Wilson's Disease by extreme_ peridot https://padlet.com/extreme_peridot/9ldjwhcd1t52 en-us 2017-04-18 05:03:51 UTC 2025-09-24 13:16:26 UTC hello@padlet.com What extreme_peridot https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/166674129
  • Autosomal recessive disease
  • Causes body to not regulate copper production
  • Located on chromosome 13
    • ]]>     2017-04-18 05:05:47 UTC https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/166674129     extreme_peridot https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167409309 2017-04-21 02:55:19 UTC https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167409309 History extreme_peridot https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167409639
  • Named after Samuel Alexander Kinner Wilson (1912)
  • Wlison drew from reports by Carl Westphel (1883), William Gowers (1888), and Adolph Strumpell
  • John Nathaniel Cummings linked copper accumulation in the liver and brain (1948)
  • The first reported effective treatment was by Derek Denny-Brown with British anti-Lewisite, or Dimercaprol (1951)
  • This was one of the first therapy available in the field of neurology
  •  The first effective oral medication was penicillamine which was discovered in 1956 by John Walshe
  • Trientine and tetrathiomolybdate were also tested
  • Zinc acetate was used by Schouwink and Hoogenraad in 1961 and the 1970's but was later fully developed by Brewer 
    • ]]>     2017-04-21 02:59:30 UTC https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167409639     Symptoms extreme_peridot https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167410974 Symptoms are categorized into categorys. People dont have all of these at the same time.
    1. Liver Disease
    2. Neuropsychiatric Symptoms
    3. Eyes
    4. Kidneys
    5. Heart
    6. Horomones
    Liver Disease
    • tiredness
    • portal hypertension
    • increased bleeding tendency
    • splenomegaly
    • ascites
    • spider anglomata
    • chronic active hepatitis
    • cirrhosis
    • liver cancer
    • acute liver failure
    • hemolytic anemia
    • deranged coagulation
    • hepatic
    Neuropsychiatric
    • mild cognitive deterioration
    • clumsiness
    • changes in behavior
    • parkinsonism
    • hand remor
    • masked facial expressions
    • slurred speech
    • atatia
    • dystonia
    • seizures
    • migranes
    • wing-beating tremor
    • frontal lobe disorder
    • subcortical dementia
    • depression
    • anxiety disorders
    • psychosis
    Eyes
    • Kayser-Fleischer Rings
    • sunflower cataracts
    Kidneys
    • renal tubular acidosis (type 2)
    Heart
    • cardiomyopathy
    Hormones
    • hypoparathyroidism


    ]]>     2017-04-21 03:19:09 UTC https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167410974     Diagnosis extreme_peridot https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167413209
  • If a family member has been diagnosed
  • If symptoms are shown, however it may be diagnosed as something else in this way
    • ]]>     2017-04-21 03:47:26 UTC https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167413209     Treatments extreme_peridot https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167413401
  • Controling copper intake
  • Removing excess copper
  • Treating liver problems
    • ]]>     2017-04-21 03:49:34 UTC https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167413401     extreme_peridot https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167413754 2017-04-21 03:53:50 UTC https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167413754 extreme_peridot https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167413860 2017-04-21 03:55:27 UTC https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167413860 extreme_peridot https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167413967 2017-04-21 03:57:05 UTC https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167413967 Personal Stories extreme_peridot https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167414017 2017-04-21 03:57:42 UTC https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167414017 extreme_peridot https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167414112 2017-04-21 03:58:59 UTC https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167414112 Support Groups extreme_peridot https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167414253 https://www.wilsontherapeutics.com/en/patient-support/

    http://wilsonsdisease.ca/about-wilson-disease]]>     2017-04-21 04:00:42 UTC https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167414253     Resources extreme_peridot https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167414337 http://wilsonsdisease.ca/about-wilson-disease

    https://www.genome.gov/27532725/learning-about-wilson-disease/#al-4

    https://www.niddk.nih.gov/health-information/liver-disease/wilson-disease

    https://en.m.wikipedia.org/wiki/Wilson%27s_disease

    https://www.wilsontherapeutics.com/en/section/wilson-disease/]]>     2017-04-21 04:01:41 UTC https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167414337     extreme_peridot https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167416128 2017-04-21 04:29:56 UTC https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167416128 Kayser-Fleischer Ring extreme_peridot https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167416170 2017-04-21 04:30:57 UTC https://padlet.com/extreme_peridot/9ldjwhcd1t52/wish/167416170