https://padlet.com/mepeper/89by1sc4jrw5 Pathophysiology of acute lymphocytic leukemia (ALL) including how leukemia impacts other blood cell types and what type of DNA error is responsible for the Philadelphia chromosome. Your drawing or concept map must also include which stem cell line is affected in acute lymphocytic leukemia en-us 2018-05-04 20:20:12 UTC 2025-10-05 23:16:59 UTC hello@padlet.com mepeper https://padlet.com/mepeper/89by1sc4jrw5/wish/258162418 Stem cell precursors for T or B lymphocytes in bone marrow do not function and do not mature beyond lymphoblast stage. As lymphoblasts become more numerous there is less room for other blood cell types. ]]> 2018-05-04 20:34:02 UTC https://padlet.com/mepeper/89by1sc4jrw5/wish/258162418 mepeper https://padlet.com/mepeper/89by1sc4jrw5/wish/258163319 Because of the increased amount of lymphoblasts there is less room for other blood cell types such as WBCs, RBCs and platelets. ]]> 2018-05-04 20:39:14 UTC https://padlet.com/mepeper/89by1sc4jrw5/wish/258163319 mepeper https://padlet.com/mepeper/89by1sc4jrw5/wish/258166387 ALL branches off of the right to the lymphatic stem cells into the T and B lymphocytes. ]]> 2018-05-04 20:58:56 UTC https://padlet.com/mepeper/89by1sc4jrw5/wish/258166387 mepeper https://padlet.com/mepeper/89by1sc4jrw5/wish/258166832 One cause of ALL is thought to be associated with the Philadelphia chromosome (PhC) which is a translocation of genes between chromosome 9 and 22. 
This affects up to 30% of adults with ALL. ]]> 2018-05-04 21:03:00 UTC https://padlet.com/mepeper/89by1sc4jrw5/wish/258166832