Cystic Fibrosis: Cell Signaling Disease Project by Kayla Hazlotzoswagg https://padlet.com/kaylakcooper/72v2wc9o0ets By: Lexi Peterman and Kayla Cooper 9/29/17 en-us 2017-09-29 11:37:02 UTC 2023-06-07 11:41:30 UTC hello@padlet.com Local Signaling in Animals kaylakcooper https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192401381 Only specific target cells recognize and respond. Includes paracrine signaling (secreting cell that acts on nearby cells by discharging molecules of local regulator into the extracellular fluid.) Synaptic Signaling (nerve cell releases neurotransmitter molecules into a synapse stimulating the target cell.) ]]> 2017-09-29 11:40:15 UTC https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192401381 Long Distance Signaling in Animals kaylakcooper https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192402048 Hormonal signaling (specialized endocrine cells secrete hormones into body fluids into the blood.) Hormones may reach virtually all body cells.]]> 2017-09-29 11:43:30 UTC https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192402048 Signal Transduction Pathway kaylakcooper https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192402364 Transduction is the conversion of a signal from outside the cell to a form that can bring about a specific cellular response.  
Step 1: Chemical signal received by cell (reception)
2: series of events happen (transduction)
3: cellular response (response)]]> 2017-09-29 11:44:58 UTC https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192402364 Extracellular Molecules (Ligands) kaylakcooper https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192403102 Molecules that bind specifically to another molecule, usually a larger one. It basically introduces the change in DNA to the cell because the ligand comes in and binds directly to the DNA altering it causing a disease.]]> 2017-09-29 11:48:20 UTC https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192403102 What a Cell does when it receives a signal (Cystic Fibrosis) kaylakcooper https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192406124 Development of CF develops from misfolded or improperly functioning protein (CTFR) Chloride ion channel doesn't work inhibits flow of water leaving mucus dehydrated and thick and sticky. In normal cells, the cell receives the signal and opens to allow chloride ions to pass the cell membrane which leads to sodium and water passage. This doesn't happen in CF cells because the cells don't act on the signal not letting the water ions through, contributing to dehydration of mucus membranes in the lungs. ]]> 2017-09-29 12:00:55 UTC https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192406124 Cystic Fibrosis kaylakcooper https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192408558 The most common but fatal genetic disease causing the body to produce mucus that clogs lungs which results in infection and blocks pancreas which causes digestive enzymes to not reach the intestines and cause a response to digest food. ]]> 2017-09-29 12:09:25 UTC https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192408558 Role of Protein kinase and Cyclic AMP in CF kaylakcooper https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192408858 Protein Kinase adds phosphate groups to the DNA which changes the protein production to not allow signals to let the water in to hydrate the mucus. Cyclic AMP activates chloride channels in cells.]]> 2017-09-29 12:10:42 UTC https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192408858 kaylakcooper https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192410148 2017-09-29 12:15:56 UTC https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192410148 kaylakcooper https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192410430 2017-09-29 12:16:54 UTC https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192410430 kaylakcooper https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192410672 2017-09-29 12:18:05 UTC https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192410672 kaylakcooper https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192410830 2017-09-29 12:18:50 UTC https://padlet.com/kaylakcooper/72v2wc9o0ets/wish/192410830