Feedback on the use of CRISPR functional genomic tool for drug discovery by Yap Wei Hsum . https://padlet.com/weihsumyap1/c4rn5cxt64jh State one point in which you find most relevant/related to the Topic (Target discovery and validation) en-us 2017-09-12 11:15:44 UTC 2018-09-16 05:32:00 UTC hello@padlet.com Wai Leong :) leewl0108 https://padlet.com/weihsumyap1/c4rn5cxt64jh/wish/278514077 -        Ability of CRISPR–Cas to help identify target molecules.
-        By using the system to deliberately activate or inhibit genes, researchers can determine the genes and proteins that cause or prevent disease, therefore identifying targets for potential drugs.
]]> 2018-09-06 16:07:15 UTC https://padlet.com/weihsumyap1/c4rn5cxt64jh/wish/278514077 Chan Le Roy https://padlet.com/weihsumyap1/c4rn5cxt64jh/wish/280610948 - The possibility of improving CRISPR-CAS technology that will help treat genetic diseases in the future and therefore, improving the lives of people. Since it uses a combination of a synthetic guide RNA molecule and an enzyme (typically Cas9) from the bacterial immune system to edit DNA with unprecedented ease and precision. Furthermore, it enables scientists to more accurately verify the safety and efficacy of drugs, which ensures that such models are better predictors of what will happen in clinical trials. ]]> 2018-09-13 00:17:25 UTC https://padlet.com/weihsumyap1/c4rn5cxt64jh/wish/280610948 Chong Jia En https://padlet.com/weihsumyap1/c4rn5cxt64jh/wish/280612095 CRISPR-Cas9 enables us to identify targets by inhibiting or activating genes to determine the proteins and genes that prevent or cause a disease. It also makes it easier for researchers to create cellular and whole animal models that mimics the action of the disease. These properties allows the more accurately verify the safety and efficacy of the drug, making the models a better predictor of the action of the drug during clinical trials. ]]> 2018-09-13 00:24:16 UTC https://padlet.com/weihsumyap1/c4rn5cxt64jh/wish/280612095