https://padlet.com/carlin_hurst/b0mupmdut65e TransMedics Organ Care System en-us 2017-10-07 22:43:20 UTC 2025-11-14 16:56:17 UTC hello@padlet.com carlin_hurst https://padlet.com/carlin_hurst/b0mupmdut65e/wish/194946877 2017-10-07 22:48:38 UTC https://padlet.com/carlin_hurst/b0mupmdut65e/wish/194946877 carlin_hurst https://padlet.com/carlin_hurst/b0mupmdut65e/wish/194947010 Currently, cold organ preservation is the standard of care in heart transplantation (Stamp et al., 2015). This method leads to increased myocardial ischemia and limits potential donors related to time. The TransMedics Organ Care System is revolutionizing the world of heart transplant. This is the first system that allows donor hearts to remain beating in a warm (34 degrees Celsius), perfused, and oxygenated state (Stamp et al., 2015). This allows for longer travel time from donor to recipient and helps to reduce the adverse effects from cold preservation. This could decrease the body's chances of rejecting the donor heart. This advancing technology could help to save more lives and lead to better patient outcomes. ]]> 2017-10-07 22:53:06 UTC https://padlet.com/carlin_hurst/b0mupmdut65e/wish/194947010 carlin_hurst https://padlet.com/carlin_hurst/b0mupmdut65e/wish/194947369 -Reduction in total cold ischemic time of the heart
-Out of body time increased to at least 8 hours
-Increased donor options 
-Decreased organ rejection
-System is able to detect coronary artery disease without angiography
-Improved outcomes for patients with left ventricular assistive devices]]> 2017-10-07 23:05:02 UTC https://padlet.com/carlin_hurst/b0mupmdut65e/wish/194947369 carlin_hurst https://padlet.com/carlin_hurst/b0mupmdut65e/wish/194947763 -Increased out of body time can cause increased lactate levels
-Longer out of body times may still lead to decrease left ventricular function in some donor hearts
-Potential for hemolysis in the system
-Expensive]]> 2017-10-07 23:16:10 UTC https://padlet.com/carlin_hurst/b0mupmdut65e/wish/194947763 carlin_hurst https://padlet.com/carlin_hurst/b0mupmdut65e/wish/194948015 Saez, D. G., Zach, B., Sabashnikov, A., Bowles, C. T., De Robertis, F., Mohite, P. N., Propov, A., . . . Simon, A. R. (2014). Evaluation of the organ care system in heart transplantation with an adverse donor/recipient profile. The Society of Thoracic Surgeons, 98(6), 2099-2106. doi: 10.1016/j.athoracsur.2014.06.098

Stamp, N. L., Shah, A., Vincent, V., Wright, B., Wood, C., Pavey, W., Cokis, C., . . . Larbalestier, R. (2015). Successful heart transplant after ten hours out-of-body time using the transmedics organ care system. Heart, Lung and Circulation, 24, 611-613. doi: 10.1016/j.hlc.2015.01.005]]> 2017-10-07 23:25:11 UTC https://padlet.com/carlin_hurst/b0mupmdut65e/wish/194948015