Fungal Disease: Invasive Candidiasis by https://padlet.com/endydani/4ck1d536gkxf126r en-us 2022-12-03 01:34:16 UTC 2025-11-11 03:13:21 UTC hello@padlet.com 1. CDC Page endydani https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407269235 Here I have attached a recent CDC article about the fungal disease called Invasive Candidiasis.]]> 2022-12-03 01:37:34 UTC https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407269235 2. Describe the Disease endydani https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407272545 Invasive Candidiasis is a serious infection that is caused by a kind of yeast or fungus called Candida. Although there are a variety of types of Candida infections/conditions, Invasive Candidiasis in particular can affect an individual's heart, eyes, blood, and their bones as well. Due to this, a bloodstream infection/condition named Candidemia is one of the most common bloodstream infections amongst hospitalized patients. 

Link for image used: 
https://www.mdpi.com/2079-6382/11/7/877]]> 2022-12-03 01:46:07 UTC https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407272545 3. The Causative Agent endydani https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407273166 As aforementioned in the second block, the leading cause of Invasive Candidiasis is a yeast or fungus called Candida. The six main pathogens that cause invasive infections are:
  1. Candida albicans (most common)
  2. Candida glabrata
  3. Candida tropicalis
  4. Candida parapsilosis
  5. Candida krusei
  6. Candida auris

Link for image used: 
https://drfungus.org/knowledge-base/candida-albicans/
]]> 2022-12-03 01:47:46 UTC https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407273166 4. Symptoms of this disease/condition endydani https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407273504 Some of the symptoms of Invasive Candidiasis are:
1. Fever
2. Chills
3. Skin rash
4. Low blood pressure
5. Fatigue
6. Headaches

Link for image used: https://www.merckmanuals.com/professional/infectious-diseases/fungi/candidiasis-invasive]]> 2022-12-03 01:48:40 UTC https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407273504 5. Diagnosis endydani https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407273623 Although there is not a specific way to determine if a patient does in fact have Invasive Candidiasis, one way that healthcare physicians can test for it is by taking a sample of the patient's blood. After they take the blood sample, they will then send it to the laboratory to see if it grows Candida on a petri dish. Another way to determine if a patient has this specific infection/disease is by looking at their medical history, as well as looking to see if the patient's fevers or chills do not improve after taking antibiotic treatments.

Link of image used: https://emcrit.org/ibcc/candida/]]> 2022-12-03 01:49:02 UTC https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407273623 6. Prevention/ Treatment endydani https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407273766 First, it is important to discuss who exactly are at risk of obtaining this specific infection/condition. The groups of people who are at the most risk of getting this disease are: people who are 65 years and older, infants who are younger than one years old, and people who have gotten a blood transfusion or surgery. With that being said, one of the main ways that healthcare physicians can treat Invasive Candidiasis is by administering antifungal medications, which are then given through the patient's vein using an IV. Some of the antifungal medications used are called: Micafungin (the image), Fluconazole, Anidulafungin, and etc. Concerning the duration of treatment for patients with this specific condition, therapy/treatment usually depends on how the patient is responding to the antifungal medications that they are being prescribed. If they respond well to the antibiotics then treatment can last anywhere from two days to two weeks. Whereas for patients that do not respond well or have other underlying issues that are affecting their ability to get better, treatment or therapy can last anywhere from several weeks to 12 months. Lastly, although there really aren't any ways that a person can prevent themselves from obtaining this specific infection, some ways that people can attempt to put themselves at a lower risk of getting Invasive Candidiasis are by washing their hands for 20 seconds, speaking up about if their skin starts to turn red and become painful, and by taking antifungal medication if they recently received an organ transplant or was recently diagnosed with Invasive Candidiasis. 

Link for image used:
https://www.empr.com/home/news/generics-news/micafungin-for-injection-in-50mg-100mg-10ml-single-dose-vials/]]> 2022-12-03 01:49:27 UTC https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407273766 7. Emerging Threats or Successes endydani https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407274001 Peter G. Pappas and his fellow counterparts figured out that Candida can be found on about 50-70% of moderately healthy individuals. They determined that under ideal conditions, the Candida fungus behaves with the host's body/organs in a mutualistic/commensal manner. However, any impairment or damage to that specific host's body/organs can cause overgrowth of the fungus, leading to infections such as Invasive Candidiasis.

Link for image used: https://pubmed.ncbi.nlm.nih.gov/29749387/]]> 2022-12-03 01:50:08 UTC https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407274001 8. Infographic endydani https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407274098
Link for infographic used: 
https://funguseducationhub.org/invasive-candidiasis-infographics-resources/]]> 2022-12-03 01:50:23 UTC https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407274098 9. Featured Scientist and University endydani https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407274472 Peter G. Pappas, MD; Professor of Medicine in the Division of Infectious Diseases at the University of Alabama in Birmingham.

Link for image and credentials used: https://carbonalert.org/wp-content/uploads/2020/08/Pappasbio2020.pdf]]> 2022-12-03 01:51:26 UTC https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407274472 10. Learn more: endydani https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407274581 Video about Invasive Candidiasis and other Candida Infections/Conditions]]> 2022-12-03 01:51:42 UTC https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407274581 11. Fun Fact (Actually A Very Sad Fact) endydani https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407274765 A group of scientists did an experiment on mice to analyze and observe how Candida albicans, which is the most common Candida fungi, affected their brains. Unfortunately, during the experiment the mice suffered from short-term memory loss. Using the data that they collected from the experiment, the scientists concluded that the same protein that surrounded the Candida fungal infection in the mice's brains, is the same exact protein found in patient's with Alzheimer's Disease. ]]> 2022-12-03 01:52:13 UTC https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407274765 12. Sources used (Not including the images) endydani https://padlet.com/endydani/4ck1d536gkxf126r/wish/2407275087
  • https://www.nature.com/articles/nrdp201826
  • https://www.cdc.gov/fungal/diseases/candidiasis/invasive/symptoms.html
  • https://my.clevelandclinic.org/health/diseases/22308-invasive-candidiasis
  • https://pubmed.ncbi.nlm.nih.gov/18778118/#:~:text=Risk%20factors%20are%20diverse%20and,years%2C%20and%20recent%20abdominal%20surgery.
  • https://carbonalert.org/wp-content/uploads/2020/08/Pappasbio2020.pdf
  • https://www.youtube.com/watch?v=7aWm4kYLpwU (Youtube Video)
  • https://oxsci.org/yeast-on-the-brain-could-fungi-be-linked-to-alzheimers-disease/


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