MALT TUTORIAL by Chiazor Nwokoma https://padlet.com/w1648398/ad3ns9022ldm Skin associated lympoid tissue. en-us 2018-02-23 11:24:16 UTC 2025-10-21 00:41:29 UTC hello@padlet.com S.A L. T w1648398 https://padlet.com/w1648398/ad3ns9022ldm/wish/242753675 2018-03-16 11:32:31 UTC https://padlet.com/w1648398/ad3ns9022ldm/wish/242753675 Notes w1648398 https://padlet.com/w1648398/ad3ns9022ldm/wish/242755336 - The skin is a site for the presentation of antigens to T cells. It's involvement in immune response via mucosal surfaces classifies it to be a lymphoid associated organ.

- it functions as a peripheral lymphoid tissue.

- The skin has APC's and memory cells that reside within it. As a result, when an antigen enters into the skin initially, it is engulfed by APCS and subsequently presented to memory cells.

- On second encounter, the presence of these memory cells  trigger an inflammatory response in a phase known as the challenge phase ( the two phases are represented in figure below)]]> 2018-03-16 11:37:37 UTC https://padlet.com/w1648398/ad3ns9022ldm/wish/242755336 w1632538 https://padlet.com/w1648398/ad3ns9022ldm/wish/242763661 WileyPLUS textbook]]> 2018-03-16 11:59:59 UTC https://padlet.com/w1648398/ad3ns9022ldm/wish/242763661 References w1634591 https://padlet.com/w1648398/ad3ns9022ldm/wish/242764290 Streilein, J.W., 1989. Skin-associated lymphoid tissue. Immunology series, 46, pp.73-96.]]> 2018-03-16 12:01:56 UTC https://padlet.com/w1648398/ad3ns9022ldm/wish/242764290 References w1668508 https://padlet.com/w1648398/ad3ns9022ldm/wish/242764869 Egawa, G. and Kabashima, K. (2011). Skin as a Peripheral Lymphoid Organ: Revisiting the Concept of Skin-Associated Lymphoid Tissues. Journal of Investigative Dermatology, 131(11), pp.2178-2185.

Toews, G., Bergstresser, P. and Streilein, J. (1980). Langerhans Cells: Sentinels of Skin Associated Lymphoid Tissue. Journal of Investigative Dermatology, 75(1), pp.78-82.]]> 2018-03-16 12:03:50 UTC https://padlet.com/w1648398/ad3ns9022ldm/wish/242764869 w1648398 https://padlet.com/w1648398/ad3ns9022ldm/wish/242765504 2018-03-16 12:05:50 UTC https://padlet.com/w1648398/ad3ns9022ldm/wish/242765504 w1648398 https://padlet.com/w1648398/ad3ns9022ldm/wish/242766815 2018-03-16 12:09:31 UTC https://padlet.com/w1648398/ad3ns9022ldm/wish/242766815 w1634591 https://padlet.com/w1648398/ad3ns9022ldm/wish/242767175 2018-03-16 12:10:32 UTC https://padlet.com/w1648398/ad3ns9022ldm/wish/242767175 w1648398 https://padlet.com/w1648398/ad3ns9022ldm/wish/242773733 2018-03-16 12:27:03 UTC https://padlet.com/w1648398/ad3ns9022ldm/wish/242773733