My remarkable padlet by Jessica Jimenez https://padlet.com/jessicajimenez41/8ocp54sh6rjfcfx2 Made with mirth en-us 2021-03-11 20:43:09 UTC 2021-09-25 04:30:43 UTC hello@padlet.com 1. Autonomic Nervous System Divisions jessicajimenez41 https://padlet.com/jessicajimenez41/8ocp54sh6rjfcfx2/wish/1300191364 (2 Divisions known as):
- Sympathetic
(Adrenergic System)
- Parasympathetic
(Cholinergic System)

(Unit 2 ANS part 1)]]> 2021-03-11 20:43:59 UTC https://padlet.com/jessicajimenez41/8ocp54sh6rjfcfx2/wish/1300191364 2. Neurotransmitters jessicajimenez41 https://padlet.com/jessicajimenez41/8ocp54sh6rjfcfx2/wish/1300256448 Sympathetic:
Acetylcholine (ACH)
Norepinephrine (NE)
Epinephrine (EPI)
Dopamine (DA)

Parasympathetic:
Acetylcholine (ACH)

(Unit 2 ANS part 1 and 2)



]]> 2021-03-11 21:03:18 UTC https://padlet.com/jessicajimenez41/8ocp54sh6rjfcfx2/wish/1300256448 3. Locations where NT are released jessicajimenez41 https://padlet.com/jessicajimenez41/8ocp54sh6rjfcfx2/wish/1300306870
Sympathetic:
-Acetylcholine: released at ganglia from presynaptic nerve endings
-Norepinephrine: released at postganglionic nerve endings
-Epinephrine: acts on adrenergic receptors
-Dopamine: precursor to norepinephrine and stimulates different receptors

Parasympathetic:
-Acetylcholine: released at ganglia and the postganglionic nerve endings

(Unit 2 ANS part 1 and 2)]]> 2021-03-11 21:19:11 UTC https://padlet.com/jessicajimenez41/8ocp54sh6rjfcfx2/wish/1300306870 4. Receptors for each division jessicajimenez41 https://padlet.com/jessicajimenez41/8ocp54sh6rjfcfx2/wish/1300344688 Parasympathetic
Cholinergic Receptors:
-Muscarinic : Located on cell membranes of visceral organs and glands
-Nicotinic 1(Nn):located at ganlgia of the parasympathetic system
-Nicotinic 2(Nm): located on cell membranes of skeletal muscle 
Sympathetic
Adrenergic Receptors: 
-Alpha-1: located on glands, smooth muscles, eyes, most arteries and veins
-Alpha-2: smooth muscle
-Beta-1: located on the heart
-Beta-2 : smooth muscle, lungs, uterus, skeletal muscle, arteries 

(Unit 2 ANS part 1 and 2)

]]> 2021-03-11 21:31:18 UTC https://padlet.com/jessicajimenez41/8ocp54sh6rjfcfx2/wish/1300344688 5. End Organ Response jessicajimenez41 https://padlet.com/jessicajimenez41/8ocp54sh6rjfcfx2/wish/1300402754 Sympathetic:
-Alpha 1: smooth muscles contract and cause vasoconstriction in the vessels and an increased blood pressure
-Alpha 2: decreases contractions of the smooth muscles and causes vasodilation in the vessels and lowers the blood pressure
-Beta 1: increases the force of contractions of the heart and increases the heart rate
-Beta 2: relaxes smooth muscles, relaxes uterine, causes bronchodilation in the bronchi and relaxes the coronary arteries

Parasympathetic:
-Muscarinic: decreases the heart rate, causes bronchoconstriction in the bronchi, increases digestion, increases urination and causes pupillary constriction in the eyes
-Nicotinic 1: conducts impulses across the autonomic ganglia to the postganglionic fibers
-Nicotinic 2: contracts muscle if stimulated

(Unit 2 ANS part 1 and 2)

]]> 2021-03-11 21:51:32 UTC https://padlet.com/jessicajimenez41/8ocp54sh6rjfcfx2/wish/1300402754 6. Drug Classifications jessicajimenez41 https://padlet.com/jessicajimenez41/8ocp54sh6rjfcfx2/wish/1300451421 Sympathetic
- Adrenergic Agonist
stimulates all alpha and beta receptors. Vassoconstriction, increases BP.
- Alpha 1 Adrenergic Agonist
stimulates alpha 1, contraction of smooth muscle, blood vessels constrict, increases blood p.
- Alpha 1 adrenergic blocking drugs
binds to alpha 1 receptors and blocks them. Relaxes smooth muscle. vasodilation and decrease of blood pressure
- Beta 1 Adrenergic agonist
low dose: stimulates dopamine receptors in kidneys causing vasodilation and increased renal flow
Moderate dose: stimulates  beta 1 receptors, increasing force of contraction and cardiac output 
High dose: stimulates alpha-1 receptors causing vasoconstriction, increase blood pressure
-Beta 2 Adrenergic Agonist
stimulates beta 2 receptors causing relaxation of smooth muscle, bronchodilaton and relaxation of the uterus
-Selective Beta 1 Blockers
beta-1 receptor is blocked decreasing cardiac output, HR, and BP
-NonSelective Beta 1 Blockers
block beta-1 and beta-2 receptors decreasing force of contraction,HR, and cardiac output (lowers BP). (can also cause bronchoconstriction)

Parasympathetic:
-Direct –Acting Cholinergic Agonists:
stimulates muscarinic receptors, depending on the drug can cause pupil constriction, a decrease in intraocular pressure, and can prevent urinary retention or constipation
-Indirect –Acting Cholinergic Agonists:
increases ACH at the Nicotinic 2 receptors and used to treat myasthenia gravis
-Anticholinergics/Parasympatholytics
bind to cholinergic receptors to block others drugs (competitive antagonism)

(Unit 2 ANS part 1 and 2)

]]> 2021-03-11 22:10:50 UTC https://padlet.com/jessicajimenez41/8ocp54sh6rjfcfx2/wish/1300451421 7. Drug Examples jessicajimenez41 https://padlet.com/jessicajimenez41/8ocp54sh6rjfcfx2/wish/1300635559 Alpha-1 Adrenergic Agonists
phenylephrine (Neo-Synephrine®) 

Adrenergic Agonists
epinephrine (Adrenalin®)

Alpha-1 Adrenergic Blocker
prazosin (Minipress®)

Beta-1 Adrenergic Agonist  dobutamine 

Beta-2 Adrenergic Agonist      formoterol (Foradil®)

Nonselective Beta Blocker 
   nadolol (Corgard®)

Selective Beta Blocker 
  atenolol (Tenormin®)

Direct Acting Cholinergic Agonist
pilocarpine (Pilocar®)
             
Indirect Acting Cholinergic Agents
neostigmine (Prostigmin®)

Anticholinergic
dicyclomine (Bentyl®)

(Unit 2 Drug list)
]]> 2021-03-11 23:40:38 UTC https://padlet.com/jessicajimenez41/8ocp54sh6rjfcfx2/wish/1300635559