Progeria by Armando https://padlet.com/zurca/bs96h3jizs17 project on progeria en-us 2017-05-24 20:20:35 UTC 2023-03-24 04:39:17 UTC hello@padlet.com Introduction zurca https://padlet.com/zurca/bs96h3jizs17/wish/173713777 By: Armando Cruz, and Sebastian  ]]> 2017-05-24 20:25:41 UTC https://padlet.com/zurca/bs96h3jizs17/wish/173713777 Common information zurca https://padlet.com/zurca/bs96h3jizs17/wish/173713987 •The name of the disorder is progeria also called the Hurchinson Gilford Progeria syndrome (HGPS). This disorder is found in children and newborns. Progeria is an extremely rare disorder and occurs in one in every 8 million babies born worldwide.]]> 2017-05-24 20:27:05 UTC https://padlet.com/zurca/bs96h3jizs17/wish/173713987 Symptoms zurca https://padlet.com/zurca/bs96h3jizs17/wish/173714073 •Some signs and symptoms of progeria are hair loss, wrinkles, slow growth, delayed tooth development, high pitched voice, enlarged head, and visible veins. Progeria affects the musculoskeletal system, cardiovascular system, and the skin. The nucleus of the cell is affected by progeria by making an abnormal Lamin A protein called progeria. ]]> 2017-05-24 20:27:52 UTC https://padlet.com/zurca/bs96h3jizs17/wish/173714073 zurca https://padlet.com/zurca/bs96h3jizs17/wish/173714304 2017-05-24 20:29:49 UTC https://padlet.com/zurca/bs96h3jizs17/wish/173714304 zurca https://padlet.com/zurca/bs96h3jizs17/wish/173714557 2017-05-24 20:32:07 UTC https://padlet.com/zurca/bs96h3jizs17/wish/173714557 How its Diagnosed zurca https://padlet.com/zurca/bs96h3jizs17/wish/173714714 •Progeria is diagnosed with a genetic test made specifically for it. Progeria can also be diagnosed by observing the physical symptoms or signs like an enlarged head, visible veins, wrinkles, or dryness, hair loss, and slow growth. The expected life span of someone with progeria (HGPS) is 13 years old.]]> 2017-05-24 20:33:33 UTC https://padlet.com/zurca/bs96h3jizs17/wish/173714714 zurca https://padlet.com/zurca/bs96h3jizs17/wish/173714757 2017-05-24 20:34:04 UTC https://padlet.com/zurca/bs96h3jizs17/wish/173714757 History zurca https://padlet.com/zurca/bs96h3jizs17/wish/173714900 •Progeria comes from the greek word progerus which signifies prematurely old. Progeria is currently diagnosed with genetic testing but used to be diagnosed only by physical signs and observations. Progeria was discovered in 1886 by two doctors by the name of Hasting Gilford and Jonathan Hutchinson. ]]> 2017-05-24 20:35:18 UTC https://padlet.com/zurca/bs96h3jizs17/wish/173714900 zurca https://padlet.com/zurca/bs96h3jizs17/wish/173714967 2017-05-24 20:35:48 UTC https://padlet.com/zurca/bs96h3jizs17/wish/173714967 What causes the disease zurca https://padlet.com/zurca/bs96h3jizs17/wish/173715044 •Progeria is caused by a point mutation in position 1824 of a gene known as the LMNA gene. The gene is responsible for making a protein to help support the cell. Progeria is not sex linked and can happen in families with no link to the disorder at all.]]> 2017-05-24 20:36:34 UTC https://padlet.com/zurca/bs96h3jizs17/wish/173715044 zurca https://padlet.com/zurca/bs96h3jizs17/wish/173715106 2017-05-24 20:37:02 UTC https://padlet.com/zurca/bs96h3jizs17/wish/173715106 Genetic specifics zurca https://padlet.com/zurca/bs96h3jizs17/wish/173715144 •Progeria is not due to any heredity of any sort and is not a nondisjunction. The conclusion is that the cause of the disorder is most likely a mutation.  ]]> 2017-05-24 20:37:22 UTC https://padlet.com/zurca/bs96h3jizs17/wish/173715144 zurca https://padlet.com/zurca/bs96h3jizs17/wish/173715235 2017-05-24 20:38:06 UTC https://padlet.com/zurca/bs96h3jizs17/wish/173715235 Treatment zurca https://padlet.com/zurca/bs96h3jizs17/wish/173715302 •Progeria has no treatment that can cure the disease but certain medication and therapy to help patients coupe with the symptoms of the disease that reduce complications caused by the disorder. Some drugs like Lonafarnib are being researched and shows promise. ]]> 2017-05-24 20:38:46 UTC https://padlet.com/zurca/bs96h3jizs17/wish/173715302 zurca https://padlet.com/zurca/bs96h3jizs17/wish/173715373 2017-05-24 20:39:20 UTC https://padlet.com/zurca/bs96h3jizs17/wish/173715373 Future Treatment zurca https://padlet.com/zurca/bs96h3jizs17/wish/173715407 •Some of the technology that might be used in the future to fight progeria deal with repair of DNA using methods such as non-homogeus and joining. This future technology may help us fix the part of the affected gene that causes progeria.]]> 2017-05-24 20:39:38 UTC https://padlet.com/zurca/bs96h3jizs17/wish/173715407 zurca https://padlet.com/zurca/bs96h3jizs17/wish/173715480 2017-05-24 20:40:11 UTC https://padlet.com/zurca/bs96h3jizs17/wish/173715480 Extra Credit zurca https://padlet.com/zurca/bs96h3jizs17/wish/173715560
When the gene responsible for LMNA causes a different form of Lamin which affects the cell as it is not originally what it needs. Progeria is not normally family transmitted.  ]]> 2017-05-24 20:40:50 UTC https://padlet.com/zurca/bs96h3jizs17/wish/173715560 zurca https://padlet.com/zurca/bs96h3jizs17/wish/173715621 2017-05-24 20:41:25 UTC https://padlet.com/zurca/bs96h3jizs17/wish/173715621 References zurca https://padlet.com/zurca/bs96h3jizs17/wish/173715668 •"About Progeria." The Progeria Research Foundation. N.p., n.d. Web. 24 May 2017.
•"Progeria." Wikipedia. Wikimedia Foundation, 21 May 2017. Web. 24 May 2017.
•"Progeria." Mayo Clinic. Mayo Foundation for Medical Education and Research, 27 Apr. 2017. Web. 24 May 2017.
•http://www.webmd.com/children/progeria#1. 24 May 2017
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