Remake of Cell Signaling: a modified POGIL by Dafne Cruz https://padlet.com/dcruz1321/7fjp6rvw7965x6sm Read the first card in your column. On your turn, read it aloud, dragging it to column 1-4. Share your thinking with the group. Move on only when there is consensus. Finish with all of one color before moving to the next. Do not assume that columns 1-4 will have all colors, or that each column will have the same amount of cards. en-us 2021-03-15 16:03:52 UTC 2023-02-18 20:26:51 UTC hello@padlet.com dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465271 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465271 dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465277 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465277 The cellular communication method for signaling between cells that are touching, or nearly so. dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465282 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465282 Neurotransmitters are ligands that are released from the axon of one nerve cell diffuse across the synapse, and are picked up by the dendrite of another nerve cell. This helps to propagate the signal across several cells. dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465283 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465283 Morphogens are produced in embryos from a central source early in development. They diffuse throughout the tissue creating a concentration gradient that provides a spatial reference for developing cells. Cells far from the morphogen production will develop into one type of tissue while cells close to the source will develop into a different type of tissue. This allows for differentiation of cell structure early in embryonic development. dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465285 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465285 Quorum sensing is used by bacteria to determine the population density of their species in a local area. Many bacterial functions would be ineffective in small numbers—infecting a host organism with a toxin, for example—and would therefore be a waste of energy and resources to the bacteria. Each bacterium produces a ligand. If the concentration of that ligand reaches a critical concentration, thus indicating a sufficient population density for the response to be effective, all bacteria will respond simultaneously. dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465286 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465286 Paracrine • nearby dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465287 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465287 dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465288 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465288 The cellular communication method that is direct between cells, with no diffusion of the ligand. dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465294 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465294 Pheromones released by a female gamete cell (egg) provide a pathway for the male gamete cell (sperm) to travel, increasing the possibility of fertilization. dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465295 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465295 Following an initial exposure to an allergen, antibodies are produced and imbedded in the PM of mast cells. If the allergen is reintroduced, it interacts with those antibodies, causing the release of histamine. (In turn, histamine can cause inflammation, increased mucous production, or dilation of the blood vessels.) dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465298 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465298 dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465301 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465301 Endocrine • within dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465302 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465302 The cellular communication method that requires a signaling molecule tohave the longest “life”. dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465307 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465307 Some cancer cells release their own growth hormone rather than relying on growth hormones from the host organism or from other cells. This presents challenges to cancer researchers looking for ways to slow the growth of cancer cells. dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465308 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465308 Eph receptors in one membrane bind to ephrin ligands in the membrane of a neighboring cell. New findings reveal that these signaling molecules coordinate developmental processes, as well as the normal physiology and homeostasis of many adult organs. dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465310 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465310 dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465311 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465311 Juxtacrine • beside dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465314 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465314 The cellular communication method for signaling between cells in different parts of an organism. dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465317 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465317 Cells in the pituitary gland produce thyroid stimulating hormone (TSH), which is received by cells in the thyroid. The arrival of TSH in the thyroid triggers production of several hormones, which then travel throughout the body to regulate metabolism. dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465320 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465320 Cells in the human pancreas release insulin when blood sugar levels are elevated. The insulin signals cells in the liver to begin absorbing glucose and convert it to glycogen for storage. dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465323 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465323 Quorum sensing is used by bacteria to determine the population density of their species in a local area. Many bacterial functions would be ineffective in small numbers—infecting a host organism with a toxin, for example—and would therefore be a waste of energy and resources to the bacteria. Each bacterium produces a ligand. If the concentration of that ligand reaches a critical concentration, thus indicating a sufficient population density for the response to be effective, all bacteria will respond simultaneously. dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465325 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465325 dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465328 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465328 Autocrine • self dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465329 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465329 dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465334 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465334 dcruz1321 https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465338 2021-03-15 16:03:52 UTC https://padlet.com/dcruz1321/7fjp6rvw7965x6sm/wish/1311465338