The history and process of Malaria by Antoinette (Netty) Andrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh en-us 2023-01-10 01:58:50 UTC 2023-01-17 02:08:21 UTC hello@padlet.com Poverty: People do not have resources to protect themselves from Miquitos, and do not have entertainment inside their homes so they go outside and get exposed to Malaria carrying Mosquitos antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2438650846 2023-01-10 02:02:31 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2438650846 Misqito bites someone carrying the single cell parisite Plasmodium, it multiplies and migrates to the mosquitos salivary glands antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2438652437 2023-01-10 02:04:51 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2438652437 In the 1600's the bark of the cinchona tree is found= becomes effective cure antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2438657224 2023-01-10 02:11:24 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2438657224 Originally people believe Malaria was caused by bad air and myzama's, but in 1897 Ronald Ross discovers that mosquitos are the source of the spread antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2438658003 2023-01-10 02:12:32 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2438658003 The parasite evolves 7 times, each time becoming immune and unrecognizable to previous malaria treatments antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2438659535 2023-01-10 02:14:15 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2438659535 Parasite is able to hide in the body for long periods of time antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2438659763 2023-01-10 02:14:34 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2438659763 symptoms: Fever, headaches, chills: noticed after 10-15 days. The time between being infected with Malaria and the time you show symptoms is referred to as the incubation period. antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2438660665 2023-01-10 02:15:54 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2438660665 Quinin kills the parasite and prevents it from growing antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2439761840 2023-01-10 18:06:45 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2439761840 Chloroquine phosphate was the perfered treatment until many parasites across the world became immune to it's effect antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2439765604 2023-01-10 18:09:16 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2439765604 If Chloroquine phosphate does not work, Artemisinin-based combination therapies (ACTs) is the next best option. It combines 2 or more drugs to act against the parasite antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2439767180 2023-01-10 18:10:21 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2439767180 The two ways to treat malaria would be antiparaisitc and antibiotics. Antiparasitic kills the parasite, and some even help to prevent the parasite from reemerging. Antibiotics, stop the growth and spread of the parasite, but it would still be in the system. antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2439777619 2023-01-10 18:17:01 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2439777619 antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2439778913 2023-01-10 18:17:57 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2439778913 antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2439781504 2023-01-10 18:19:38 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2439781504 A bite from an infected female Anopheles mosquito, also known as the vector, injects sporozoites into the human body. antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2439789147 2023-01-10 18:24:53 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2439789147 They do asexual replication of their haploid genome. Within RBCs parasites develop through ring, trophozoite, and schizont stages. antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2443000612 2023-01-13 00:58:25 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2443000612 Inside a hepatocyte, schizogony occurs where a parasite divides into merozoites. Merozoites enter the bloodstream and invade erythrocytes, causing a new wave of schizogony within red blood cells. antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2443005188 2023-01-13 01:05:52 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2443005188 Protozoa are a group of single-celled eukaryotes, either free-living or parasitic, that feed on organic matter such as other microorganisms or organic tissues and debris. antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2443015120 2023-01-13 01:19:34 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2443015120 Hemoglobin in blood carries oxygen from the respiratory organs to the rest of the body. Malaria greatly decreases hemogoblin consentration. antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2443022151 2023-01-13 01:27:55 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2443022151 The resulting mature schizont is segmented in appearance and contains 16–32 daughter merozoites. The infected RBC (iRBC) ruptures, releasing the daughter sporozoites to invade new RBCs. antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2444005915 2023-01-13 19:45:55 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2444005915 antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2446040518 2023-01-16 20:42:37 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2446040518 antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2446045046 2023-01-16 20:49:58 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2446045046 can lead to seizures, brain damage, trouble breathing, and organ failure. antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2446047502 2023-01-16 20:54:34 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2446047502 antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2446050330 2023-01-16 20:59:07 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2446050330 The sporozoites travel through blood vessels and cells to the liver in order to infect hepatocytes and replicate inside the cell. antoinetteandrews https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2446220082 2023-01-17 02:07:59 UTC https://padlet.com/antoinetteandrews/cahpsquvnc7qu3zh/wish/2446220082