Sickle Cell Anemia by Grace Ho https://padlet.com/lisle202/84u8lnl3zafi By Grace Hoscheidt en-us 2017-05-01 15:50:20 UTC 2025-10-19 03:46:08 UTC hello@padlet.com Prognosis gh20132 https://padlet.com/lisle202/84u8lnl3zafi/wish/169208213 As recently as 1973, the average lifespan for people with sickle cell disease was only 14 years. Today, life expectancy for these patients can reach 50 years and beyond. Women with sickle cell usually live longer than their male counterparts.


]]> 2017-05-01 15:53:52 UTC https://padlet.com/lisle202/84u8lnl3zafi/wish/169208213 gh20132 https://padlet.com/lisle202/84u8lnl3zafi/wish/169210292 2017-05-01 16:01:01 UTC https://padlet.com/lisle202/84u8lnl3zafi/wish/169210292 genetic cause gh20132 https://padlet.com/lisle202/84u8lnl3zafi/wish/169211082 Sickle cell disease is caused by a mutation in the hemoglobin-Beta gene found on chromosome 11. Hemoglobin transports oxygen from the lungs to other parts of the body. Red blood cells with normal hemoglobin (hemoglobin-A) are smooth and round and glide through blood vessels.]]> 2017-05-01 16:04:19 UTC https://padlet.com/lisle202/84u8lnl3zafi/wish/169211082 Symptoms gh20132 https://padlet.com/lisle202/84u8lnl3zafi/wish/169211167 General Symptoms in Infants. In infants, symptoms do not usually appear until late in the baby's first year. Most commonly, they include:
  • Fever
  • Swelling of the hands and feet
  • Pain in the chest, abdomen, limbs, and joints
  • Nosebleeds and frequent upper respiratory infections
General Symptoms in Children. Pain is the most common complaint. It can be acute and severe or chronic, usually from orthopedic problems in the legs and low back. Other symptoms include:
  • Fatigue and shortness of breath (signs of anemia)
  • Irritability
  • Jaundice (yellowish discoloration of the skin and eyes)
Additional Symptoms in Adolescence or Adulthood. Symptoms from childhood continue in adolescence and adulthood. In addition, patients may have:
  • Delayed puberty (in young teenagers)
  • Severe joint pain
  • Progressive anemia
  • Leg sores
  • Gum disease
  • Vision problems
]]> 2017-05-01 16:04:40 UTC https://padlet.com/lisle202/84u8lnl3zafi/wish/169211167 Treatment gh20132 https://padlet.com/lisle202/84u8lnl3zafi/wish/169211238 Bone marrow transplant, also known as stem cell transplant, offers the only potential cure for sickle cell anemia. It's usually reserved for people younger than age 16 because the risks increase for people older than 16. In a red blood cell transfusion, red blood cells are removed from a supply of donated blood, then given intravenously to a person with sickle cell anemia. Blood transfusions increase the number of normal red blood cells in circulation, helping to relieve anemia.]]> 2017-05-01 16:04:57 UTC https://padlet.com/lisle202/84u8lnl3zafi/wish/169211238 gh20132 https://padlet.com/lisle202/84u8lnl3zafi/wish/169214759 2017-05-01 16:16:56 UTC https://padlet.com/lisle202/84u8lnl3zafi/wish/169214759 gh20132 https://padlet.com/lisle202/84u8lnl3zafi/wish/169461585 2017-05-02 15:44:04 UTC https://padlet.com/lisle202/84u8lnl3zafi/wish/169461585 pedagree gh20132 https://padlet.com/lisle202/84u8lnl3zafi/wish/170546134 2017-05-08 15:43:49 UTC https://padlet.com/lisle202/84u8lnl3zafi/wish/170546134 Sex link traits gh20132 https://padlet.com/lisle202/84u8lnl3zafi/wish/170546754 2017-05-08 15:46:06 UTC https://padlet.com/lisle202/84u8lnl3zafi/wish/170546754 Blood alleles gh20132 https://padlet.com/lisle202/84u8lnl3zafi/wish/170547156 2017-05-08 15:47:30 UTC https://padlet.com/lisle202/84u8lnl3zafi/wish/170547156