Pharmacology Discussion Board #2 by Morgan Van Norman https://padlet.com/morganvannorman1/a56muq9xqwx5f3ju Source: Unit 2 Lecture Materials and Pharmacology Text en-us 2023-02-12 23:11:43 UTC 2025-11-08 08:21:53 UTC hello@padlet.com (1) Autonomic Nervous System (ANS) morganvannorman1 https://padlet.com/morganvannorman1/a56muq9xqwx5f3ju/wish/2478138477 Two Divisions:
Sympathetic (SNS)
("Fight or Flight")
Parasympathetic (PNS)
("Rest & Digest")


]]> 2023-02-12 23:17:58 UTC https://padlet.com/morganvannorman1/a56muq9xqwx5f3ju/wish/2478138477 (2-5-A) Sympathetic Neurotransmitters: Locations, Receptors, Organs & Responses morganvannorman1 https://padlet.com/morganvannorman1/a56muq9xqwx5f3ju/wish/2478150400
Neurotransmitters:
Adrenergic Nerves Release:
    norepinephrine (NE)
Adrenal Medulla Releases:
    epinephrine (EPI)
NE & EPI Target
Adrenergic Receptors:
    Alpha 1 & 2
    Beta 1 & 2

]]> 2023-02-12 23:45:50 UTC https://padlet.com/morganvannorman1/a56muq9xqwx5f3ju/wish/2478150400 (2-5-B) Parasympathetic Neurotransmitters: Locations, Receptors, Organs & Responses morganvannorman1 https://padlet.com/morganvannorman1/a56muq9xqwx5f3ju/wish/2478153712 Neurotransmitter:
Cholinergic Neurons Release:
      acetylcholine (AcH)
AcH Targets Cholinergic Receptors:
Muscarinic
Cardiac, Smooth Muscle & Glands
Nicotinic 1 (Nn)
PNS nerve ganglia & SNS nerve synapses
Nicotinic 2 (Nm)
Somatic & NMJ of Skeletal Muscle]]> 2023-02-12 23:54:05 UTC https://padlet.com/morganvannorman1/a56muq9xqwx5f3ju/wish/2478153712 (6-A) Sympathetic Division: Drug Classifications, Receptors & MOA morganvannorman1 https://padlet.com/morganvannorman1/a56muq9xqwx5f3ju/wish/2478164561 Source: Unit 2 ANS Part I Lecture Slides:

Alpha-1 Adrenergic Agonists @
Alpha-1 Receptors -->
muscle contraction, vasoconstriction, ++ BP, decongestant

Alpha-1 Adrenergic Blocker @
Alpha-1 Receptors -->
muscle relaxant, vasodilation, -- BP, ++ urine output

Beta-1 Adrenergic Agonists@
Beta-1 Receptors -->
(Low) dopaminergic stimulant, ++ renal BF
(Mod) heart stimulant, ++ FOC/CO
(High) vasoconstrictor, ++ BP

Beta-2 Adrenergic Agonists@
Beta-2 Receptors -->
lung, uterus muscle relaxant, bronchodilator

Selective Beta-1 Blockers@
Beta-1 Receptors -->
-- FOC, HR, CO, BP and conduction

Non-Selective Beta Blockers@
ALL Beta Receptors -->
-- FOC, HR, CO, BP and conduction, bronchoconstrictor

Adrenergic Agonists @
ALL Alpha & Beta Receptors -->
vasoconstriction, ++ BP, cardiac stimulant, bronchodilator

]]> 2023-02-13 00:16:51 UTC https://padlet.com/morganvannorman1/a56muq9xqwx5f3ju/wish/2478164561 (6-B) Parasympathetic Division: Drug Classifications, Receptors & MOA morganvannorman1 https://padlet.com/morganvannorman1/a56muq9xqwx5f3ju/wish/2480051617 Source: Unit 2 ANS Part II Lecture Slides

Direct Acting Cholinergic Agonists@
Muscarinic Receptors -->
mimics AcH = pupil constriction, bladder & GI tract stimulation

Indirect Acting Cholinergic Agonists@
Muscarinic Receptors -->
inhibits acetylcholinesterase to ++ AcH

Anti-Cholinergics (Parasympatholytics)@
Cholinergic Receptors -->
competitive antagonism w/ other drugs]]> 2023-02-13 18:14:36 UTC https://padlet.com/morganvannorman1/a56muq9xqwx5f3ju/wish/2480051617 (7-A) Sympathetic Division: Specific Drug Examples morganvannorman1 https://padlet.com/morganvannorman1/a56muq9xqwx5f3ju/wish/2480057845 Source: Unit 2 Drug List

Alpha-1 Adrenergic Agonists @
Alpha-1 Receptors -->
   ephedrine
   phenylephrine (Neo-Synephrine)

Alpha-1 Adrenergic Blocker @
Alpha-1 Receptors -->
   prazosin (Minipress)
   terazosin (Hytrin)
   doxazosin (Cardura)

Beta-1 Adrenergic Agonists@
Beta-1 Receptors -->
   dobutamine

Beta-2 Adrenergic Agonists@
Beta-2 Receptors -->
   formoterol (Foradil)
   albuterol (Proventil / Ventolin)
   terbutaline (Brethine)

Selective Beta-1 Blockers@
Beta-1 Receptors -->
   atenolol (Tenormin)
   metoprolol (Lopressor)

Non-Selective Beta Blockers@
ALL Beta Receptors -->
   nadolol (Corgard)
   propranolol (Inderal)
   timolol (Blocadren)
   
Adrenergic Agonists @
ALL Alpha & Beta Receptors -->
   epinephrine (Adrenalin)]]> 2023-02-13 18:18:46 UTC https://padlet.com/morganvannorman1/a56muq9xqwx5f3ju/wish/2480057845 (7-B) Parasympathetic Division: Specific Drug Examples morganvannorman1 https://padlet.com/morganvannorman1/a56muq9xqwx5f3ju/wish/2480067427 Source: Unit 2 Drug List

Direct Acting Cholinergic Agonists@
Muscarinic Receptors -->
   acetylcholine (AcH)
   pilocarpine (Pilocar)
   bethanechol (Urecholine)

Indirect Acting Cholinergic Agonists@
Muscarinic Receptors -->
   neostigmine (Prostigmin)

Anti-Cholinergics (Parasympatholytics)@
Cholinergic Receptors -->
   atropine
   dicyclomine (Bentyl)]]> 2023-02-13 18:25:34 UTC https://padlet.com/morganvannorman1/a56muq9xqwx5f3ju/wish/2480067427 (7-C) Somatic System: Specific Drug Examples morganvannorman1 https://padlet.com/morganvannorman1/a56muq9xqwx5f3ju/wish/2480071698 Source: Unit 2 Drug List

Peripheral - Skeletal Muscle Relaxants:

Depolarizing:
succinylcholine
Non-Depolarizing:
rocuronium bromide (Zemuron)
Direct Acting:
dantrolene (Dantrium)

Central - Skeletal Muscle Relaxants:
cyclobenzaprine (Flexeril)
carisoprodol (Soma)
methocarbamol (Robaxin)
orphenadrine citrate (Norflex)
chlorzoxazone (Parafon Forte DSC)
metazalone (Skelaxin)]]> 2023-02-13 18:28:34 UTC https://padlet.com/morganvannorman1/a56muq9xqwx5f3ju/wish/2480071698 (7-D) Respiratory System: Specific Drug Examples morganvannorman1 https://padlet.com/morganvannorman1/a56muq9xqwx5f3ju/wish/2480097909 Source: Unit 2 Drug List

Mast Cell Stabilizers:
cromolyn sodium (Intal / Nasalcrom)

Bronchodilators:

Sympathomimetics / Beta-2 Agonists
albuterol (Proventil / Ventolin)
formoterol (Foradil)
terbutaline (Brethine)
salmeterol (Serevent)

Xanthine Derivative:
theophylline (Theo-Dur)
aminophylline (Paladron)

Cysteinyl Leukotriene Receptor Inhibitor:
montelukast (Singulair)

Anticholinergic:
ipratropium bromide (Atrovent)

Combination Bronchodilator:
ipratropium bromide + albuterol sulfate (Combivent)

Antihistamines:

Generation I: (Sedatives)
brompheniramine (Dimetapp)
chlorpheniramine (Chlor-Trimeton)
clemastine (Tavist)
diphenhydramine (Benadryl)
hydroxyzine (Atarax)
promethazine (Phenergan)
azelastine (Asterlin / Astepro)

Generation II: (Non-Sedating)
loratadine (Claritin)
fexofenadine (Allegra)
cetirizine (Zyrtec)

Corticosteroids:
budesonide (Rhinocort / Pulmicort)
mometasone (Nasonex / Asmanex)
fluticasone (Flonase / Flovent)
flunisolide (Nasalide)
triamcinolone (Nasacort / Azmacort)

Antitussives

Narcotic:
hydrocodone (Hycodan)
codeine/guaifenesin (Robitussin AC)

Non-Narcotic:
dextromethorphan/guaifenesin (Robitussin DM)
benzonatate (Tessalon Perles)

Decongestants:
oxymetazoline (Afrin)
pheniramine (Dristan)
phenylephrine (Neo-Synephrine)
pseudoephedrine (Sudafed)

Expectorant:
guaifenesin (Robitussin / Mucinex / Organidin)]]> 2023-02-13 18:46:54 UTC https://padlet.com/morganvannorman1/a56muq9xqwx5f3ju/wish/2480097909