https://padlet.com/bernackiclaire/b86yvg5nw43c3erz en-us 2023-03-09 18:28:03 UTC 2025-12-22 13:13:59 UTC hello@padlet.com bernackiclaire https://padlet.com/bernackiclaire/b86yvg5nw43c3erz/wish/2510744129 1. Sympathetic Nervous System : also called: fight, fright, flight; adrenergic
2. Parasympathetic Nervous System: also called: rest and digest; cholinergic]]> 2023-03-09 18:31:57 UTC https://padlet.com/bernackiclaire/b86yvg5nw43c3erz/wish/2510744129 bernackiclaire https://padlet.com/bernackiclaire/b86yvg5nw43c3erz/wish/2510748062 1. Sympathetic Nervous System: Norepinephrine, Epinephrine, Dopamine
2. Parasympathetic Nervous System: Acetylcholine, Dopamine]]> 2023-03-09 18:34:57 UTC https://padlet.com/bernackiclaire/b86yvg5nw43c3erz/wish/2510748062 bernackiclaire https://padlet.com/bernackiclaire/b86yvg5nw43c3erz/wish/2510754972 1. Acetylcholine- at ganglia from presynaptic nerve endings 
2. Norepinephrine- at postganglionic nerve endings at adrenal medulla and neurons
3. Epinephrine- produced by adrenal medulla acting on adrenergic receptiors
3. Dopamine- since it is a precursor for NE, it is released from postganglionic nerve endings at adrenal medulla and neurons]]> 2023-03-09 18:39:55 UTC https://padlet.com/bernackiclaire/b86yvg5nw43c3erz/wish/2510754972 bernackiclaire https://padlet.com/bernackiclaire/b86yvg5nw43c3erz/wish/2510764859 Sympathetic Receptors:
1. Alpha 1- found on glands, smooth muscles, eyes, most arteries and veins
2. Alpha 2- smooth muscle (relaxation/inhibition)
3. Beta 1- on heart
4. Beta 2- smooth muscle, lungs, uterus, skeletal muscle arteries, coronary arteries

Parasympathetic Receptors:
1. Muscarinic- on cardiac, smooth muscle, and glands
2. Nicotinic 1- at ganglia of parasympathetic nerves and sympathetic nerves (synapse area)
3. Nicotinic 2- somatic, neuromuscular junction of skeletal muscle

]]> 2023-03-09 18:47:44 UTC https://padlet.com/bernackiclaire/b86yvg5nw43c3erz/wish/2510764859 bernackiclaire https://padlet.com/bernackiclaire/b86yvg5nw43c3erz/wish/2510781408 Sympathetic Receptors:
1. Alpha 1- found on glands, smooth muscles, eyes, most arteries and veins
Response: smooth muscle contraction and vasoconstriction increases BP, mydriasis

2. Alpha 2- smooth muscle (relaxation/inhibition)
Response: parasympathetic response, decreases contraction of smooth muscle lowers BP, negative feedback system
3. Beta 1- on heart
Response: increase force of contraction, heart rate, conduction
4. Beta 2- smooth muscle, lungs, uterus, skeletal muscle arteries, coronary arteries
Response: smooth muscle relaxation, bronchodilation, uterine relaxation, relaxation of coronary arteries and skeletal muscle blood vessels

Parasympathetic Receptors:
1. Muscarinic- on cardiac, smooth muscle, and glands
Response: decrease heart rate, bronchoconstriction, increase digestions, increase GI secretions, increase urination, pupillary constriction
2. Nicotinic 1- at ganglia of parasympathetic nerves and sympathetic nerves (synapse area)
3. Nicotinic 2- somatic, neuromuscular junction of skeletal muscle
Response: muscle contraction]]> 2023-03-09 19:00:50 UTC https://padlet.com/bernackiclaire/b86yvg5nw43c3erz/wish/2510781408 bernackiclaire https://padlet.com/bernackiclaire/b86yvg5nw43c3erz/wish/2510810642 ANS:
1. Alpha-1: Adrenergic Agonist
Receptor: alpha-1 receptor
MOA: contraction of smooth muscle, blood vessels constrict, increase BP, vasoconstriction of nasal passages
2. Adrenergic Agonists
Receptor: alpha and beta receptors
MOA: vasoconstriction, cardiac stimulant, bronchodilator
3. Alpha-1: Adrenergic Blocking Drugs
Receptor: alpha-1 receptors 
MOA: relaxation of smooth muscle, vasodilation of blood vessels, decrease BP, relaxes smooth muscle of ureters and increases urine flow
4. Beta Adrenergic Agonists
Receptor: dopaminergic, beta-1, alpha-1 receptors
MOA: (low)vasodilation and increased renal blood flow; (moderate) increased contraction and cardiac output, (high) vasoconstriction
5. Beta Adrenergic Agonists
Receptor: beta-2 receptors
MOA: relax smooth muscle of the lungs and uterus
6. Beta Adrenergic Blocking Drugs (selective and nonselective)
Receptor: (selective) beta-1 receptor, (nonselective) beta-1 and 2
MOA: beta-1 receptor blocked, decrease contraction and cardiac output, decrease heart rate, decrease conduction, decrease BP, can also caue bronchoconstriction (nonselective)

PNS:
1. Direct- Acting Cholinergic Agonists
Receptor: muscarinic 
MOA: mimic Acetylcholine
2. Indirect- Acting Cholinergic Agonists (Parasympathomimetics)
Receptor: not direct acting
MOA: inhibits acetylcholinesterase, increase ACH
3. Anticholinergics/parasympatholytics
Receptor: cholinergic receptors
MOA: blocking drugs, competitive antagonism

]]> 2023-03-09 19:24:35 UTC https://padlet.com/bernackiclaire/b86yvg5nw43c3erz/wish/2510810642 bernackiclaire https://padlet.com/bernackiclaire/b86yvg5nw43c3erz/wish/2510819294 ANS:
1. Alpha-1 Adrenergic Agonists
ephedrine
phenylephrine (Neo-Synephrine)
2. Adrenergic Agonists
epinephrine (Adrenalin)
3. Alpha-1 Adrenergic Blockers
prazosin (Minipress)
terazosin (Hytrin)
doxazosin (Cardura)
4. Beta-1 Adrenergic Agonists
dobutamine
5. Beta-2 Adrenergic Agonists
formoterol (Foradil)
albuterol (Proventi, Ventonlin)
terbutaline (Brethine)
6. Beta Blockers
Nonselective: nadolol (Corgard), propranolol (Inderal), timolol (Blocadren)
Selective: atenolol (Tenormin), metoprolol (Lopressor)
7. Direct Acting Cholinergic Agonist
acetylcholine
pilocarpine (Pilocar)
bethanechol (Urecholine)
8. Indirect Acting Cholinergic Agents
neostigmine (Prostigmin)
9. Anticholinergics
atropine
dicyclomine (Bentyl)

PNS:
1. Skeletal Muscle Relaxants
Peripherally- succinylcholine, recuronium bromide (Zemuron), dantrolene (Dantrium)
Centrally- cyclobenzaprine (Flexeril), carisoprodol (Soma), methocarbamol (Robaxin), orphenadrine citrate (Norflex), chlorzoxazone (Parafon Forte DSC), metaxaolne (Skelaxin)


]]> 2023-03-09 19:32:06 UTC https://padlet.com/bernackiclaire/b86yvg5nw43c3erz/wish/2510819294 bernackiclaire https://padlet.com/bernackiclaire/b86yvg5nw43c3erz/wish/2510819749 Powerpoints:
ANS Part 1
ANS Part 2

Unit 2 Drug List]]> 2023-03-09 19:32:31 UTC https://padlet.com/bernackiclaire/b86yvg5nw43c3erz/wish/2510819749