Fragile X Syndrome by KYLE JOHNSON https://padlet.com/0800602/8qh624ldnsh3 Genetic Disease Project en-us 2017-02-14 19:44:20 UTC 2017-02-21 19:50:39 UTC hello@padlet.com What is Fragile X Syndrome 0800602 https://padlet.com/0800602/8qh624ldnsh3/wish/153852288 Fragile X syndrome also known as FXS or Martin-Bell syndrome is a genetic condition caused by a lack of proteins in the tips of the chromosomes that causes a developmental problems including learning disabilities and cognitive impairment. ]]> 2017-02-14 19:45:42 UTC https://padlet.com/0800602/8qh624ldnsh3/wish/153852288 Who Discovered Fragile X Syndrome 0800602 https://padlet.com/0800602/8qh624ldnsh3/wish/153855610 In 1943, Martin and Bell showed that fragile X syndrome was X-linked. In 1969, Herbert Lubs developed the chromosomal test for Fragile X. The test was not used extensively until the late 1970's.]]> 2017-02-14 19:56:54 UTC https://padlet.com/0800602/8qh624ldnsh3/wish/153855610 Boy with FXS 0800602 https://padlet.com/0800602/8qh624ldnsh3/wish/153857028 2017-02-14 20:01:28 UTC https://padlet.com/0800602/8qh624ldnsh3/wish/153857028 0800602 https://padlet.com/0800602/8qh624ldnsh3/wish/153858214 2017-02-14 20:06:06 UTC https://padlet.com/0800602/8qh624ldnsh3/wish/153858214 Elevator Talk 0800602 https://padlet.com/0800602/8qh624ldnsh3/wish/153858970 Fragile X Syndrome is a form of mental retardation where the tips of the chromosome are fragile. 
This disease is similar to autism. It is more likely to occur in boys rather than girls. Typically people with this disorder experience delayed learning and intellectual handicaps. ]]> 2017-02-14 20:09:02 UTC https://padlet.com/0800602/8qh624ldnsh3/wish/153858970 Mode of Trasmission 0800602 https://padlet.com/0800602/8qh624ldnsh3/wish/154695568 The FMR1 gene appears in four forms that are defined by the number of repeats of a pattern of DNA called CGG repeats. Individuals with over 200 CGG repeats have a full mutation of the FMR1 gene, which causes fragile X syndrome. Fragile X Syndrome is a X-Linked recessive trait. ]]> 2017-02-17 20:19:52 UTC https://padlet.com/0800602/8qh624ldnsh3/wish/154695568 Chromosome With Fragile X Syndrome 0800602 https://padlet.com/0800602/8qh624ldnsh3/wish/155032528 2017-02-21 00:04:07 UTC https://padlet.com/0800602/8qh624ldnsh3/wish/155032528 Detection 0800602 https://padlet.com/0800602/8qh624ldnsh3/wish/155033087 A simple DNA blood test for fragile X syndrome is widely available and very accurate. This test can detect carriers and fully affected individuals. Any doctor can order the test. Unlike many genetic diseases, it may not be apparent that a person has fragile X.]]> 2017-02-21 00:10:40 UTC https://padlet.com/0800602/8qh624ldnsh3/wish/155033087 Symptoms 0800602 https://padlet.com/0800602/8qh624ldnsh3/wish/155033612 Intellectual disabilities, ranging from mild to severe, attention deficit and hyperactivity, anxiety and unstable mood, autistic behaviors, such as hand-flapping and lack of eye contact, seizures (epilepsy) affect about 25% of people with Fragile X syndrome. FXS can also cause large ears, long face, soft skin and other problems may include ear infections, flat feet, high arched palate, double-jointed fingers and hyper-flexible joints.]]> 2017-02-21 00:16:33 UTC https://padlet.com/0800602/8qh624ldnsh3/wish/155033612 0800602 https://padlet.com/0800602/8qh624ldnsh3/wish/155033843 2017-02-21 00:18:52 UTC https://padlet.com/0800602/8qh624ldnsh3/wish/155033843 Cure 0800602 https://padlet.com/0800602/8qh624ldnsh3/wish/155034465 Currently there is currently no cure for fragile X syndrome. But many therapies can help the affected individuals develop proper social skills and calm any social anxiety. Typically with therapy FXS patients are very friendly and kind. ]]> 2017-02-21 00:25:23 UTC https://padlet.com/0800602/8qh624ldnsh3/wish/155034465 Bibliography 0800602 https://padlet.com/0800602/8qh624ldnsh3/wish/155034901 1. "Fragile X Syndrome - Symptoms and Signs • Fragile X Research - FRAXA Research Foundation." Fragile X Research - FRAXA Research Foundation. N.p., n.d. Web. 17 Feb. 2017.

2. Written by Jacquelyn CafassoMedically Reviewed by. "Everything You Need to Know About Fragile X Syndrome." Healthline. N.p., n.d. Web. 18 Feb. 2017.

3. "Fragile X Syndrome - Genetics Home Reference." U.S. National Library of Medicine. National Institutes of Health, n.d. Web. 20 Feb. 2017.

]]> 2017-02-21 00:31:27 UTC https://padlet.com/0800602/8qh624ldnsh3/wish/155034901 Pedigree of a Family with FXS 0800602 https://padlet.com/0800602/8qh624ldnsh3/wish/155035392 2017-02-21 00:37:12 UTC https://padlet.com/0800602/8qh624ldnsh3/wish/155035392