https://padlet.com/vicsmi520/4bdov90a4hi6 A deeper look en-us 2018-01-12 15:03:43 UTC 2024-11-13 11:10:06 UTC hello@padlet.com vicsmi520 https://padlet.com/vicsmi520/4bdov90a4hi6/wish/221716631 Step 1:  The action potential moves down the sarcolemma and down the T-Tubules.  ]]> 2018-01-16 14:34:34 UTC https://padlet.com/vicsmi520/4bdov90a4hi6/wish/221716631 vicsmi520 https://padlet.com/vicsmi520/4bdov90a4hi6/wish/221716741 The brain sends a nerve impulse, known as Action Potential, this causes the voltage gated Calcium ion channels to open and so the Calcium ions flow into the Neuron. This stimulates the release of the Acetylcholine into the cleft. Which then binds to the receptor sight that activates the voltage gated sodium to pump in Na+ and K+ out, making it depolarized. This continues down and opens other voltage gated channels allowing the action potential to move. The concentrations then change the permeability which makes the voltage gated K+ pumps open to allow the K+ to diffuse back across the sarcolemma, which is known as repolarization.]]> 2018-01-16 14:34:48 UTC https://padlet.com/vicsmi520/4bdov90a4hi6/wish/221716741 vicsmi520 https://padlet.com/vicsmi520/4bdov90a4hi6/wish/221716769 Step 2: Transmission of the action potential along the T-tubules causes the adjacent sarcoplasmic reticulum(SR) to release Calcium which flows into the cytosol. ]]> 2018-01-16 14:34:52 UTC https://padlet.com/vicsmi520/4bdov90a4hi6/wish/221716769 vicsmi520 https://padlet.com/vicsmi520/4bdov90a4hi6/wish/221716802 Step 3 and 4: Calcium combines with troponin and removes the blocking action of tropomyosin by changing the shape of the Actin so that the myosin binding site are exposed. Myosin binds to actin to form cross bridges and contraction begins.]]> 2018-01-16 14:34:56 UTC https://padlet.com/vicsmi520/4bdov90a4hi6/wish/221716802 vicsmi520 https://padlet.com/vicsmi520/4bdov90a4hi6/wish/221716897 step 1: Energized myosin head attaches at an actin myofilament, forming a cross bridge. ]]> 2018-01-16 14:35:10 UTC https://padlet.com/vicsmi520/4bdov90a4hi6/wish/221716897 vicsmi520 https://padlet.com/vicsmi520/4bdov90a4hi6/wish/221717722 step 2: ADP and P are released and the myosin head pivots and bends, changing it to bents low-energy state. As a results it pulls the Actin filament towards the M line. ]]> 2018-01-16 14:36:55 UTC https://padlet.com/vicsmi520/4bdov90a4hi6/wish/221717722 vicsmi520 https://padlet.com/vicsmi520/4bdov90a4hi6/wish/221717751 Step 4: As ATP hydrolyzed to ADP and P, The myosin head returns to its prestroke high-energy or "cocked" or position.]]> 2018-01-16 14:36:59 UTC https://padlet.com/vicsmi520/4bdov90a4hi6/wish/221717751 vicsmi520 https://padlet.com/vicsmi520/4bdov90a4hi6/wish/221718065 Step 3: After ATP attaches to myosin, the link between myosin and Actin weakens and the myosin head detaches. ]]> 2018-01-16 14:37:44 UTC https://padlet.com/vicsmi520/4bdov90a4hi6/wish/221718065