Allergies by https://padlet.com/jonasklimpfinger/awz4169i873lbgo8 en-us 2024-03-19 17:56:22 UTC 2024-03-20 15:16:32 UTC hello@padlet.com Allergies in general: jonasklimpfinger https://padlet.com/jonasklimpfinger/awz4169i873lbgo8/wish/2926105319

  • autoimmune disease

  • not caused by bacteria/viruses

  • immune response against nonpathogenic antigens = allergens

  • 4 Types of allergic reactions (Type I-IV)

    • most common: Type I

    • immediate allergic reaction through IgE-antibodies

  • common types of allergies:

    • dust allergies (dust mites, mold)

    • pollen allergies (hay fever)

    • food allergies (peanut,milk)

    • ]]>     2024-03-20 02:35:42 UTC https://padlet.com/jonasklimpfinger/awz4169i873lbgo8/wish/2926105319     Hay fever and milk allergy jonasklimpfinger https://padlet.com/jonasklimpfinger/awz4169i873lbgo8/wish/2926183236

  • Type I hypersensitivity

  • hay fever:

    • caused by various types of pollen

    • birch pollen: main allergen Bet v 1

    • cross reactions with other allergens due to similar structure (apple/hazelnut)

  • milk allergy:

    • caused by beta-lactoglobulin (BLG)

    • not lactose intolerance - often gets mixed up

    • ]]>     2024-03-20 03:33:10 UTC https://padlet.com/jonasklimpfinger/awz4169i873lbgo8/wish/2926183236     Allergens and antibodies jonasklimpfinger https://padlet.com/jonasklimpfinger/awz4169i873lbgo8/wish/2926209201

  • Allergen enters body

  • Antigene presenting cell (APC) absorbs allergen through phagocytosis

  • presents allergen to T-helper cell

  • T-helper cell activates B-cell

    • -> production of IgE-antibodies

  • Antibody binds to Allergen

    • -> binds to IgE receptor on mast cells

  • Mast cells produce Mediators (substances, that trigger inflammation) such as Histamines

    • ]]>     2024-03-20 03:57:35 UTC https://padlet.com/jonasklimpfinger/awz4169i873lbgo8/wish/2926209201     Symptoms jonasklimpfinger https://padlet.com/jonasklimpfinger/awz4169i873lbgo8/wish/2926236146 hay fever:

    • red, itchy and teary eyes

    • skin irritations

    • nasal itching/sneezing

    • shortness of breath/coughing

    milk allergy:

    • stomach cramps/vomiting

    • difficulty breathing

    • dizziness/ faint feeling

    • anaphylactic shock



    ]]>     2024-03-20 04:23:10 UTC https://padlet.com/jonasklimpfinger/awz4169i873lbgo8/wish/2926236146     Environmental factors jonasklimpfinger https://padlet.com/jonasklimpfinger/awz4169i873lbgo8/wish/2926249544 depends on the type of allergy


    • state of the immune system

    • age

    hay fever:

    • amount of pollen in the air

    • other forms of air pollution

    • smoking habits

    ]]>     2024-03-20 04:36:43 UTC https://padlet.com/jonasklimpfinger/awz4169i873lbgo8/wish/2926249544     Allergy Treatments jonasklimpfinger https://padlet.com/jonasklimpfinger/awz4169i873lbgo8/wish/2926259881 Immunotherapy

    • long term treatments

    • subcutaneous immunotherapy (SCIT)

    • sublingual immunotherapy (SLIT)

    Allergy medicine:

    • to reduce symptoms

    • Steroids

    • Antihistamines

    • Epinephrine shots

    • iron dependency

    ]]>     2024-03-20 04:46:29 UTC https://padlet.com/jonasklimpfinger/awz4169i873lbgo8/wish/2926259881     Austrian involvement jonasklimpfinger https://padlet.com/jonasklimpfinger/awz4169i873lbgo8/wish/2926265672 Messerli institute:

    • University of Veterinary Medicine, Vienna

    • Researchgroup for comparative medicine

    • research of similarities between allergies in animals and humans

    ]]>     2024-03-20 04:52:11 UTC https://padlet.com/jonasklimpfinger/awz4169i873lbgo8/wish/2926265672     Sources jonasklimpfinger https://padlet.com/jonasklimpfinger/awz4169i873lbgo8/wish/2926303801

    Takenori Inomata, et al.; (2022); "Individual characteristics and associated factors of hay fever: A largescale mHealth study using AllerSearch"; Allergology International; Vol. 71, Issue 3; p.325-334


    (2020), "Allergens and Pollen", https://www.cdc.gov/climateandhealth/effects/allergen.htm [19.03.2024]


    Lori M. King, Sylvia Davis; (2023); "Allergies: Symptoms, Causes, Diagnosis, and Treatment"; https://www.webmd.com/allergies/allergy-symptoms#1-2 [19.03.2024]


    S. Jossé, „Kuhstallpille bei Allergie: Hilft Immunstärkung vom Bauernhof?“, https://www.mein-allergieportal.com/darmflora-mikrobiom/2005-immunstaerkung-vom-bauernhof-mit-derkuhstallpille-dem-mikrobiom-helfen.html [19.03.2024]


    F. Roth-Walter, E. Jensen-Jarolim, C. Gómez-Casado et al., „Bet v 1 from Birch Pollen Is a Lipocalin-like Protein Acting as Allergen Only When Devoid of Iron by Promoting Th2 Lymphocytes“, https://www.researchgate.net/figure/Structural-comparison-of-Bet-v-1-with-humanLCN-2-a-structural-comparison-of-crystal_fig2_262072232 [18.03.2024]


    vetmeduni Messerli Forschungsinstitut, https://www.vetmeduni.ac.at/messerli-forschungsinstitut


    Figure 1: Jeffrey K Actor; (2023) "Introductory Immunology", Academic Press; p. 123-131



    ]]>     2024-03-20 05:24:07 UTC https://padlet.com/jonasklimpfinger/awz4169i873lbgo8/wish/2926303801     Feedback lorettah284 https://padlet.com/jonasklimpfinger/awz4169i873lbgo8/wish/2926821104 -well organized information blocks with the arrows

    - very well researched, many sources

    - fluent, well structured and dynamic free speech

    Marlene and Loretta

    ]]>     2024-03-20 13:01:20 UTC https://padlet.com/jonasklimpfinger/awz4169i873lbgo8/wish/2926821104