https://padlet.com/kelabb189/crsrw0q85i6h Made with swagger en-us 2019-03-08 15:02:27 UTC 2023-02-18 18:57:16 UTC hello@padlet.com kelabb189 https://padlet.com/kelabb189/crsrw0q85i6h/wish/339329269 Brain sends a AP through the motor unit down the neuromuscular junction, a nerve impulse opens the voltage gated calcium ion channels which increases the release of Ach, Ach binds to receptor sights which activates voltage gated sodium channels, more Na+ is pumped into the cell making it depolarized, depolarization will spread to adjacent areas opening sodium channels and eventually initiating AP that moves along the lengths of the sarcolemma, Na+ stimulates a change in membrane permeability by opening K+ pumps which allow the K+ to diffuse across the sarcolemma and out of the muscle fiber ]]> 2019-03-08 15:05:37 UTC https://padlet.com/kelabb189/crsrw0q85i6h/wish/339329269 kelabb189 https://padlet.com/kelabb189/crsrw0q85i6h/wish/339329368 Step 1:  Action Potential moves down the sarcolemma and down the T-tubules  

 

]]> 2019-03-08 15:05:47 UTC https://padlet.com/kelabb189/crsrw0q85i6h/wish/339329368 kelabb189 https://padlet.com/kelabb189/crsrw0q85i6h/wish/339329420 Step 2: Transmission of the AP along the T-tubules cause the adjacent sarcoplasmic reticulum to release Ca2+ which flows into the cytosol ]]> 2019-03-08 15:05:52 UTC https://padlet.com/kelabb189/crsrw0q85i6h/wish/339329420 kelabb189 https://padlet.com/kelabb189/crsrw0q85i6h/wish/339329595 Step 3 and 4: Ca2+ combines with troponin and removes the blocking actin of tropomyosin by changing the shape of actin so that the myosin binding sites are exposed and than the myosin binds to the actin forming cross bridges and contraction begins

]]> 2019-03-08 15:06:10 UTC https://padlet.com/kelabb189/crsrw0q85i6h/wish/339329595 kelabb189 https://padlet.com/kelabb189/crsrw0q85i6h/wish/339329730 step 1: Cross bridge formation, energized myosin head attaches to an actin myosin filament, forming a cross bridge

]]> 2019-03-08 15:06:23 UTC https://padlet.com/kelabb189/crsrw0q85i6h/wish/339329730 kelabb189 https://padlet.com/kelabb189/crsrw0q85i6h/wish/339329840 step 2: The power stroke. ADP and p are released and the myosin head pivots and bends, changing to its bent low energy state. As a result it pulls the actin filament toward the M line ]]> 2019-03-08 15:06:30 UTC https://padlet.com/kelabb189/crsrw0q85i6h/wish/339329840 kelabb189 https://padlet.com/kelabb189/crsrw0q85i6h/wish/339329919 Step 3: Cross bridge detachment. After ATP attaches to myosin, the link between myosin and actin weakens and the myosin head detaches ]]> 2019-03-08 15:06:39 UTC https://padlet.com/kelabb189/crsrw0q85i6h/wish/339329919 kelabb189 https://padlet.com/kelabb189/crsrw0q85i6h/wish/339329987 Step 4: Cocking of the myosin head. As ATP is hydrolyzed to ADP and p, the myosin head returns to its prestrike high-energy or "cocked" postion]]> 2019-03-08 15:06:45 UTC https://padlet.com/kelabb189/crsrw0q85i6h/wish/339329987