Microneedle Patch Delivers Oxygen to Facilitate Healing in Chronic Wounds by Crystal Christopher https://padlet.com/01cchristopher/4hpaatk1p9kypio6 Current Innovation Assignment by Crystal Christopher October 3,2021 NURS5324 University of Texas Tyler- Dr. Post en-us 2021-10-03 21:11:00 UTC 2025-10-09 14:11:08 UTC hello@padlet.com Source of Details- Article published in ACS Applied Bio Materials 01cchristopher https://padlet.com/01cchristopher/4hpaatk1p9kypio6/wish/1787972194 “Flexible Microneedle Array Patch for Chronic Wound Oxygenation and Biofilm Eradication” by Ian Woodhouse, Sina Nejati, Vidhya Selvamani, Hongjie Jiang, Shirisha Chittiboyina, Jesse Grant, Zeynep Mutlu, Jose Waimin, Nader S. Abutaleb, Mohamed N. Seleem, and Rahim Rahimi


]]> 2021-10-03 21:21:07 UTC https://padlet.com/01cchristopher/4hpaatk1p9kypio6/wish/1787972194 Publication Date 01cchristopher https://padlet.com/01cchristopher/4hpaatk1p9kypio6/wish/1787974736 15 June 2021 ]]> 2021-10-03 21:23:20 UTC https://padlet.com/01cchristopher/4hpaatk1p9kypio6/wish/1787974736 Summarization of the Innovation 01cchristopher https://padlet.com/01cchristopher/4hpaatk1p9kypio6/wish/1787979698 Chronic or non-healing wounds is a profound issue individuals encounter worldwide. Annually throughout the United States, statistics show that over 6 million people suffer from delayed wound healing (Woodhouse et al 2021). Patients experience pain and discomfort that can debilitate their normal functioning. These healthcare cases leave a significant burden on family and caregivers as well. Delayed wound healing can often result in an infection that can lead to sepsis or amputation. Scientists at Purdue University created a microneedle patch that can deliver oxygen and bactericidal agents to chronic wounds to facilitate healing. This noninvasive technology is designed to deliver oxygen by releasing calcium peroxide into the wound. This technology has been tested and has been proven to be beneficial in promoting tissue oxygenation. ]]> 2021-10-03 21:28:03 UTC https://padlet.com/01cchristopher/4hpaatk1p9kypio6/wish/1787979698 Video of Microneedle Oxygenation Process 01cchristopher https://padlet.com/01cchristopher/4hpaatk1p9kypio6/wish/1787980268 2021-10-03 21:28:36 UTC https://padlet.com/01cchristopher/4hpaatk1p9kypio6/wish/1787980268 Pros for the Innovation 01cchristopher https://padlet.com/01cchristopher/4hpaatk1p9kypio6/wish/1787981083 * Noninvasive technology- Painless
* Flexible device
* Kills bacteria by delivering oxygen to infected wounds
* Bactericidal properties 
* High levels of cytocompatibility
* Treat antibiotic resistant biofilms

]]> 2021-10-03 21:29:19 UTC https://padlet.com/01cchristopher/4hpaatk1p9kypio6/wish/1787981083 Cons for the Current Innovation 01cchristopher https://padlet.com/01cchristopher/4hpaatk1p9kypio6/wish/1787983969 * Minimal testing- only in porcine tissue samples
* Safety concerns surrounding cell death 

]]> 2021-10-03 21:32:03 UTC https://padlet.com/01cchristopher/4hpaatk1p9kypio6/wish/1787983969 Innovation: Link or Embedded Item 01cchristopher https://padlet.com/01cchristopher/4hpaatk1p9kypio6/wish/1787989616 This illustration shows an infected wound that has a bacterial biofilm layer. It also shows the oxygenation process of the microneedle patch. ]]> 2021-10-03 21:37:28 UTC https://padlet.com/01cchristopher/4hpaatk1p9kypio6/wish/1787989616 Strengths/ Teams 01cchristopher https://padlet.com/01cchristopher/4hpaatk1p9kypio6/wish/1787995519 My most dominate five strengths from Clifton Strength Finders include: relator, learner, achiever, belief, and input. As a leader for the evaluation team, I plan to utilize all five of my strengths to inspire and motivate our team to accomplish our goal in cohesiveness. I chose 5 participants of whom I believe encompass characteristics and abilities that will be beneficial to our team as a whole. 

Team: 
Angelica- Her skills are essential to my team because she possess analytical (strategic thinking) as her most dominate strength. She has the ability to be proactive in challenging circumstances, and analyze information for proper implementation. 

Carter- His most dominate strength is communication. Carter is great for my team because he posses the skill to communicate thoughts, plans, and goals precisely. He would also excel in presenting our groups overall proposal. 

Fernando- His most dominate strength is Focus. Fernando skills are essential because he will help facilitate execution of our goals. His skills are also necessary in order to meet critical deadlines and complete critical task. 

Mathew- Mathew’s most dominate strength is maximize. His skills can facilitate each group members attributes and potential for the team’s well-being. This will allow for optimal results for our team. 

Rachel- Her most dominate strength is restorative. Her skills are essential because she is a problem solver. She has the ability to adapt or resolve challenging issues. 

]]> 2021-10-03 21:42:54 UTC https://padlet.com/01cchristopher/4hpaatk1p9kypio6/wish/1787995519 References 01cchristopher https://padlet.com/01cchristopher/4hpaatk1p9kypio6/wish/1787997260 Woodhouse, I., Nejati, S., Selvamani, V., Jiang, H., Chittiboyina, S., Grant, J., Mutlu, Z., Waimin, J., Abutaleb, N. S., Seleem, M. N., & Rahimi, R. (2021) Flexible Microneedle Array Patch for Chronic Wound Oxygenation and Biofilm Eradication. ACS Publications, 4, 7, 5405–5415. https://doi.org/10.1021/acsabm.1c00087]]> 2021-10-03 21:44:35 UTC https://padlet.com/01cchristopher/4hpaatk1p9kypio6/wish/1787997260 Opinion and Rationale 01cchristopher https://padlet.com/01cchristopher/4hpaatk1p9kypio6/wish/1788088531 As a geriatric nurse, I have observed delayed wound healing on numerous occasions. Whether from preexisting medical conditions such as diabetes or vascular disease these wounds are challenging to heal and treat. I believe that further research and testing needs to be conducted regarding this innovation; however, it does offer beneficial affects. This technology is dire due to the rise of antibiotic resistant infections. The microneedle patch is essential research that can advance medicine by promoting improvements in wound care. 

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