Prepare Your Plan by Micalea Goldenberg https://padlet.com/mgoldenberg4/btdwndi1nzrdppkf 2.2.6 PLTW PBS en-us 2022-06-02 17:47:56 UTC 2026-03-01 17:14:26 UTC hello@padlet.com Kim Family Gel Electrophoresis mgoldenberg4 https://padlet.com/mgoldenberg4/btdwndi1nzrdppkf/wish/2209276134 2022-06-02 17:51:14 UTC https://padlet.com/mgoldenberg4/btdwndi1nzrdppkf/wish/2209276134 Provide the Family With... mgoldenberg4 https://padlet.com/mgoldenberg4/btdwndi1nzrdppkf/wish/2209278242 Information About the Condition
A Summary of the Results of Lab Tests
Pedigree and Punnett Square Analysis
Prognosis and Treatment]]> 2022-06-02 17:53:18 UTC https://padlet.com/mgoldenberg4/btdwndi1nzrdppkf/wish/2209278242 Information About the Condition mgoldenberg4 https://padlet.com/mgoldenberg4/btdwndi1nzrdppkf/wish/2209279732 Research familial hypercholesterolemia and note the pattern of inheritance as well as which chromosome is impacted.

]]> 2022-06-02 17:54:51 UTC https://padlet.com/mgoldenberg4/btdwndi1nzrdppkf/wish/2209279732 Information About the Condition mgoldenberg4 https://padlet.com/mgoldenberg4/btdwndi1nzrdppkf/wish/2209279868 Write a paragraph or two that explains to Aki, in simple terms, what FH is and how it might affect members of his family who have the LDLR gene mutation that causes FH. Include average cholesterol levels for individuals with the mutated LDLR gene and discuss the dangers of high cholesterol.
Reminder: You learned about the relationship between cholesterol levels and heart disease in Activity 2.1.4. Refer to this information and complete additional research as needed. ]]> 2022-06-02 17:55:00 UTC https://padlet.com/mgoldenberg4/btdwndi1nzrdppkf/wish/2209279868 A Summary of the Results of Your Laboratory Testing mgoldenberg4 https://padlet.com/mgoldenberg4/btdwndi1nzrdppkf/wish/2209281413 Sketch your finished gel with the stained DNA fragments. Clearly label each lane.

To determine the genotype of each patient, analyze the pattern of restriction fragments from the five patients, as follows: 
  • homozygous normal for the LDL receptor (ff)
  • homozygous for the defective LDL receptor (FF)
  • heterozygous for the defective LDL receptor (Ff)
]]> 2022-06-02 17:56:38 UTC https://padlet.com/mgoldenberg4/btdwndi1nzrdppkf/wish/2209281413 Pedigree and Punnett Square Analysis mgoldenberg4 https://padlet.com/mgoldenberg4/btdwndi1nzrdppkf/wish/2209282121 Note: If needed, refer to what you learned in the Pedigree and Punnett Square Practice resource to organize your pedigree and add proper shading. 
  • Deduce the genotype of members of the Kim family who were not tested.
  • Draw a pedigree for familial hypercholesteremia in Aki’s family. Provide a key for the pedigree.
]]> 2022-06-02 17:57:23 UTC https://padlet.com/mgoldenberg4/btdwndi1nzrdppkf/wish/2209282121 Prognosis and Treatment mgoldenberg4 https://padlet.com/mgoldenberg4/btdwndi1nzrdppkf/wish/2209282679
  • Write a brief statement identifying which of the family members are most at risk for having high cholesterol.
  • Describe treatment options for family members with FH. Be sure to include the class of medications called statins.
    • ]]>     2022-06-02 17:57:56 UTC https://padlet.com/mgoldenberg4/btdwndi1nzrdppkf/wish/2209282679     Gel Electro mgoldenberg4 https://padlet.com/mgoldenberg4/btdwndi1nzrdppkf/wish/2209285637 Lane 1: Standard DNA Marker
    Lane 2: Normal DNA Sample (ff)
    Lane 3: FH Control (FF)
    Lane 4: Changman, Aki's father
    Lane 5: Jia, Aki's Sister
    Lane 6: Aki
    Lane 7: Justin, Aki's Brother-in-Law
    Lane 8: Amy, Aki's niece]]>     2022-06-02 18:00:48 UTC https://padlet.com/mgoldenberg4/btdwndi1nzrdppkf/wish/2209285637     Gel Electrophoresis mgoldenberg4 https://padlet.com/mgoldenberg4/btdwndi1nzrdppkf/wish/2209288945 Identify the Genotype and Phenotype of...
    - Changman
    - Jia
    - Aki
    - Justin
    - Amy]]>     2022-06-02 18:04:21 UTC https://padlet.com/mgoldenberg4/btdwndi1nzrdppkf/wish/2209288945