Tay-Sachs Disease by Lindsey Nguyen [Student FVHS] https://padlet.com/ltnguyen169/997qfhct5624 By Lindsey Nguyen, Trisha Vo, and Angelica Gavia en-us 2018-10-26 15:31:47 UTC 2023-06-30 16:35:17 UTC hello@padlet.com What is Tay-Sachs Disease? ltnguyen169 https://padlet.com/ltnguyen169/997qfhct5624/wish/297446922 Tay-Sachs Disease is a rare, inherited disorder that allows the destruction of the nerve cells in the brain and spinal chords. ]]> 2018-10-26 15:34:44 UTC https://padlet.com/ltnguyen169/997qfhct5624/wish/297446922 What is the cause of Tay-Sachs Disease? ltnguyen169 https://padlet.com/ltnguyen169/997qfhct5624/wish/297449359 On chromosome 15 (HEX-A) there is a defective gene that does not allow the production of hexosaminidase. ]]> 2018-10-26 15:39:09 UTC https://padlet.com/ltnguyen169/997qfhct5624/wish/297449359 Treatment for Tay -Sachs Disease ltnguyen169 https://padlet.com/ltnguyen169/997qfhct5624/wish/297452344 There is no cure for Tay-Sachs disease. Life expectancy in children with Tay-Sachs disease is 4 years of age. ]]> 2018-10-26 15:44:22 UTC https://padlet.com/ltnguyen169/997qfhct5624/wish/297452344 What is hexosaminidase? ltnguyen169 https://padlet.com/ltnguyen169/997qfhct5624/wish/297453931 Hexosaminidase is an enzyme that breaks down GM2 gangliosides. High levels of GM2 gangliosides lead to high toxic levels and the destruction of nerve cells in the brain. This then reduces brain function so that one affected with Tay-Sachs Disease cannot survive. ]]> 2018-10-26 15:47:17 UTC https://padlet.com/ltnguyen169/997qfhct5624/wish/297453931 Symptoms include: ltnguyen169 https://padlet.com/ltnguyen169/997qfhct5624/wish/298100983
  • muscle weakness
  • problems with coordination
  • feeling faint 
  • difficulty speaking and swallowing, 
  • hearing and vision loss
  • seizures

    • ]]>     2018-10-29 15:57:28 UTC https://padlet.com/ltnguyen169/997qfhct5624/wish/298100983     ltnguyen169 https://padlet.com/ltnguyen169/997qfhct5624/wish/298102871 2018-10-29 16:00:40 UTC https://padlet.com/ltnguyen169/997qfhct5624/wish/298102871 ltnguyen169 https://padlet.com/ltnguyen169/997qfhct5624/wish/298103872 2018-10-29 16:02:16 UTC https://padlet.com/ltnguyen169/997qfhct5624/wish/298103872 ltnguyen169 https://padlet.com/ltnguyen169/997qfhct5624/wish/298104745 2018-10-29 16:03:38 UTC https://padlet.com/ltnguyen169/997qfhct5624/wish/298104745