Genomics Case 1 Question 1B by https://padlet.com/haspelr/4glpoa0ayh64fage You are considering genetic testing to aid in selecting chemotherapy. en-us 2021-09-16 14:46:40 UTC 2021-10-28 12:31:17 UTC hello@padlet.com Which panel would you select? haspelr https://padlet.com/haspelr/4glpoa0ayh64fage/wish/1746207940 There are 2 gene panels you are considering for your patient (workshop faculty do not endorse any specific laboratory): 

Laboratory 1: https://bit.ly/TRIGLab1
Laboratory 2: https://bit.ly/TRIGLab2 

Which panel would you select?  Explain your choice in up to three sentences. Review relevant guidelines. 
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]]> 2021-09-16 14:46:40 UTC https://padlet.com/haspelr/4glpoa0ayh64fage/wish/1746207940 https://padlet.com/haspelr/4glpoa0ayh64fage/wish/1767687890 Lab 2; that select panel is all what is needed currently for targeted therapy of that tumor]]> 2021-09-25 19:04:16 UTC https://padlet.com/haspelr/4glpoa0ayh64fage/wish/1767687890 https://padlet.com/haspelr/4glpoa0ayh64fage/wish/1767687906 Panel 1 as tumor may have acquired new mutations ]]> 2021-09-25 19:04:17 UTC https://padlet.com/haspelr/4glpoa0ayh64fage/wish/1767687906 2nd. NCCN guidelines https://padlet.com/haspelr/4glpoa0ayh64fage/wish/1767687927 2021-09-25 19:04:18 UTC https://padlet.com/haspelr/4glpoa0ayh64fage/wish/1767687927 https://padlet.com/haspelr/4glpoa0ayh64fage/wish/1767687953 panel #2 because more clinically relevant and cost efficient]]> 2021-09-25 19:04:20 UTC https://padlet.com/haspelr/4glpoa0ayh64fage/wish/1767687953 Foundation Medicine CDx for the following reasons: https://padlet.com/haspelr/4glpoa0ayh64fage/wish/1767688311 NTRK3 and 2 missing in targeted panel
NCCN recommends TMB which is missing in targeted panel
Improves options for clinical trials for patients to have larger panel]]> 2021-09-25 19:04:45 UTC https://padlet.com/haspelr/4glpoa0ayh64fage/wish/1767688311 https://padlet.com/haspelr/4glpoa0ayh64fage/wish/1767688389 Larger panel for a more comprehensive analysis. Would cast a wider net to identify what is driving patients disease. Limited panel might miss unusual alterations even in select genes. ]]> 2021-09-25 19:04:52 UTC https://padlet.com/haspelr/4glpoa0ayh64fage/wish/1767688389 Panel #1, if still cost effective. Tests the most clinically relevant genes + more for opportunity for more individualized care https://padlet.com/haspelr/4glpoa0ayh64fage/wish/1767689008 2021-09-25 19:05:41 UTC https://padlet.com/haspelr/4glpoa0ayh64fage/wish/1767689008 https://padlet.com/haspelr/4glpoa0ayh64fage/wish/1767690340 2]]> 2021-09-25 19:07:17 UTC https://padlet.com/haspelr/4glpoa0ayh64fage/wish/1767690340