTC hello@padlet.com as14317 https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187621510 2022-05-17 13:32:24 UTC https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187621510 as14317 https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187621838 AKA 1st Generation
Examples: Haloperidol, Chlorpromazine, Zuclopenthixol Deconate (Clopixol)
MOA: Dopamine Receptor Antagonists]]> 2022-05-17 13:32:36 UTC https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187621838 as14317 https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187622267 AKA 2nd Generation

Examples: Olanzapine, Aripiprazole, Risperidone, Quetiapine, Clozapine
MOA: Dopamine and serotonin receptor antagonists
(and many other receptors)

]]> 2022-05-17 13:32:49 UTC https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187622267 as14317 https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187626510 A 21-year old university student has been admitted onto the psychiatric ward following a suicide attempt. He reports a 6 month history of beliefs about his flatmates being spies trying to poison him, and says that he had begun hearing voices that were encouraging him to end his life to escape them. A diagnosis of schizophrenia was reached, what would be the best pharmacological treatment to commence him on?

Explain your reasoning in the Teams chat]]> 2022-05-17 13:35:09 UTC https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187626510 12lworthington https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187645906 EXTRA-PYRAMIDAL = ADAPT
Acute Dystonia
Akathisia
Parkinsonism
Tardive dyskinesia]]> 2022-05-17 13:46:09 UTC https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187645906 as14317 https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187655497 2022-05-17 13:51:07 UTC https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187655497 as14317 https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187662253 METABOLIC
Weight gain
Diabetes
Raised cholesterol

Others:
Q for Quetiapine, Q for QT interval prolongation
Risperidone causes extra-pyramidal side effects

]]> 2022-05-17 13:54:38 UTC https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187662253 12lworthington https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187664714

Abnormal Tone

Torticollis = Twisting of the neck

Oculogyric Crises = Upward Deviation of eyes

Treatment = Pro-Cyclidine (Anti-Cholinergic)

]]> 2022-05-17 13:55:57 UTC https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187664714 mollyannerichards https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187665413 Efficacy? 
Side-effects?]]> 2022-05-17 13:56:17 UTC https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187665413 12lworthington https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187674910

Restless

Pacing

(Un)Crossing Legs

Treatment = Change Drug/ Propranolol

]]> 2022-05-17 14:00:59 UTC https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187674910 12lworthington https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187678197

Tremor

Rigidity

Bradykinesia

Treatment = Change Drug/ Pro-Cyclidine (Anti-Cholinergic)

]]> 2022-05-17 14:02:36 UTC https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187678197 as14317 https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187684573 Very effective but very problematic

Common side-effects: constipation, hypersalivation, weight gain

Emergency side-effects: agranulocytosis, myocarditis 

Requires regular monitoring]]> 2022-05-17 14:05:52 UTC https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187684573 mollyannerichards https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187690835 Let us know in the comments below if what you would first prescribe a patient newly diagnosed with schizophrenia.

How would you try to improve compliance in patients reluctant to take their antipsychotic medications? ]]> 2022-05-17 14:08:45 UTC https://padlet.com/as14317/ctopws15zlk24m9t/wish/2187690835 12lworthington https://padlet.com/as14317/ctopws15zlk24m9t/wish/2189801501

Rhythmic Movements

Grimace & Chewing

Lip smacking

Treatment = Tetrabenzine

]]> 2022-05-18 16:24:02 UTC https://padlet.com/as14317/ctopws15zlk24m9t/wish/2189801501 as14317 https://padlet.com/as14317/ctopws15zlk24m9t/wish/2190156317 Dopamine inhibits pituitary prolactin synthesis
Dopamine antagonists increase prolactin

Symptoms: amenorrhoea, galactorrhoea, low libido

*Aripiprazole reduces prolactin production*]]> 2022-05-18 20:45:43 UTC https://padlet.com/as14317/ctopws15zlk24m9t/wish/2190156317 as14317 https://padlet.com/as14317/ctopws15zlk24m9t/wish/2190181781 2022-05-18 21:14:27 UTC https://padlet.com/as14317/ctopws15zlk24m9t/wish/2190181781