Familial Mediterranean Fever by LEELA POKHREL

Gene and/or Chromosome that is mutated

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Located on the short arm of chromosome is the gene that, when mutated, causes FMF.

System/Part of the Body that is affected

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Legs are affected.

Symptoms of Disorder

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Fever, Chest pain, Muscle aches

How is it inherited?

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Familial mediterranean fever is almost always Inherited. If one parent have Familial Mediterranean fever and the

other parent is an unaffected carrier. It may affect child inherited the disorder from inherited parent.

Possible Treatments

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Colchicine this drug is taken in pill. Some people taken one pill a day.

Some side effect show include diarrhea muscle weekness.

What are scientists currently researching about this disorder?

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Colchicine, a medicine that reduces inflammation, may help during an attack and may prevent further attacks.

It can also help prevent a serious medical issue called systemic amyloidosis.

Who discovered it?

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In 1992, the gene responsible for Familial Mediterranean Fever (FMF),

MEFV, was found to reside on the short arm of chromosome 16.

How many people are affected?

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A forty-nine year-old American man of Armenian ancestry was

diagnosed clinically with Familial Mediterranean Fever (FMF) at age 39.

Genetic GO

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Sources

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"Familial Mediterranean Fever." Definition. N.p., n.d. Web. 11 Feb. 2014.

"Familial Mediterranean Fever." - Genetics Home Reference. N.p., 2008. Web. 10 Feb. 2014.

Press, The Associated. "Familial Mediterranean Fever." The New York Times. The New York Times, 31 Dec. 2007. Web. 01 Feb. 2014.

Fisher, Patrick W., L. Tammy Ho, Robert Goldschmidt, Ronald J. Semerdjian, and Gregory W. Rutecki. "Abstract." National Center for Biotechnology Information. U.S. National Library of Medicine, 11 Aug. 2003. Web. 13 Feb. 2014.

"Ariella's Story - Living with Familial Mediterranean Fever." YouTube. YouTube, 26 June 2013. Web. 13 Feb. 2014.

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