Year 2 SBA Queuries/Issues/Problems by

Year 2 SBA Queuries/Issues/Problems by https://padlet.com/rufusmorgan/421rnwumaepxyhvt Made with you guys in mind en-us 2021-01-01 14:50:00 UTC 2023-05-11 07:51:32 UTC hello@padlet.com Post here if... rufusmorgan https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048217532 Please post under here if you have issues with genetics forms, such as queries with questions or answers or if you think these forms have errors on them.]]> 2021-01-01 14:50:49 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048217532 Post here if... rufusmorgan https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048217615 Please post under here if you have issues with all the forms in general, accessing them, using them or anything like this.]]> 2021-01-01 14:51:04 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048217615 Post here if... rufusmorgan https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048218263 Please post under here if you have issues with pharmacology forms, such as queries with questions or answers or if you think these forms have errors on them.]]> 2021-01-01 14:52:59 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048218263 Post here if... rufusmorgan https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048218394 Please post under here if you have issues with cardiovascular and respiratory forms, such as queries with questions or answers or if you think these forms have errors on them.]]> 2021-01-01 14:53:24 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048218394 Post here if... rufusmorgan https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048218530 Please post under here if you have issues with microbiome forms, such as queries with questions or answers or if you think these forms have errors on them.]]> 2021-01-01 14:53:46 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048218530 Post here if... rufusmorgan https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048219029 Please post under here if you have issues with stem cell forms, such as queries with questions or answers or if you think these forms have errors on them.]]> 2021-01-01 14:55:06 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048219029 Unable to access the SBA form https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048227024 I have had an issue accessing the microsoft forms for the SBAs. I could access all the files just fine except the SBAs and it just keeps saying that Microsoft couldn't log me in for some reason. ]]> 2021-01-01 15:17:40 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048227024 GEN2 SBA https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048246775 I thought chromosomes became visible during prophase?]]> 2021-01-01 16:10:22 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048246775 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048317658 Ethanol doesn’t go through phase 2 metabolism. There are just 2 steps to it’s phase 1 metabolism which results in acetic acid ]]> 2021-01-01 18:48:15 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048317658 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048319027 Taken from the emodule: “the brain still has a high water content” ]]> 2021-01-01 18:51:41 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048319027 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048329932 Cyp2a6 activates codeine, not deactivates it and this does occur slowly ]]> 2021-01-01 19:15:18 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048329932 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048331865 I think group A should be written the other way round since the rank is highest lipid solubility to lowest ]]> 2021-01-01 19:20:05 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048331865 PHARM 2 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048374073 I think this question should’ve specified that it was talking about bioavailability (crossing at least one lipid membrane to enter systemic circulation). The way it’s phrased here all answers are applicable since even via the intravenous route, drugs have to cross at least one lipid membrane to reach the target tissue]]> 2021-01-01 21:02:20 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048374073 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048778810 This is contradictory, I think you mean to put the last option as true ]]> 2021-01-02 12:27:37 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048778810 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048781314 We went over this in the f2f session. In some conditions orlistat is reversible. The reaction we are interested in preventing by using orlistst is triglycerides to monoacylglycerols and free fatty acids, and not the conversion to glycerol. Glycerol is hydrophilic so can’t cross the lipid membrane. ]]> 2021-01-02 12:32:44 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048781314 samrah_siddiqi19 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048839067 2021-01-02 14:18:35 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048839067 Can people just remember to clearly signal which emod it is so i can find it quickly, thanks aditya_joshi19 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048859297 2021-01-02 14:46:39 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048859297 PHAR 6 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048987237 Can this be explained please?]]> 2021-01-02 17:36:15 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048987237 Pharm 3 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048998290 I believe this is not necessarily true, if a drug is extremely lipid soluble then a proportion of it can be absorbed in the stomach and not pass through hepatic circulation]]> 2021-01-02 17:50:52 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1048998290 PHAR 8 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1049010265 Can this be explained please?]]> 2021-01-02 18:08:00 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1049010265 MHD 10 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1049945894 Do they not use H2 as an electron donor? So would the correct answer not be true?]]> 2021-01-03 15:19:13 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1049945894 MHD 10 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1049947080 Although, metagenomics is the preferred way to characterise the virome, it's not the only way?]]> 2021-01-03 15:20:22 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1049947080 MHD 3 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1049954502 Is this a mistake?]]> 2021-01-03 15:27:07 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1049954502 MHD 3 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1049955457 Is urine not easy to collect?]]> 2021-01-03 15:27:56 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1049955457 MHD 4 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1049957094 I believe there's a typo here. What do you mean to say?]]> 2021-01-03 15:29:31 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1049957094 MHD 5 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1049974240 is this a mistake?]]> 2021-01-03 15:46:08 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1049974240 MHD 6 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1050010131 Can you explain this please?]]> 2021-01-03 16:20:28 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1050010131 MHD 7 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1050026300 Can you explain this please?]]> 2021-01-03 16:36:12 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1050026300 MHD 8 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1050062489 why is it false?]]> 2021-01-03 17:09:54 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1050062489 samrah_siddiqi19 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1050102277 2021-01-03 17:47:51 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1050102277 samrah_siddiqi19 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1050103269 2021-01-03 17:48:50 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1050103269 CTB 3 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1051646060 There is a steeper conc gradient between the blood and respiring tissues than between the blood and alveoli (oxygen dissociation curve shows this as well) so I don’t understand how this is wrong]]> 2021-01-04 12:32:10 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1051646060 Ctb 1 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1051783154 Hey sorry i was a bit confused not by my choice but by the correct answer, is it because there’s convergence of umbilical vein and another one before the heart? ]]> 2021-01-04 13:30:41 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1051783154 Phar 6 pt1 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1052081129 I thought hypokalemia is caused by blocking of AT1 receptors (so not activation)]]> 2021-01-04 14:44:33 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1052081129 samrah_siddiqi19 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1052607036 2021-01-04 16:40:34 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1052607036 CTB 02 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1053023386 This question is about excitation-contraction coupling. Which statement is INCORRECT?

Required to answer. Single choice.

a) Phase 0 involves depolarisation via the opening of Na+ channels allowing Na+ influx

b) Phases 1-3 is about repolarization and is completed in phase 3

Initial depolarisation opens Ca2+ voltage gated channels

c) Ca2+ influx causes more Ca2+ to enter the cytosol from the Sarcoplasmic reticulum.

The correct answer is c, but aren't all 1-3 repolarisation and these vary in rates?
Also, I thought initial depolarisation (0) triggers L-type calcium channels to open, causing calcium influx and then the calcium-activated calcium release

]]> 2021-01-04 18:17:05 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1053023386 GEN 2 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1055236291 why?]]> 2021-01-05 12:08:34 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1055236291 GEN 7 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1055681688 how does this work?]]> 2021-01-05 14:33:15 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1055681688 GEN 8 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1055818250 Why is this wrong?]]> 2021-01-05 15:01:26 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1055818250 GEN 8 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1055826724 Is this not true?]]> 2021-01-05 15:03:07 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1055826724 GEN 9 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1056455213 I find this question to be a bit confusing?]]> 2021-01-05 17:06:03 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1056455213 GEN 9 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1056462609 Where in the eModule is this stated?]]> 2021-01-05 17:07:30 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1056462609 SCRB5 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1060349872 I think this one should be A since male germ cells go under meitotic arrest and not meiotic]]> 2021-01-06 17:39:04 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1060349872 MHD2 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1062182471 In the emodule, there is a picture of several tubes. In that picture there are only microbes clustered at the oxic end for microaerophile or capnophile. However, in the description below, they mentioned that capnophile grow in elevated level of CO2 and microaerophile grow in low conc of O2. Do we still think these will grow in slightly anaerobic environment?]]> 2021-01-07 07:08:34 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1062182471 MHD2 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1062189434 I cannot find the environment which Streptococci live in. Could anyone tell me where the emodule mentioned it? ]]> 2021-01-07 07:12:05 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1062189434 SCRB2 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1064452785 I think gastrulation starts on day 16 in humans. if you check the picture where the human and mouse development are compared side to side, it says 16.]]> 2021-01-07 18:12:09 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1064452785 MHD9 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1067704214 For question 7, l think in the emodule they mentioned a decrease in Bacteroidetes abundance in asthma patients. And also question 13, the answer maybe wrong due to the same reason.]]> 2021-01-08 16:32:12 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1067704214 CTB7 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1070530162 Hi, do we need to know the whole process of coagulation, as it is not detailedly illustrating in the emodule?]]> 2021-01-10 02:56:59 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1070530162 GEN3 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1080934253 Don’t LTR retro transposons also code for a reverse transcriptase? Using the pol gene?

Apologies if I’m wrong or have misunderstood the question!]]> 2021-01-12 22:12:18 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1080934253 PHAR3 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1082668155 The metabolism of THC is from delta9-THC -> 11OH-THC -> THC-COOH.

If it gets less lipid soluble/more water soluble at each stage, aren't both the first two options incorrect?]]> 2021-01-13 12:20:40 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1082668155 Phar 2 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1085269245 If intravenous drugs have 100% bioavailability, and they also undergo metabolism, excretion and distribution, then shouldnt the only determining factor be absorption? Since thats the only factor that is improved/bypassed by intravenous, meaning the others don't affect it?]]> 2021-01-13 22:55:01 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1085269245 GEN 9 jasperwzc https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1085441310 What makes this second statement incorrect?]]> 2021-01-14 00:51:53 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1085441310 samrah_siddiqi19 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1090807394 2021-01-15 11:46:54 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1090807394 Gen3 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1093340452 Is the ddNTP as the same as the dNTP reversibly modified with 3'blocks mentioned in the emodule?]]> 2021-01-16 02:52:00 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1093340452 Post here if... rufusmorgan https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1432346346 Please post under here if you have issues with immunology forms, such as queries with questions or answers or if you think these forms have errors on them.]]> 2021-04-19 10:10:00 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1432346346 Post here if... rufusmorgan https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1432347160 Please post under here if you have issues with cancer biology forms, such as queries with questions or answers or if you think these forms have errors on them.]]> 2021-04-19 10:10:21 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1432347160 Post here if... rufusmorgan https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1432349070 Please post under here if you have issues with neuroscience forms, such as queries with questions or answers or if you think these forms have errors on them.]]> 2021-04-19 10:11:12 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1432349070 NEU5 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1437746387 In the case of H.M, he had his hippocampus removed but was still able to access his long-term memory? Based on that, doesn’t that indicate that the hippocampus isn’t required?]]> 2021-04-20 13:18:35 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1437746387 NEU8 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1438068338 Does the link for this form work? ]]> 2021-04-20 14:18:13 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1438068338 CBIO 2 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1441999008 p53 is....

A gatekeeper protein

A caretaker protein

An oncogene

The answer was that p53 is a caretaker protein however, p53 was found to be a double-agent as some mutations resemble those of oncogenes while its normal expression pattern does resemble that of a tumour suppressor gene. It would be more appropriate if the answer to this question was "double-agent".

]]> 2021-04-21 11:03:17 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1441999008 CBIO5 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1444132261 I think this Q should be true since other polyamoviruses have been associated with cancer, though only MCPyV has causal evidence.]]> 2021-04-21 18:53:01 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1444132261 samrah_siddiqi19 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1452001254 2021-04-23 14:38:27 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1452001254 IMI7 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1454576967 If restriction factors have a wide range of genes that can be used, wouldn’t that suggest that they can target a broad range of pathogens?]]> 2021-04-24 12:47:17 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1454576967 NEU 2 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1456202494 Why is the first one incorrect?]]> 2021-04-25 12:32:36 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1456202494 NEU 8 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1456817668 Why is the reason false?]]> 2021-04-25 19:01:36 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1456817668 Neu 1 https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1464480965 Isn't the CNS involved through the use of interneurons of the spinal cord? I thought reflexes just don't involve the brain specifically? Also, what exactly is a voluntary reflex?]]> 2021-04-27 14:14:08 UTC https://padlet.com/rufusmorgan/421rnwumaepxyhvt/wish/1464480965