https://padlet.com/dvm22upm/9jnx5wm8tsew en-us 2019-11-06 04:04:33 UTC 2026-02-08 20:08:06 UTC hello@padlet.com dvm22upm https://padlet.com/dvm22upm/9jnx5wm8tsew/wish/407262178 - For vaccine use is H11 aminopeptidase, haemochus galactose glycoprotein and cortortin
- Aminopeptidase ( enzyme use to breakdown blood)  n hamonchus galactose (a part of intestine)  is hidden antigen inside the worm itself (intestine) 
-Hidden antigen use because conserve antigen so no strains, works in all types of sheep, present in all stages
-Adjuvant use is oil and alum
.Oil because longer time to absorp so prolonged immune response 
Cell Mediated Response (CMI)
-Natural infection cause degranulation of mast cell to release histamine and heparin
-Histamine cause vasodilstion and heparin as anticoagulant
-The granules cause contraction of muscle in git causing haemonchus to detach from the wall of git

Vaccine
Cause proliferstion of b cell into plasma cell to produe ig E]]> 2019-11-06 04:05:42 UTC https://padlet.com/dvm22upm/9jnx5wm8tsew/wish/407262178 dvm22upm https://padlet.com/dvm22upm/9jnx5wm8tsew/wish/407263067 -DIVA strategy is to make a free zone of FMD
-Diva strategy can be achieved when infected and vaccinated animal can be differentiate by doing ELISA with the present of 3 non stuctural protein. FMD vaccine is removal of 3NSP of FMDV]]> 2019-11-06 04:09:41 UTC https://padlet.com/dvm22upm/9jnx5wm8tsew/wish/407263067 dvm22upm https://padlet.com/dvm22upm/9jnx5wm8tsew/wish/407263210 -Its better to use kill vaccine instead life or attenuated vaccine cause it less virulent.
-RT-PCR more effective than isolation n identification because its give fast result as its less time for detection and identification
-Oil adjuvant should be used in vaccine as it will prolong the time of APC to absorb the antigen, so that it will prolong the immune response.
-milk and meat safely to consume after withdrawal period.

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