(Cisneros, 59)

The Vignette explains the slow and sad process of her aunt that got sick and was slowly dying over time. Then she died and no one expected it, they thought the day would never come. 

Luck or Unluckiness
Diseases

Cisneros is conveying a theme of people being born the way they are, no matter if it is fair or not. Cisneros uses this personification to give the disease a human like quality to make the reader see it as evil.

(Cisneros, 60)

The aunt is sick, and she is sort of in her own world, but that is not a good world. Esperanza and her family look at her aunt in a patronizing way, and see her as a sick object.

Open Mindedness
Vulnerability

Cisneros is using this imagery and a metaphorical sense in this line to emphasize the overall theme of helplessness when it comes to sickness and/or mental illnesses.

(Cisneros, 61)

She knew that eventually her time would come and she wanted to give Esperanza a piece of advice that would help her in the future to keep going and push forward. 

Freedom
Literature

Cisneros is using the connotation and denotation definitions of this sentence, to create many interpretations that could mean many things especially from this wise aunt who is about to die and my interpretation of this quote is the aunt is telling Esperanza to, with her writing get free of the cycle of poverty in their family.