Brain's stress/antistress and addiction by

Heuristic framework

sutphins1 — 2024-04-23 21:31:49 UTC

Impulsivity dominates the early stages of addiction, and compulsivity dominates the later terminal stages.

Understanding the role of the brain's stress and antistress systems in addiction provides:

sutphins1 — 2024-04-23 21:40:15 UTC

A population for treatment.
Prevention of addiction.
Insights into the organization and function of basic brain emotional circuitry.

Key features of addiction such as: reward anticipation, cravings, negative affect, and impaired executive functions are

sutphins1 — 2024-04-23 21:48:42 UTC

sutphins1 — 2024-04-23 21:56:12 UTC

An allostatic view is defined as allostasis or stability through change and has most often been connected to challenges with homeostasis.

"Addiction and stress: an allostatic view."

sutphins1 — 2024-04-23 22:07:01 UTC

Repeated life stressors with no "down time" can lead to disease or a diseased type of state.

Conclusion

sutphins1 — 2024-04-23 22:16:17 UTC

Understanding addiction

sutphins1 — 2024-04-30 23:14:43 UTC

Brain's stress/antistress systems and addiction.

sutphins1 — 2024-04-30 23:15:17 UTC

Addiction and stress: An allostatic View.

sutphins1 — 2024-04-30 23:15:50 UTC

Addiction is a chronically relapsing disorder identified by compulsive drug use and loss of control over drug intake.

sutphins1 — 2024-04-30 23:18:11 UTC

Addiction is a complex, and chronic condition that involves both biological and psychological factors.

CRF

sutphins1 — 2024-04-30 23:27:48 UTC

Stress leads to changes in corticotropin-releasing factors (CRF) in the brains that impacts addiction.

sutphins1 — 2024-04-30 23:32:30 UTC

Once an individual's addiction moves from impulsivity to compulsivity a shift happens from positive reinforcement, driving the motivated behavior to negative reinforcement.

Rats were used as test subjects.

sutphins1 — 2024-05-01 20:13:14 UTC

Animal models were giving specific drugs; such as stimulants, opioids, alcohol, nicotine, and THC.

The Neurobiology of addiction has been studied a lot and researchers came up with a Heuristics Framework that helps understand the different stages of addiction.

sutphins1 — 2024-05-01 20:40:14 UTC

Stage 1 of addiction

sutphins1 — 2024-05-02 23:09:28 UTC

Binge/Intoxication-

During this phase the individual takes a substance that makes them experience intense euphoria.

Stage 2 of addiction-

sutphins1 — 2024-05-02 23:25:27 UTC

Withdrawal/Negative Affect-

After the pleasurable experience of using substances, the individual experiences withdrawal and negative feeling start to arise.

Stage 3 of addiction-

sutphins1 — 2024-05-02 23:31:27 UTC

Preoccupation/Anticipation (Craving)-

The individual's focus is on obtaining the substance to help stop the negative feelings that they are feeling from withdrawing from drugs, and their own uncomfortable emotions.

The brains stress system-

sutphins1 — 2024-05-02 23:48:52 UTC

Plays a critical role in the pathophysiology of drug addiction.

Tests were measured by the rats:

sutphins1 — 2024-05-09 20:54:19 UTC

increasing their own drug intake, and how the rats would work harder to get their substance.

Test Subjects

sutphins1 — 2024-05-09 20:56:21 UTC