Critically analyse, with supporting evidence, whether the gastrointestinal tract is appropriately designed for its physiological functions by

Critically analyse, with supporting evidence, whether the gastrointestinal tract is appropriately designed for its physiological functions by https://padlet.com/dilewis2/a2ajawac4aia en-us 2020-01-24 08:54:59 UTC 2025-12-09 11:51:02 UTC hello@padlet.com https://padlet.com/dilewis2/a2ajawac4aia/wish/439685428 I'm online now (3.15) & available to answer any questions
Dr Lewis]]> 2020-02-03 15:17:18 UTC https://padlet.com/dilewis2/a2ajawac4aia/wish/439685428 would GIT disorders like coeliac disease/gallstones be relevant? https://padlet.com/dilewis2/a2ajawac4aia/wish/439686194 2020-02-03 15:18:11 UTC https://padlet.com/dilewis2/a2ajawac4aia/wish/439686194 failure of the gastroesophageal sphincter allows stomach acid to flow up the oesophagus which does not have the protective mucus of the stomach so is susceptible to damage https://padlet.com/dilewis2/a2ajawac4aia/wish/439694504 2020-02-03 15:27:10 UTC https://padlet.com/dilewis2/a2ajawac4aia/wish/439694504 Anybody else got any thoughts? https://padlet.com/dilewis2/a2ajawac4aia/wish/439708826 2020-02-03 15:44:01 UTC https://padlet.com/dilewis2/a2ajawac4aia/wish/439708826 small intestine is designed to have a large surface area for maximum absorption- villi and microvilli https://padlet.com/dilewis2/a2ajawac4aia/wish/439709581 2020-02-03 15:44:58 UTC https://padlet.com/dilewis2/a2ajawac4aia/wish/439709581 strongly advise you work in teams on this to share workload, bounce ideas of each other & therefore really come up with evidence informed essay with lots of indepth critical analysis https://padlet.com/dilewis2/a2ajawac4aia/wish/439710968 2020-02-03 15:46:37 UTC https://padlet.com/dilewis2/a2ajawac4aia/wish/439710968 please could you give an example of a feedforward -ve neural reflex and a feedback +ve neural reflex https://padlet.com/dilewis2/a2ajawac4aia/wish/439723630 2020-02-03 16:01:58 UTC https://padlet.com/dilewis2/a2ajawac4aia/wish/439723630 the gut microbiota and how it has a lot of opportunistic pathogens that can cause disease if they get out of the GIT, but we need them for protection/digestion https://padlet.com/dilewis2/a2ajawac4aia/wish/439724288 2020-02-03 16:02:57 UTC https://padlet.com/dilewis2/a2ajawac4aia/wish/439724288 Motility https://padlet.com/dilewis2/a2ajawac4aia/wish/439729498 appropriately designed as smooth muscle has multiple ways to be regulated (intrinsic and extrinsic neural and humoral), however not always appropriate as can cause problems e.g. IBS

I dont really understand how pharmacology is relevant to the question?]]> 2020-02-03 16:10:12 UTC https://padlet.com/dilewis2/a2ajawac4aia/wish/439729498 https://padlet.com/dilewis2/a2ajawac4aia/wish/439729704 I am not sure i understand the question. Do you want us to talk about situation when its design fail and stops it from doing its normal function? Or do you want us to research on how it is appropriate or can be improved for its basic functions?

]]> 2020-02-03 16:10:28 UTC https://padlet.com/dilewis2/a2ajawac4aia/wish/439729704 https://padlet.com/dilewis2/a2ajawac4aia/wish/439737717 Pyloric valve of the stomach is designed in a way that will allow small portion of chyme into the small intestine each time. This will allow enough time for the acidic chyme to mix with the alkaline juices in the duodenum. However sometimes (pyloric stenosis) the valve thickens -> so it will not allow the passage of chyme into the Small intestine. This may lead to vomiting. ]]> 2020-02-03 16:21:08 UTC https://padlet.com/dilewis2/a2ajawac4aia/wish/439737717 Can you talk about the spleen as it has immune function but is vulnerable to damage due to its anatomical location, however it isn't directly involved in digestion. https://padlet.com/dilewis2/a2ajawac4aia/wish/439744178 2020-02-03 16:29:17 UTC https://padlet.com/dilewis2/a2ajawac4aia/wish/439744178 https://padlet.com/dilewis2/a2ajawac4aia/wish/439746084 Can you talk about the hormones released by the GI tract as part of regulation?]]> 2020-02-03 16:31:50 UTC https://padlet.com/dilewis2/a2ajawac4aia/wish/439746084 Signing off now. Will be back later this evening or overnight. Look at my answers to other questions for a steer as to what we are after. Appreciate that some of you are struggling but we are trying to get you to apply knowledge to critical thinking/problem solving exercise. Hence why suggested you work in teams https://padlet.com/dilewis2/a2ajawac4aia/wish/439746199 2020-02-03 16:31:59 UTC https://padlet.com/dilewis2/a2ajawac4aia/wish/439746199 https://padlet.com/dilewis2/a2ajawac4aia/wish/439748992 Normal: The LES will contract to stop the stomach content to move up the oesophagus

Failure: Acid reflux – the sphincter fails to shut and so the acidic chyme will move up the oesophagus

How: the LES relaxes in the wrong time – it can happen because of disorders but other factors such as the type of the food or pregnancy or being overweight can also have an effect. Some medications such as muscle relaxants may also cause this.

Consequences: heartburn – bloating -

]]> 2020-02-03 16:35:34 UTC https://padlet.com/dilewis2/a2ajawac4aia/wish/439748992 https://padlet.com/dilewis2/a2ajawac4aia/wish/440787332 When you say you want evidence; do you want us to find research papers that shows what happens in a case when the feature we want to talk about it not functioning as it should? Or just examples of diseases the occur from the disfunction and the effect this has?]]> 2020-02-05 08:40:09 UTC https://padlet.com/dilewis2/a2ajawac4aia/wish/440787332 https://padlet.com/dilewis2/a2ajawac4aia/wish/441488869 can we talk about one organ of the GI tract, or can we focus on few examples of regulation in the Gi tract ? ]]> 2020-02-06 12:45:21 UTC https://padlet.com/dilewis2/a2ajawac4aia/wish/441488869 https://padlet.com/dilewis2/a2ajawac4aia/wish/441594542 if we focused on regulation of the GI tract - would this have to be further focused on either hormonal/neural regulation - and would this have to focused onto specific areas of the GI tract?

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