Crouzon Syndrome by Sarish Jamil https://padlet.com/sarish_jamil/8gkb7r1xo2bl Made with fortitude en-us 2019-02-25 12:20:33 UTC 2025-10-23 13:55:21 UTC hello@padlet.com https://padlet-assets.s3.amazonaws.com/icons/Clouds.png Symptoms maryam_ahmed2 https://padlet.com/sarish_jamil/8gkb7r1xo2bl/wish/334801466 * Craniosynostosis
* Frontal Bossing
* Conductive hearing loss
*Poor vision 
*Shallow orbits 
* Parrot-like nose
*Dental crowding
*sleep apnea

]]> 2019-02-25 12:29:42 UTC https://padlet.com/sarish_jamil/8gkb7r1xo2bl/wish/334801466 Causes afeefah_choudhry https://padlet.com/sarish_jamil/8gkb7r1xo2bl/wish/334802700 *Autosomal Dominant genetic disorder 
*Caused by a heterozygous mutation 
*In the FGFR2 gene on chromosome 10q26
*The FGFR2 gene codes for a fibroplast growth factor receptor-2
-Therefore, a mutation in this gene results in overactivated signaling by the FGFR2 which results in premature fusion of bones in the skull (craniosynotsis)
*Most mutations in the FGFR2 gene are point mutations
*Some mutations in the FGFR2 gene can be as a result of insertions and deletions of a small number of nucleotides

]]> 2019-02-25 12:33:37 UTC https://padlet.com/sarish_jamil/8gkb7r1xo2bl/wish/334802700 Treatment sarish_jamil https://padlet.com/sarish_jamil/8gkb7r1xo2bl/wish/334803877 Children with mild Crouzon syndrome may not need treatment. Those with severe Crouzon syndrome should see craniofacial specialist, they may also need surgery. Surgeons may need to perform surgery to open up the sutures and give the brain space to grow. After the surgery, the child needs to wear a special helmet to reshape the skull. 

Surgery can be done to:
*relieve pressure inside the skull
*fix cleft lip or palate
*correct a malformed jaw
*straighten crooked teeth
*correct eye problems

Children may also need speech and language therapy.

]]> 2019-02-25 12:37:49 UTC https://padlet.com/sarish_jamil/8gkb7r1xo2bl/wish/334803877 Diagnosis maryam_ahmed2 https://padlet.com/sarish_jamil/8gkb7r1xo2bl/wish/334806784
It can be diagnosed by carrying out an exam where the baby's face and shape of the skull is looked at. Also there are other ways of examining if a baby has this syndrome which are by using: X-rays, CT and MRI scans that look for fused sutures and increased pressure in the skull. Lastly, mutations in the FGFR2 gene can also be tested.
]]> 2019-02-25 12:46:17 UTC https://padlet.com/sarish_jamil/8gkb7r1xo2bl/wish/334806784 Gene maryam_ahmed2 https://padlet.com/sarish_jamil/8gkb7r1xo2bl/wish/334814780 2019-02-25 13:07:02 UTC https://padlet.com/sarish_jamil/8gkb7r1xo2bl/wish/334814780 Fact sarish_jamil https://padlet.com/sarish_jamil/8gkb7r1xo2bl/wish/334818194 Crouzon syndrome is seen in about 16 per million newborns. It is the most common craniosynostosis syndrome.]]> 2019-02-25 13:14:35 UTC https://padlet.com/sarish_jamil/8gkb7r1xo2bl/wish/334818194 maryam_ahmed2 https://padlet.com/sarish_jamil/8gkb7r1xo2bl/wish/334820677 2019-02-25 13:20:22 UTC https://padlet.com/sarish_jamil/8gkb7r1xo2bl/wish/334820677